Alpl | ENSRNOG00000013954 | NCBI 25586

Details for: Alpl

Gene ID: 25586

Symbol: Alpl

Ensembl ID: ENSRNOG00000013954

Description: alkaline phosphatase, biomineralization associated

Associated with

Metabolism of proteins
(R-RNO-392499)
Post-translational modification: synthesis of gpi-anchored proteins
(R-RNO-163125)
Post-translational protein modification
(R-RNO-597592)
Adp phosphatase activity
(GO:0043262)
Alkaline phosphatase activity
(GO:0004035)
Atp hydrolysis activity
(GO:0016887)
Bone mineralization
(GO:0030282)
Calcium ion binding
(GO:0005509)
Calcium ion homeostasis
(GO:0055074)
Cellular homeostasis
(GO:0019725)
Cellular response to organic cyclic compound
(GO:0071407)
Cementum mineralization
(GO:0071529)
Dephosphorylation
(GO:0016311)
Developmental process involved in reproduction
(GO:0003006)
Endochondral ossification
(GO:0001958)
Extracellular matrix
(GO:0031012)
Extracellular membrane-bounded organelle
(GO:0065010)
Extracellular space
(GO:0005615)
Futile creatine cycle
(GO:0140651)
Inhibition of non-skeletal tissue mineralization
(GO:0140928)
Inorganic diphosphate phosphatase activity
(GO:0004427)
Mitochondrial intermembrane space
(GO:0005758)
Mitochondrial membrane
(GO:0031966)
Phosphate ion homeostasis
(GO:0055062)
Phosphoamidase activity
(GO:0050187)
Phosphoethanolamine phosphatase activity
(GO:0052732)
Plasma membrane
(GO:0005886)
Positive regulation of cold-induced thermogenesis
(GO:0120162)
Pyridoxal phosphatase activity
(GO:0033883)
Pyridoxal phosphate metabolic process
(GO:0042822)
Pyrophosphatase activity
(GO:0016462)
Response to antibiotic
(GO:0046677)
Response to glucocorticoid
(GO:0051384)
Response to insulin
(GO:0032868)
Response to lipopolysaccharide
(GO:0032496)
Response to macrophage colony-stimulating factor
(GO:0036005)
Response to organic cyclic compound
(GO:0014070)
Response to sodium phosphate
(GO:1904383)
Response to vitamin b6
(GO:0034516)
Response to vitamin d
(GO:0033280)
Side of membrane
(GO:0098552)

Other Information

Proteins

Alkaline phosphatase liver/bone/kidney isozyme

Genular Protein ID: 1374509903

Symbol: PPBT_RAT

Name: Alkaline phosphatase liver/bone/kidney isozyme

UniProtKB Accession Codes:

P08289 P14055 P70707

Database IDs:

Citations:

PubMed ID: 3422431

Title: Structure and expression of rat osteosarcoma (ROS 17/2.8) alkaline phosphatase: product of a single copy gene.

PubMed ID: 3422431

DOI: 10.1073/pnas.85.2.319

PubMed ID: 2895632

Title: Primary structure of rat liver alkaline phosphatase deduced from its cDNA.

PubMed ID: 2895632

DOI: 10.1042/bj2490661

PubMed ID: 2544423

Title: Isolation and characterization of a rat liver alkaline phosphatase gene. A single gene with two promoters.

PubMed ID: 2544423

DOI: 10.1111/j.1432-1033.1989.tb14822.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2834351

Title: Chemical identification of lipid components in the membranous form of rat liver alkaline phosphatase.

PubMed ID: 2834351

DOI: 10.1093/oxfordjournals.jbchem.a122211

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 32710882

Title: Lipid composition modulates ATP hydrolysis and calcium phosphate mineral propagation by TNAP-harboring proteoliposomes.

PubMed ID: 32710882

DOI: 10.1016/j.abb.2020.108482

Sequence Information:

Length: 524
Mass: 57659
Checksum: BD75A4B87117DF03
Sequence:

MILPFLVLAI GTCLTNSFVP EKEKDPSYWR QQAQETLKNA LKLQKLNTNV AKNIIMFLGD 
GMGVSTVTAA RILKGQLHHN TGEETRLEMD KFPFVALSKT YNTNAQVPDS AGTATAYLCG 
VKANEGTVGV SAATERTRCN TTQGNEVTSI LRWAKDAGKS VGIVTTTRVN HATPSAAYAH 
SADRDWYSDN EMPPEALSQG CKDIAYQLMH NIKDIDVIMG GGRKYMYPKN RTDVEYELDE 
KARGTRLDGL DLISIWKSFK PRHKHSHYVW NRTELLALDP SRVDYLLGLF EPGDMQYELN 
RNNLTDPSLS EMVEVALRIL TKNPKGFFLL VEGGRIDHGH HEGKAKQALH EAVEMDEAIG 
KAGTMTSQKD TLTVVTADHS HVFTFGGYTP RGNSIFGLAP MVSDTDKKPF TAILYGNGPG 
YKVVDGEREN VSMVDYAHNN YQAQSAVPLR HETHGGEDVA VFAKGPMAHL LHGVHEQNYI 
PHVMAYASCI GANLDHCAWA SSASSPSPGA LLLPLALFPL RTLF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Alpl

Associated with

Other Information

Structure and expression of rat osteosarcoma (ROS 17/2.8) alkaline phosphatase: product of a single copy gene. PubMed ID: 3422431

Primary structure of rat liver alkaline phosphatase deduced from its cDNA. PubMed ID: 2895632

Isolation and characterization of a rat liver alkaline phosphatase gene. A single gene with two promoters. PubMed ID: 2544423

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Chemical identification of lipid components in the membranous form of rat liver alkaline phosphatase. PubMed ID: 2834351

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Lipid composition modulates ATP hydrolysis and calcium phosphate mineral propagation by TNAP-harboring proteoliposomes. PubMed ID: 32710882