Hspa5 | ENSRNOG00000018294 | NCBI 25617

Details for: Hspa5

Gene ID: 25617

Symbol: Hspa5

Ensembl ID: ENSRNOG00000018294

Description: heat shock protein family A (Hsp70) member 5

Associated with

Adaptive immune system
(R-RNO-1280218)
Antigen presentation: folding, assembly and peptide loading of class i mhc
(R-RNO-983170)
Cellular responses to stimuli
(R-RNO-8953897)
Cellular responses to stress
(R-RNO-2262752)
Cellular response to heat stress
(R-RNO-3371556)
Class i mhc mediated antigen processing & presentation
(R-RNO-983169)
Immune system
(R-RNO-168256)
Regulation of hsf1-mediated heat shock response
(R-RNO-3371453)
Atp-dependent protein folding chaperone
(GO:0140662)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cell surface
(GO:0009986)
Cellular response to antibiotic
(GO:0071236)
Cellular response to calcium ion
(GO:0071277)
Cellular response to camp
(GO:0071320)
Cellular response to gamma radiation
(GO:0071480)
Cellular response to glucose starvation
(GO:0042149)
Cellular response to interleukin-4
(GO:0071353)
Cellular response to manganese ion
(GO:0071287)
Cellular response to nerve growth factor stimulus
(GO:1990090)
Cellular response to xenobiotic stimulus
(GO:0071466)
Cerebellar purkinje cell layer development
(GO:0021680)
Cerebellum structural organization
(GO:0021589)
Chaperone cofactor-dependent protein refolding
(GO:0051085)
Cop9 signalosome
(GO:0008180)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendritic shaft
(GO:0043198)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum-golgi intermediate compartment
(GO:0005793)
Endoplasmic reticulum chaperone complex
(GO:0034663)
Endoplasmic reticulum lumen
(GO:0005788)
Endoplasmic reticulum membrane
(GO:0005789)
Endoplasmic reticulum unfolded protein response
(GO:0030968)
Enzyme binding
(GO:0019899)
Erad pathway
(GO:0036503)
Er overload response
(GO:0006983)
Heat shock protein binding
(GO:0031072)
Intracellular membrane-bounded organelle
(GO:0043231)
Ire1-mediated unfolded protein response
(GO:0036498)
Luteolysis
(GO:0001554)
Maintenance of protein localization in endoplasmic reticulum
(GO:0035437)
Melanosome
(GO:0042470)
Membrane
(GO:0016020)
Midbody
(GO:0030496)
Misfolded protein binding
(GO:0051787)
Mitochondrion
(GO:0005739)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of ire1-mediated unfolded protein response
(GO:1903895)
Negative regulation of protein-containing complex assembly
(GO:0031333)
Negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)
Neuronal cell body
(GO:0043025)
Neuron apoptotic process
(GO:0051402)
Neuron differentiation
(GO:0030182)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of neuron projection development
(GO:0010976)
Positive regulation of protein ubiquitination
(GO:0031398)
Post-translational protein targeting to membrane, translocation
(GO:0031204)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein folding
(GO:0006457)
Protein folding chaperone
(GO:0044183)
Protein refolding
(GO:0042026)
Proteolysis involved in protein catabolic process
(GO:0051603)
Response to cocaine
(GO:0042220)
Response to endoplasmic reticulum stress
(GO:0034976)
Response to methamphetamine hydrochloride
(GO:1904313)
Ribosome binding
(GO:0043022)
Smooth endoplasmic reticulum
(GO:0005790)
Stress response to metal ion
(GO:0097501)
Substantia nigra development
(GO:0021762)
Ubiquitin protein ligase binding
(GO:0031625)
Unfolded protein binding
(GO:0051082)

Other Information

Proteins

BIP_RAT

Genular Protein ID: 2157579494

Symbol: BIP_RAT

Name: N/A

UniProtKB Accession Codes:

P06761

Database IDs:

Citations:

PubMed ID: 3087629

Title: An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein.

PubMed ID: 3087629

DOI: 10.1016/0092-8674(86)90746-4

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3468506

Title: Rat gene encoding the 78-kDa glucose-regulated protein GRP78: its regulatory sequences and the effect of protein glycosylation on its expression.

PubMed ID: 3468506

DOI: 10.1073/pnas.84.3.680

PubMed ID: 3563495

Title: Steroidogenesis-activator polypeptide isolated from a rat Leydig cell tumor.

PubMed ID: 3563495

DOI: 10.1126/science.3563495

PubMed ID: 12475965

Title: A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.

PubMed ID: 12475965

DOI: 10.1091/mbc.e02-05-0311

PubMed ID: 12514190

Title: Cloning and characterization of a novel GRP78-binding protein in the rat brain.

PubMed ID: 12514190

DOI: 10.1074/jbc.m212083200

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 654
Mass: 72347
Checksum: 9D686C6484150108
Sequence:

MKFTVVAAAL LLLCAVRAEE EDKKEDVGTV VGIDLGTTYS CVGVFKNGRV EIIANDQGNR 
ITPSYVAFTP EGERLIGDAA KNQLTSNPEN TVFDAKRLIG RTWNDPSVQQ DIKFLPFKVV 
EKKTKPYIQV DIGGGQTKTF APEEISAMVL TKMKETAEAY LGKKVTHAVV TVPAYFNDAQ 
RQATKDAGTI AGLNVMRIIN EPTAAAIAYG LDKREGEKNI LVFDLGGGTF DVSLLTIDNG 
VFEVVATNGD THLGGEDFDQ RVMEHFIKLY KKKTGKDVRK DNRAVQKLRR EVEKAKRALS 
SQHQARIEIE SFFEGEDFSE TLTRAKFEEL NMDLFRSTMK PVQKVLEDSD LKKSDIDEIV 
LVGGSTRIPK IQQLVKEFFN GKEPSRGINP DEAVAYGAAV QAGVLSGDQD TGDLVLLDVC 
PLTLGIETVG GVMTKLIPRN TVVPTKKSQI FSTASDNQPT VTIKVYEGER PLTKDNHLLG 
TFDLTGIPPA PRGVPQIEVT FEIDVNGILR VTAEDKGTGN KNKITITNDQ NRLTPEEIER 
MVNDAEKFAE EDKKLKERID TRNELESYAY SLKNQIGDKE KLGGKLSPED KETMEKAVEE 
KIEWLESHQD ADIEDFKAKK KELEEIVQPI ISKLYGSGGP PPTGEEDTSE KDEL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hspa5

Associated with

Other Information

An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein. PubMed ID: 3087629

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Rat gene encoding the 78-kDa glucose-regulated protein GRP78: its regulatory sequences and the effect of protein glycosylation on its expression. PubMed ID: 3468506

Steroidogenesis-activator polypeptide isolated from a rat Leydig cell tumor. PubMed ID: 3563495

A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. PubMed ID: 12475965

Cloning and characterization of a novel GRP78-binding protein in the rat brain. PubMed ID: 12514190

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903