Abcc8 | ENSRNOG00000021130 | NCBI 25559

Details for: Abcc8

Gene ID: 25559

Symbol: Abcc8

Ensembl ID: ENSRNOG00000021130

Description: ATP binding cassette subfamily C member 8

Associated with

Atp sensitive potassium channels
(R-RNO-1296025)
Integration of energy metabolism
(R-RNO-163685)
Inwardly rectifying k+ channels
(R-RNO-1296065)
Metabolism
(R-RNO-1430728)
Neuronal system
(R-RNO-112316)
Potassium channels
(R-RNO-1296071)
Regulation of insulin secretion
(R-RNO-422356)
Abc-type transporter activity
(GO:0140359)
Adp binding
(GO:0043531)
Atpase-coupled monoatomic cation transmembrane transporter activity
(GO:0019829)
Atpase-coupled transmembrane transporter activity
(GO:0042626)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cellular response to organic substance
(GO:0071310)
Female pregnancy
(GO:0007565)
Glutamate secretion, neurotransmission
(GO:0061535)
Intracellular glucose homeostasis
(GO:0001678)
Inward rectifying potassium channel
(GO:0008282)
Membrane
(GO:0016020)
Memory
(GO:0007613)
Negative regulation of angiogenesis
(GO:0016525)
Negative regulation of blood-brain barrier permeability
(GO:1905604)
Negative regulation of glial cell proliferation
(GO:0060253)
Negative regulation of insulin secretion
(GO:0046676)
Negative regulation of low-density lipoprotein particle clearance
(GO:0010989)
Negative regulation of neuroblast migration
(GO:0061855)
Negative regulation of neurogenesis
(GO:0050768)
Neuromuscular process
(GO:0050905)
Plasma membrane
(GO:0005886)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus
(GO:0035774)
Positive regulation of potassium ion transport
(GO:0043268)
Positive regulation of tight junction disassembly
(GO:1905075)
Positive regulation of tumor necrosis factor production
(GO:0032760)
Positive regulation of uterine smooth muscle relaxation
(GO:1900721)
Potassium channel activity
(GO:0005267)
Potassium ion-transporting atpase complex
(GO:0031004)
Potassium ion import across plasma membrane
(GO:1990573)
Potassium ion transport
(GO:0006813)
Protein-containing complex
(GO:0032991)
Response to insulin
(GO:0032868)
Response to lipopolysaccharide
(GO:0032496)
Response to ph
(GO:0009268)
Response to xenobiotic stimulus
(GO:0009410)
Response to zinc ion
(GO:0010043)
Sarcolemma
(GO:0042383)
Sulfonylurea receptor activity
(GO:0008281)
Synaptic vesicle membrane
(GO:0030672)
Transmembrane transport
(GO:0055085)
Transmembrane transporter binding
(GO:0044325)
Visual learning
(GO:0008542)

Other Information

Proteins

ATP-binding cassette sub-family C member 8

Genular Protein ID: 3950294481

Symbol: ABCC8_RAT

Name: ATP-binding cassette sub-family C member 8

UniProtKB Accession Codes:

Q09429 O54989 P70532 Q9EQT0

Database IDs:

Citations:

PubMed ID: 7716547

Title: Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion.

PubMed ID: 7716547

DOI: 10.1126/science.7716547

PubMed ID: 8942641

Title: The high-affinity sulfonylurea receptor: distribution, glycosylation, purification, and immunoprecipitation of two forms from endocrine and neuroendocrine cell lines.

PubMed ID: 8942641

DOI: 10.1021/bi960777y

Sequence Information:

Length: 1582
Mass: 177185
Checksum: 7C57A1CFC86B9214
Sequence:

MPLAFCGTEN HSAAYRVDQG VLNNGCFVDA LNVVPHVFLL FITFPILFIG WGSQSSKVHI 
HHSTWLHFPG HNLRWILTFI LLFVLVCEIA EGILSDGVTE SRHLHLYMPA GMAFMAAITS 
VVYYHNIETS NFPKLLIALL IYWTLAFITK TIKFVKFYDH AIGFSQLRFC LTGLLVILYG 
MLLLVEVNVI RVRRYVFFKT PREVKPPEDL QDLGVRFLQP FVNLLSKGTY WWMNAFIKTA 
HKKPIDLRAI GKLPIAMRAL TNYQRLCLAF DAQARKDTQS QQGARAIWRA LCHAFGRRLV 
LSSTFRILAD LLGFAGPLCI FGIVDHLGKE NHVFQPKTQF LGVYFVSSQE FLGNAYVLAV 
LLFLALLLQR TFLQASYYVA IETGINLRGA IQTKIYNKIM HLSTSNLSMG EMTAGQICNL 
VAIDTNQLMW FFFLCPNLWA MPVQIIVGVI LLYYILGVSA LIGAAVIILL APVQYFVATK 
LSQAQRSTLE YSNERLKQTN EMLRGIKLLK LYAWENIFCS RVEKTRRKEM TSLRAFAVYT 
SISIFMNTAI PIAAVLITFV GHVSFFKESD FSPSVAFASL SLFHILVTPL FLLSSVVRST 
VKALVSVQKL SEFLSSAEIR EEQCAPREPA PQGQAGKYQA VPLKVVNRKR PAREEVRDLL 
GPLQRLTPST DGDADNFCVQ IIGGFFTWTP DGIPTLSNIT IRIPRGQLTM IVGQVGCGKS 
SLLLATLGEM QKVSGAVFWN SSLPDSEGED PSNPERETAA DSDARSRGPV AYASQKPWLL 
NATVEENITF ESPFNKQRYK MVIEACSLQP DIDILPHGDQ TQIGERGINL SGGQRQRISV 
ARALYQHTNV VFLDDPFSAL DVHLSDHLMQ AGILELLRDD KRTVVLVTHK LQYLPHADWI 
IAMKDGTIQR EGTLKDFQRS ECQLFEHWKT LMNRQDQELE KETVMERKAP EPSQGLPRAM 
SSRDGLLLDE DEEEEEAAES EEDDNLSSVL HQRAKIPWRA CTKYLSSAGI LLLSLLVFSQ 
LLKHMVLVAI DYWLAKWTDS ALVLSPAARN CSLSQECALD QSVYAMVFTV LCSLGIALCL 
VTSVTVEWTG LKVAKRLHRS LLNRIILAPM RFFETTPLGS ILNRFSSDCN TIDQHIPSTL 
ECLSRSTLLC VSALAVISYV TPVFLVALLP LAVVCYFIQK YFRVASRDLQ QLDDTTQLPL 
LSHFAETVEG LTTIRAFRYE ARFQQKLLEY TDSNNIASLF LTAANRWLEV RMEYIGACVV 
LIAAATSISN SLHRELSAGL VGLGLTYALM VSNYLNWMVR NLADMEIQLG AVKRIHTLLK 
TEAESYEGLL APSLIPKNWP DQGKIQIQNL SVRYDSSLKP VLKHVNALIS PGQKIGICGR 
TGSGKSSFSL AFFRMVDMFE GRIIIDGIDI AKLPLHTLRS RLSIILQDPV LFSGTIRFNL 
DPEKKCSDST LWEALEIAQL KLVVKALPGG LDAIITEGGE NFSQGQRQLF CLARAFVRKT 
SIFIMDEATA SIDMATENIL QKVVMTAFAD RTVVTIAHRV HTILSADLVM VLKRGAILEF 
DKPEKLLSQK DSVFASFVRA DK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.