Ywhaz | ENSRNOG00000008195 | NCBI 25578

Details for: Ywhaz

Gene ID: 25578

Symbol: Ywhaz

Ensembl ID: ENSRNOG00000008195

Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

Associated with

Activation of bad and translocation to mitochondria
(R-RNO-111447)
Activation of bh3-only proteins
(R-RNO-114452)
Adaptive immune system
(R-RNO-1280218)
Apoptosis
(R-RNO-109581)
Cell cycle
(R-RNO-1640170)
Cell cycle checkpoints
(R-RNO-69620)
Chk1/chk2(cds1) mediated inactivation of cyclin b:cdk1 complex
(R-RNO-75035)
Cytokine signaling in immune system
(R-RNO-1280215)
Deactivation of the beta-catenin transactivating complex
(R-RNO-3769402)
Foxo-mediated transcription
(R-RNO-9614085)
G2/m checkpoints
(R-RNO-69481)
G2/m dna damage checkpoint
(R-RNO-69473)
Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Gp1b-ix-v activation signalling
(R-RNO-430116)
Hemostasis
(R-RNO-109582)
Immune system
(R-RNO-168256)
Interleukin-3, interleukin-5 and gm-csf signaling
(R-RNO-512988)
Intrinsic pathway for apoptosis
(R-RNO-109606)
Ksrp (khsrp) binds and destabilizes mrna
(R-RNO-450604)
Metabolism of rna
(R-RNO-8953854)
Notch4 activation and transmission of signal to the nucleus
(R-RNO-9013700)
Platelet activation, signaling and aggregation
(R-RNO-76002)
Programmed cell death
(R-RNO-5357801)
Rap1 signalling
(R-RNO-392517)
Regulation of localization of foxo transcription factors
(R-RNO-9614399)
Regulation of mrna stability by proteins that bind au-rich elements
(R-RNO-450531)
Rho gtpase effectors
(R-RNO-195258)
Rho gtpases activate pkns
(R-RNO-5625740)
Rna polymerase ii transcription
(R-RNO-73857)
Signaling by interleukins
(R-RNO-449147)
Signaling by notch
(R-RNO-157118)
Signaling by notch4
(R-RNO-9013694)
Signaling by rho gtpases
(R-RNO-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-RNO-9716542)
Signaling by wnt
(R-RNO-195721)
Tcf dependent signaling in response to wnt
(R-RNO-201681)
Tp53 regulates metabolic genes
(R-RNO-5628897)
Transcriptional regulation by tp53
(R-RNO-3700989)
Angiogenesis
(GO:0001525)
Cell leading edge
(GO:0031252)
Cellular response to glucose starvation
(GO:0042149)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna-binding transcription factor binding
(GO:0140297)
Erk1 and erk2 cascade
(GO:0070371)
Establishment of golgi localization
(GO:0051683)
Glutamatergic synapse
(GO:0098978)
Golgi reassembly
(GO:0090168)
Hippocampal mossy fiber to ca3 synapse
(GO:0098686)
Histamine secretion by mast cell
(GO:0002553)
Identical protein binding
(GO:0042802)
Lung development
(GO:0030324)
Melanosome
(GO:0042470)
Negative regulation of innate immune response
(GO:0045824)
Negative regulation of protein localization to nucleus
(GO:1900181)
Negative regulation of torc1 signaling
(GO:1904262)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphoserine residue binding
(GO:0050815)
Postsynaptic specialization
(GO:0099572)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein kinase binding
(GO:0019901)
Protein sequestering activity
(GO:0140311)
Protein targeting
(GO:0006605)
Protein targeting to mitochondrion
(GO:0006626)
Regulation of erk1 and erk2 cascade
(GO:0070372)
Regulation of programmed cell death
(GO:0043067)
Regulation of synapse maturation
(GO:0090128)
Respiratory system process
(GO:0003016)
Response to xenobiotic stimulus
(GO:0009410)
Signal transduction
(GO:0007165)
Synaptic target recognition
(GO:0008039)
Transmembrane transporter binding
(GO:0044325)
Tube formation
(GO:0035148)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

14-3-3 protein zeta/delta

Genular Protein ID: 2501939072

Symbol: 1433Z_RAT

Name: 14-3-3 protein zeta/delta

UniProtKB Accession Codes:

P63102 P35215 P70197 P97286 Q52KK1 Q6IRF4

Database IDs:

Citations:

PubMed ID: 7984035

Title: Molecular cloning of rat cDNAs for the zeta and theta subtypes of 14-3-3 protein and differential distributions of their mRNAs in the brain.

PubMed ID: 7984035

DOI: 10.1016/0169-328x(94)90285-2

PubMed ID: 8972907

Title: A gene variation of 14-3-3 zeta isoform in rat hippocampus.

PubMed ID: 8972907

DOI: 10.1016/s0378-1119(96)00368-x

PubMed ID: 7822263

Title: cDNA cloning and characterization of mitochondrial import stimulation factor (MSF) purified from rat liver cytosol.

PubMed ID: 7822263

DOI: 10.1093/oxfordjournals.jbchem.a124541

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11427721

Title: Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis.

PubMed ID: 11427721

DOI: 10.1073/pnas.141118798

PubMed ID: 8024705

Title: Cloning and characterization of the epsilon and zeta isoforms of the 14-3-3 proteins.

PubMed ID: 8024705

DOI: 10.1089/dna.1994.13.629

PubMed ID: 12615066

Title: Characterization of zetin 1/rBSPRY, a novel binding partner of 14-3-3 proteins.

PubMed ID: 12615066

DOI: 10.1016/s0006-291x(03)00182-7

PubMed ID: 16959763

Title: Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

PubMed ID: 16959763

DOI: 10.1074/mcp.m600147-mcp200

PubMed ID: 21478148

Title: Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection.

PubMed ID: 21478148

DOI: 10.1074/jbc.m110.197707

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 245
Mass: 27771
Checksum: 2164DF3793B45B7A
Sequence:

MDKNELVQKA KLAEQAERYD DMAACMKSVT EQGAELSNEE RNLLSVAYKN VVGARRSSWR 
VVSSIEQKTE GAEKKQQMAR EYREKIETEL RDICNDVLSL LEKFLIPNAS QPESKVFYLK 
MKGDYYRYLA EVAAGDDKKG IVDQSQQAYQ EAFEISKKEM QPTHPIRLGL ALNFSVFYYE 
ILNSPEKACS LAKTAFDEAI AELDTLSEES YKDSTLIMQL LRDNLTLWTS DTQGDEAEAG 
EGGEN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ywhaz

Associated with

Other Information

Molecular cloning of rat cDNAs for the zeta and theta subtypes of 14-3-3 protein and differential distributions of their mRNAs in the brain. PubMed ID: 7984035

A gene variation of 14-3-3 zeta isoform in rat hippocampus. PubMed ID: 8972907

cDNA cloning and characterization of mitochondrial import stimulation factor (MSF) purified from rat liver cytosol. PubMed ID: 7822263

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis. PubMed ID: 11427721

Cloning and characterization of the epsilon and zeta isoforms of the 14-3-3 proteins. PubMed ID: 8024705

Characterization of zetin 1/rBSPRY, a novel binding partner of 14-3-3 proteins. PubMed ID: 12615066

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling. PubMed ID: 16959763

Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection. PubMed ID: 21478148

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903