Hcrtr2 | ENSRNOG00000011251 | NCBI 25605

Details for: Hcrtr2

Gene ID: 25605

Symbol: Hcrtr2

Ensembl ID: ENSRNOG00000011251

Description: hypocretin receptor 2

Associated with

Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (q) signalling events
(R-RNO-416476)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Orexin and neuropeptides ff and qrfp bind to their respective receptors
(R-RNO-389397)
Peptide ligand-binding receptors
(R-RNO-375276)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Cellular response to hormone stimulus
(GO:0032870)
Circadian sleep/wake cycle process
(GO:0022410)
Feeding behavior
(GO:0007631)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Locomotion
(GO:0040011)
Neuropeptide signaling pathway
(GO:0007218)
Orexin receptor activity
(GO:0016499)
Peptide binding
(GO:0042277)
Peptide hormone binding
(GO:0017046)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Regulation of circadian sleep/wake cycle, wakefulness
(GO:0010840)
Regulation of cytosolic calcium ion concentration
(GO:0051480)

Other Information

Proteins

Orexin receptor type 2

Genular Protein ID: 1062890138

Symbol: OX2R_RAT

Name: Orexin receptor type 2

UniProtKB Accession Codes:

P56719

Database IDs:

Citations:

PubMed ID: 9491897

Title: Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

PubMed ID: 9491897

DOI: 10.1016/s0092-8674(00)80949-6

PubMed ID: 11340621

Title: Hypocretin/orexin, sleep and narcolepsy.

PubMed ID: 11340621

DOI: 10.1002/bies.1058

PubMed ID: 11283317

Title: To eat or to sleep? Orexin in the regulation of feeding and wakefulness.

PubMed ID: 11283317

DOI: 10.1146/annurev.neuro.24.1.429

Sequence Information:

Length: 460
Mass: 52489
Checksum: 3B44E3D82F8B85D5
Sequence:

MSSTKLEDSL PRRNWSSASE LNETQEPFLN PTDYDDEEFL RYLWREYLHP KEYEWVLIAG 
YIIVFVVALI GNVLVCVAVW KNHHMRTVTN YFIVNLSLAD VLVTITCLPA TLVVDITETW 
FFGQSLCKVI PYLQTVSVSV SVLTLSCIAL DRWYAICHPL MFKSTAKRAR NSIVVIWIVS 
CIIMIPQAIV MERSSMLPGL ANKTTLFTVC DERWGGEVYP KMYHICFFLV TYMAPLCLMV 
LAYLQIFRKL WCRQIPGTSS VVQRKWKQPQ PVSQPRGSGQ QSKARISAVA AEIKQIRARR 
KTARMLMVVL LVFAICYLPI SILNVLKRVF GMFTHTEDRE TVYAWFTFSH WLVYANSAAN 
PIIYNFLSGK FREEFKAAFS CCLGVHRRQG DRLARGRTST ESRKSLTTQI SNFDNVSKLS 
EHVALTSIST LPAANGAGPL QNWYLQQGVP SSLLSTWLEV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.