Ptpn11 | ENSRNOG00000030124 | NCBI 25622

Details for: Ptpn11

Gene ID: 25622

Symbol: Ptpn11

Ensembl ID: ENSRNOG00000030124

Description: protein tyrosine phosphatase, non-receptor type 11

Associated with

Atrioventricular canal development
(GO:0036302)
Axonogenesis
(GO:0007409)
Bergmann glial cell differentiation
(GO:0060020)
Brain development
(GO:0007420)
Cadherin binding
(GO:0045296)
Cell adhesion molecule binding
(GO:0050839)
Cellular response to angiotensin
(GO:1904385)
Cellular response to epidermal growth factor stimulus
(GO:0071364)
Cellular response to hydrogen peroxide
(GO:0070301)
Cellular response to insulin-like growth factor stimulus
(GO:1990314)
Cellular response to mechanical stimulus
(GO:0071260)
Cellular response to organic substance
(GO:0071310)
Cerebellar cortex formation
(GO:0021697)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
D1 dopamine receptor binding
(GO:0031748)
Dephosphorylation
(GO:0016311)
Dna damage checkpoint signaling
(GO:0000077)
Ephrin receptor signaling pathway
(GO:0048013)
Epidermal growth factor receptor signaling pathway
(GO:0007173)
Erbb signaling pathway
(GO:0038127)
Face morphogenesis
(GO:0060325)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Genitalia development
(GO:0048806)
Glucose homeostasis
(GO:0042593)
Heart development
(GO:0007507)
Homeostasis of number of cells within a tissue
(GO:0048873)
Hormone-mediated signaling pathway
(GO:0009755)
Hormone metabolic process
(GO:0042445)
Inner ear development
(GO:0048839)
Insulin receptor binding
(GO:0005158)
Insulin receptor substrate binding
(GO:0043560)
Integrin-mediated signaling pathway
(GO:0007229)
Intestinal epithelial cell migration
(GO:0061582)
Lipid metabolic process
(GO:0006629)
Megakaryocyte development
(GO:0035855)
Microvillus organization
(GO:0032528)
Molecular adaptor activity
(GO:0060090)
Multicellular organismal reproductive process
(GO:0048609)
Multicellular organism growth
(GO:0035264)
Negative regulation of cell adhesion mediated by integrin
(GO:0033629)
Negative regulation of chondrocyte differentiation
(GO:0032331)
Negative regulation of cortisol secretion
(GO:0051463)
Negative regulation of growth hormone secretion
(GO:0060125)
Negative regulation of hormone secretion
(GO:0046888)
Negative regulation of insulin secretion
(GO:0046676)
Negative regulation of type i interferon production
(GO:0032480)
Neurotrophin trk receptor signaling pathway
(GO:0048011)
Non-membrane spanning protein tyrosine phosphatase activity
(GO:0004726)
Nucleus
(GO:0005634)
Organ growth
(GO:0035265)
Peptide hormone receptor binding
(GO:0051428)
Phospholipase binding
(GO:0043274)
Phosphoprotein phosphatase activity
(GO:0004721)
Phosphotyrosine residue binding
(GO:0001784)
Plasma membrane raft
(GO:0044853)
Platelet-derived growth factor receptor signaling pathway
(GO:0048008)
Platelet formation
(GO:0030220)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of focal adhesion assembly
(GO:0051894)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of hormone secretion
(GO:0046887)
Positive regulation of insulin receptor signaling pathway
(GO:0046628)
Positive regulation of interferon-beta production
(GO:0032728)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of mitotic cell cycle
(GO:0045931)
Positive regulation of ossification
(GO:0045778)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Positive regulation of signal transduction
(GO:0009967)
Positive regulation of tumor necrosis factor production
(GO:0032760)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein dephosphorylation
(GO:0006470)
Protein domain specific binding
(GO:0019904)
Protein kinase binding
(GO:0019901)
Protein tyrosine kinase binding
(GO:1990782)
Protein tyrosine phosphatase activity
(GO:0004725)
Receptor tyrosine kinase binding
(GO:0030971)
Regulation of cell adhesion mediated by integrin
(GO:0033628)
Regulation of mapk cascade
(GO:0043408)
Regulation of protein-containing complex assembly
(GO:0043254)
Regulation of protein export from nucleus
(GO:0046825)
Signaling receptor complex adaptor activity
(GO:0030159)
Signal transduction
(GO:0007165)
Smooth muscle cell proliferation
(GO:0048659)
Triglyceride metabolic process
(GO:0006641)

