Cma1 | ENSRNOG00000020563 | NCBI 25627

Details for: Cma1

Gene ID: 25627

Symbol: Cma1

Ensembl ID: ENSRNOG00000020563

Description: chymase 1

Associated with

Activation of matrix metalloproteinases
(R-RNO-1592389)
Degradation of the extracellular matrix
(R-RNO-1474228)
Extracellular matrix organization
(R-RNO-1474244)
Metabolism of angiotensinogen to angiotensins
(R-RNO-2022377)
Metabolism of proteins
(R-RNO-392499)
Peptide hormone metabolism
(R-RNO-2980736)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signaling by scf-kit
(R-RNO-1433557)
Signal transduction
(R-RNO-162582)
Basement membrane disassembly
(GO:0034769)
Cellular response to glucose stimulus
(GO:0071333)
Cytokine precursor processing
(GO:0140447)
Cytoplasm
(GO:0005737)
Cytoplasmic ribonucleoprotein granule
(GO:0036464)
Cytosol
(GO:0005829)
Endopeptidase activity
(GO:0004175)
Extracellular matrix disassembly
(GO:0022617)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Intracellular membrane-bounded organelle
(GO:0043231)
Midbrain development
(GO:0030901)
Peptidase activity
(GO:0008233)
Peptide binding
(GO:0042277)
Peptide metabolic process
(GO:0006518)
Positive regulation of angiogenesis
(GO:0045766)
Protein catabolic process
(GO:0030163)
Protein processing
(GO:0016485)
Regulation of inflammatory response
(GO:0050727)
Secretory granule
(GO:0030141)
Serine-type endopeptidase activity
(GO:0004252)
Serine-type peptidase activity
(GO:0008236)

Other Information

Proteins

Chymase

Genular Protein ID: 318776517

Symbol: CMA1_RAT

Name: Chymase

UniProtKB Accession Codes:

P50339 Q9R2C8

Database IDs:

Citations:

PubMed ID: 7487912

Title: Cloning of the cDNA encoding a novel rat mast-cell proteinase, rMCP-3, and its expression in comparison with other rat mast-cell proteinases.

PubMed ID: 7487912

DOI: 10.1042/bj3110675

PubMed ID: 8996238

Title: Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations.

PubMed ID: 8996238

DOI: 10.1084/jem.185.1.13

Sequence Information:

Length: 247
Mass: 27569
Checksum: 6525D7BF1BFDF053
Sequence:

MNLHALCLLL LLLGSSTKAG EIIGGTECIP HSRPYMAYLE IVTSDNYLSA CSGFLIRRNF 
VLTAAHCAGR SITVLLGAHN KTYKEDTWQK LEVEKQFIHP NYDKRLVLHD IMLLKLKEKA 
KLTLGVGTLP LSANFNFIPP GRMCRAVGWG RTNVNEPASD TLQEVKMRLQ EPQSCKHFTS 
FQHKSQLCVG NPKKMQNVYK GDSGGPLLCA GIAQGIASYV HPNAKPPAVF TRISHYRPWI 
NKILREN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.