Details for: Otx1

Gene ID: 25646

Symbol: Otx1

Ensembl ID: ENSRNOG00000065081

Description: orthodenticle homeobox 1

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Diencephalon morphogenesis
    (GO:0048852)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Forebrain development
    (GO:0030900)
  • Inner ear morphogenesis
    (GO:0042472)
  • Metencephalon development
    (GO:0022037)
  • Midbrain development
    (GO:0030901)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)

Other Information

Genular Protein ID: 1598990559

Symbol: OTX1_RAT

Name: Homeobox protein OTX1

UniProtKB Accession Codes:

Q63410 Q64203

Database IDs:

AGR 1 AlphaFoldDB 1 CDD 1 CTD 1 EMBL 2 GO 13 Gene3D 1 InParanoid 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 UniProtKB 1

Citations:

PubMed ID: 7931541

Title: Otx1 and Otx2 define layers and regions in developing cerebral cortex and cerebellum.

PubMed ID: 7931541

DOI: 10.1523/jneurosci.14-10-05725.1994

PubMed ID: 8613727

Title: Fibroblast growth factor 2 increases Otx2 expression in precursor cells from mammalian telencephalon.

PubMed ID: 8613727

DOI: 10.1523/jneurosci.15-12-07879.1995

Sequence Information:

  • Length: 355
  • Mass: 37603
  • Checksum: C875871723D0B876
  • Sequence:
    • MMSYLKQPPY GMNGLGLAGP AMDLLHPSVG YPATPRKQRR ERTTFTRSQL DVLEALFAKT 
RYPDIFMREE VALKINLPES RVQVWFKNRR AKCRQQQQSG NGTKSRPVKK KSSPVRESSG 
SESSGQFTPP AVSSSASSSS SASSASANPA AAAAAGLGGN PVAAASSLST PTASSIWSPA 
SISPGSAPAS VSVPEPLGAP SNASCMQRSV AAGAATAATS YPMSYGQGRS YGQGYPAPSS 
SYFGGVDCSS YLAPMHSHHH PHQLSPMAPS SMAGHHHHHP HAHHPLSQSS GHHHHHHHHH 
HHQGYGGSGL AFNSADCLDY KEPAAAAASS AWKLNFNSPD CLDYKDQASW RFQVL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.