Details for: Slc6a4

Gene ID: 25553

Symbol: Slc6a4

Ensembl ID: ENSRNOG00000003476

Description: solute carrier family 6 member 4

Associated with

Other Information

Genular Protein ID: 3602969164

Symbol: SC6A4_RAT

Name: Sodium-dependent serotonin transporter

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1765155

Title: Isolation of cDNAs encoding a novel member of the neurotransmitter transporter gene family.

PubMed ID: 1765155

DOI: 10.1016/0014-5793(91)81418-8

PubMed ID: 1944572

Title: Cloning and expression of a functional serotonin transporter from rat brain.

PubMed ID: 1944572

DOI: 10.1038/354066a0

PubMed ID: 1948036

Title: Cloning of a serotonin transporter affected by antidepressants.

PubMed ID: 1948036

DOI: 10.1126/science.1948036

PubMed ID: 8968583

Title: Single-channel currents produced by the serotonin transporter and analysis of a mutation affecting ion permeation.

PubMed ID: 8968583

DOI: 10.1016/s0006-3495(96)79506-1

PubMed ID: 8601815

Title: Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract.

PubMed ID: 8601815

DOI: 10.1523/jneurosci.16-07-02352.1996

PubMed ID: 10407194

Title: Molecular cloning, expression and characterization of a bovine serotonin transporter.

PubMed ID: 10407194

DOI: 10.1016/s0169-328x(99)00178-3

PubMed ID: 10716733

Title: Oligomerization of serotonin transporter and its functional consequences.

PubMed ID: 10716733

DOI: 10.1073/pnas.97.7.3106

PubMed ID: 11709063

Title: Regulation of the serotonin transporter by interacting proteins.

PubMed ID: 11709063

DOI: 10.1042/0300-5127:0290722

PubMed ID: 12944413

Title: Glycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter. A specific role for sialic acid residues.

PubMed ID: 12944413

DOI: 10.1074/jbc.m306360200

PubMed ID: 14642278

Title: Regulating the conducting states of a mammalian serotonin transporter.

PubMed ID: 14642278

DOI: 10.1016/s0896-6273(03)00605-6

PubMed ID: 18317590

Title: Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans.

PubMed ID: 18317590

DOI: 10.1172/jci33374

PubMed ID: 21730057

Title: A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport.

PubMed ID: 21730057

DOI: 10.1074/jbc.m111.250308

PubMed ID: 31201245

Title: Withdrawal: Glycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter: a specific role for sialic acid residues.

PubMed ID: 31201245

DOI: 10.1074/jbc.w119.009466

PubMed ID: 15627510

Title: Role of C-terminal region in the functional regulation of rat serotonin transporter (SERT).

PubMed ID: 15627510

DOI: 10.1016/j.neuint.2004.08.008

PubMed ID: 16870614

Title: Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2.

PubMed ID: 16870614

DOI: 10.1074/jbc.m602848200

PubMed ID: 17310063

Title: Phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMP.

PubMed ID: 17310063

DOI: 10.1074/jbc.m611353200

Sequence Information:

  • Length: 630
  • Mass: 70172
  • Checksum: 44DA7C5888C403EE
  • Sequence:
  • METTPLNSQK VLSECKDRED CQENGVLQKG VPTTADRAEP SQISNGYSAV PSTSAGDEAS 
    HSIPAATTTL VAEIRQGERE TWGKKMDFLL SVIGYAVDLG NIWRFPYICY QNGGGAFLLP 
    YTIMAIFGGI PLFYMELALG QYHRNGCISI WRKICPIFKG IGYAICIIAF YIASYYNTII 
    AWALYYLISS LTDRLPWTSC TNSWNTGNCT NYFAQDNITW TLHSTSPAEE FYLRHVLQIH 
    QSKGLQDLGT ISWQLTLCIV LIFTVIYFSI WKGVKTSGKV VWVTATFPYI VLSVLLVRGA 
    TLPGAWRGVV FYLKPNWQKL LETGVWVDAA AQIFFSLGPG FGVLLAFASY NKFNNNCYQD 
    ALVTSVVNCM TSFVSGFVIF TVLGYMAEMR NEDVSEVAKD AGPSLLFITY AEAIANMPAS 
    TFFAIIFFLM LITLGLDSTF AGLEGVITAV LDEFPHIWAK RREWFVLIVV ITCVLGSLLT 
    LTSGGAYVVT LLEEYATGPA VLTVALIEAV AVSWFYGITQ FCSDVKEMLG FSPGWFWRIC 
    WVAISPLFLL FIICSFLMSP PQLRLFQYNY PHWSIVLGYC IGMSSVICIP TYIIYRLIST 
    PGTLKERIIK SITPETPTEI PCGDIRMNAV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.