Other Information

Proteins

Tyrosine-protein phosphatase non-receptor type 11

Genular Protein ID: 2503405471

Symbol: PTN11_RAT

Name: Tyrosine-protein phosphatase non-receptor type 11

UniProtKB Accession Codes:

P41499 Q62626

Database IDs:

Citations:

PubMed ID: 8048963

Title: Identification of protein-tyrosine phosphatases prevalent in adipocytes by molecular cloning.

PubMed ID: 8048963

DOI: 10.1006/bbrc.1994.2015

PubMed ID: 7512964

Title: RNA splicing regulates the activity of a SH2 domain-containing protein tyrosine phosphatase.

PubMed ID: 7512964

DOI: 10.1016/s0021-9258(17)32709-6

PubMed ID: 1382983

Title: Purification and characterization of a rat liver protein-tyrosine phosphatase with sequence similarity to src-homology region 2.

PubMed ID: 1382983

DOI: 10.1111/j.1432-1033.1992.tb17277.x

PubMed ID: 8810330

Title: Activation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain molecule.

PubMed ID: 8810330

DOI: 10.1074/jbc.271.41.25569

PubMed ID: 9062191

Title: A family of proteins that inhibit signalling through tyrosine kinase receptors.

PubMed ID: 9062191

DOI: 10.1038/386181a0

PubMed ID: 16885344

Title: ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice.

PubMed ID: 16885344

DOI: 10.1158/0008-5472.can-06-1193

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 593
Mass: 68033
Checksum: 3329F10F0F60AF48
Sequence:

MTSRRWFHPN ITGVEAENLL LTRGVDGSFL ARPSKSNPGD FTLSVRRNGA VTHIKIQNTG 
DYYDLYGGEK FATLAELVQY YMEHHGQLKE KNGDVIELKY PLNCADPTSE RWFHGHLSGK 
EAEKLLTEKG KHGSFLVRES QSHPGDFVLS VRTGDDKGES NDSKSKVTHV MIRCQELKYD 
VGGGERFDSL TDLVEHYKKN PMVETLGTVL QLKQPLNTTR INAAEIESRV RELSKLAETT 
DKVKQGFWEE FETLQQQECK LLYSRKEGQR QENKNKNRYK NILPFDHTRV VLHDGDPNEP 
VSDYINANII MPEFETKCNN SKPKKSYIAT QGCLQNTVND FWRMVFQENS RVIVMTTKEV 
ERGKSKCVKY WPDECALKEY GVMRVRNVRE SAAHDYTLRE LKLSKVGQGN TERTVWQYHF 
RTWPDHGVPS DPGGVLDFLE EVHHKQESIV DAGPVVVHCS AGIGRTGTFI VIDILIDIIR 
EKGVDCDIDV PKTIQMVRSQ RSGMVQTEAQ YRFIYMAVQH YIETLQRRIE EEQKSKRKGH 
EYTNIKYSLV DQTSGDQSPL PPCTPTPPCA EMREDSARVY ENVGLMQQQR SFR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ptpn11

Associated with

Other Information

Identification of protein-tyrosine phosphatases prevalent in adipocytes by molecular cloning. PubMed ID: 8048963

RNA splicing regulates the activity of a SH2 domain-containing protein tyrosine phosphatase. PubMed ID: 7512964

Purification and characterization of a rat liver protein-tyrosine phosphatase with sequence similarity to src-homology region 2. PubMed ID: 1382983

Activation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain molecule. PubMed ID: 8810330

A family of proteins that inhibit signalling through tyrosine kinase receptors. PubMed ID: 9062191

ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice. PubMed ID: 16885344

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903