Fkbp1a | ENSRNOG00000008822 | NCBI 25639

Details for: Fkbp1a

Gene ID: 25639

Symbol: Fkbp1a

Ensembl ID: ENSRNOG00000008822

Description: FKBP prolyl isomerase 1A

Associated with

Adaptive immune system
(R-RNO-1280218)
Calcineurin activates nfat
(R-RNO-2025928)
Downstream signaling events of b cell receptor (bcr)
(R-RNO-1168372)
Immune system
(R-RNO-168256)
Mtorc1-mediated signalling
(R-RNO-166208)
Mtor signalling
(R-RNO-165159)
Signaling by tgf-beta receptor complex
(R-RNO-170834)
Signaling by tgfb family members
(R-RNO-9006936)
Signaling by the b cell receptor (bcr)
(R-RNO-983705)
Signal transduction
(R-RNO-162582)
Tgf-beta receptor signaling activates smads
(R-RNO-2173789)
Activin receptor binding
(GO:0070697)
Amyloid fibril formation
(GO:1990000)
Axon terminus
(GO:0043679)
Calcium channel inhibitor activity
(GO:0019855)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytoplasm
(GO:0005737)
Cytoplasmic side of membrane
(GO:0098562)
Cytosol
(GO:0005829)
Enzyme binding
(GO:0019899)
Fk506 binding
(GO:0005528)
Heart morphogenesis
(GO:0003007)
Heart trabecula formation
(GO:0060347)
Hsp70 protein binding
(GO:0030544)
I-smad binding
(GO:0070411)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Muscle contraction
(GO:0006936)
Negative regulation of activin receptor signaling pathway
(GO:0032926)
Negative regulation of release of sequestered calcium ion into cytosol
(GO:0051280)
Negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)
Peptidyl-prolyl cis-trans isomerase activity
(GO:0003755)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Protein binding
(GO:0005515)
Protein peptidyl-prolyl isomerization
(GO:0000413)
Regulation of amyloid precursor protein catabolic process
(GO:1902991)
Regulation of immune response
(GO:0050776)
Regulation of protein localization
(GO:0032880)
Regulation of ryanodine-sensitive calcium-release channel activity
(GO:0060314)
Release of sequestered calcium ion into cytosol
(GO:0051209)
Response to caffeine
(GO:0031000)
Response to iron ion
(GO:0010039)
Ryanodine receptor complex
(GO:1990425)
Sarcoplasmic reticulum
(GO:0016529)
Sarcoplasmic reticulum membrane
(GO:0033017)
Signaling receptor inhibitor activity
(GO:0030547)
Supramolecular fiber organization
(GO:0097435)
Synapse
(GO:0045202)
T cell proliferation
(GO:0042098)
Transforming growth factor beta receptor binding
(GO:0005160)
Transmembrane transporter binding
(GO:0044325)
Type i transforming growth factor beta receptor binding
(GO:0034713)
Ventricular cardiac muscle tissue morphogenesis
(GO:0055010)
Z disc
(GO:0030018)

Other Information

Proteins

Peptidyl-prolyl cis-trans isomerase FKBP1A

Genular Protein ID: 2753964985

Symbol: FKB1A_RAT

Name: Peptidyl-prolyl cis-trans isomerase FKBP1A

UniProtKB Accession Codes:

Q62658 A0JN04 P97533

Database IDs:

Citations:

PubMed ID: 7518616

Title: Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12.

PubMed ID: 7518616

DOI: 10.1126/science.7518616

PubMed ID: 9013543

Title: Cyclic ADP-ribose binds to FK506-binding protein 12.6 to release Ca2+ from islet microsomes.

PubMed ID: 9013543

DOI: 10.1074/jbc.272.6.3133

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20431056

Title: Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks.

PubMed ID: 20431056

DOI: 10.1161/circresaha.110.219816

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 108
Mass: 11923
Checksum: 1C195C2A52C17666
Sequence:

MGVQVETISS GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFT LGKQEVIRGW 
EEGVAQMSVG QRAKLIISPD YAYGATGHPG IIPPHATLVF DVELLKLE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fkbp1a

Associated with

Other Information

Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12. PubMed ID: 7518616

Cyclic ADP-ribose binds to FK506-binding protein 12.6 to release Ca2+ from islet microsomes. PubMed ID: 9013543

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334