Hcrtr1 | ENSRNOG00000013838 | NCBI 25593

Details for: Hcrtr1

Gene ID: 25593

Symbol: Hcrtr1

Ensembl ID: ENSRNOG00000013838

Description: hypocretin receptor 1

Associated with

Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (q) signalling events
(R-RNO-416476)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Orexin and neuropeptides ff and qrfp bind to their respective receptors
(R-RNO-389397)
Peptide ligand-binding receptors
(R-RNO-375276)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Cellular response to hormone stimulus
(GO:0032870)
Feeding behavior
(GO:0007631)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Neuropeptide signaling pathway
(GO:0007218)
Orexin receptor activity
(GO:0016499)
Peptide binding
(GO:0042277)
Peptide hormone binding
(GO:0017046)
Plasma membrane
(GO:0005886)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Regulation of cytosolic calcium ion concentration
(GO:0051480)

Other Information

Proteins

OX1R_RAT

Genular Protein ID: 4288417306

Symbol: OX1R_RAT

Name: N/A

UniProtKB Accession Codes:

P56718

Database IDs:

Citations:

PubMed ID: 9491897

Title: Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

PubMed ID: 9491897

DOI: 10.1016/s0092-8674(00)80949-6

PubMed ID: 11340621

Title: Hypocretin/orexin, sleep and narcolepsy.

PubMed ID: 11340621

DOI: 10.1002/bies.1058

PubMed ID: 11283317

Title: To eat or to sleep? Orexin in the regulation of feeding and wakefulness.

PubMed ID: 11283317

DOI: 10.1146/annurev.neuro.24.1.429

Sequence Information:

Length: 416
Mass: 46800
Checksum: 774DE7A22EA05D18
Sequence:

MEPSATPGAQ PGVPTSSGEP FHLPPDYEDE FLRYLWRDYL YPKQYEWVLI AAYVAVFLIA 
LVGNTLVCLA VWRNHHMRTV TNYFIVNLSL ADVLVTAICL PASLLVDITE SWLFGHALCK 
VIPYLQAVSV SVAVLTLSFI ALDRWYAICH PLLFKSTARR ARGSILGIWA VSLAVMVPQA 
AVMECSSVLP ELANRTRLFS VCDERWADEL YPKIYHSCFF FVTYLAPLGL MGMAYFQIFR 
KLWGPQIPGT TSALVRNWKR PSEQLEAQHQ GLCTEPQPRA RAFLAEVKQM RARRKTAKML 
MVVLLVFALC YLPISVLNVL KRVFGMFRQA SDREAVYACF TFSHWLVYAN SAANPIIYNF 
LSGKFREQFK AAFSCCLPGL GPSSSARHKS LSLQSRCSVS KVSEHVVLTT VTTVLS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.