Pparg | ENSRNOG00000008839 | NCBI 25664

Details for: Pparg

Gene ID: 25664

Symbol: Pparg

Ensembl ID: ENSRNOG00000008839

Description: peroxisome proliferator-activated receptor gamma

Associated with

Developmental biology
(R-RNO-1266738)
Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Nuclear receptor transcription pathway
(R-RNO-383280)
Rna polymerase ii transcription
(R-RNO-73857)
Transcriptional regulation of white adipocyte differentiation
(R-RNO-381340)
Alpha-actinin binding
(GO:0051393)
Animal organ regeneration
(GO:0031100)
Arachidonic acid binding
(GO:0050544)
Bmp signaling pathway
(GO:0030509)
Cell differentiation
(GO:0030154)
Cell population proliferation
(GO:0008283)
Cellular response to insulin stimulus
(GO:0032869)
Chromatin binding
(GO:0003682)
Diet induced thermogenesis
(GO:0002024)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor binding
(GO:0140297)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Dna binding domain binding
(GO:0050692)
Double-stranded dna binding
(GO:0003690)
E-box binding
(GO:0070888)
Enzyme binding
(GO:0019899)
Epithelial cell differentiation
(GO:0030855)
Fatty acid metabolic process
(GO:0006631)
Fatty acid oxidation
(GO:0019395)
Heart development
(GO:0007507)
Hormone-mediated signaling pathway
(GO:0009755)
Identical protein binding
(GO:0042802)
Lbd domain binding
(GO:0050693)
Long-chain fatty acid transport
(GO:0015909)
Macrophage derived foam cell differentiation
(GO:0010742)
Monocyte differentiation
(GO:0030224)
Negative regulation of acute inflammatory response
(GO:0002674)
Negative regulation of angiogenesis
(GO:0016525)
Negative regulation of bmp signaling pathway
(GO:0030514)
Negative regulation of cell growth
(GO:0030308)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of cholesterol storage
(GO:0010887)
Negative regulation of collagen biosynthetic process
(GO:0032966)
Negative regulation of cytokine production
(GO:0001818)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of lipid storage
(GO:0010888)
Negative regulation of macrophage derived foam cell differentiation
(GO:0010745)
Negative regulation of sequestering of triglyceride
(GO:0010891)
Negative regulation of smooth muscle cell migration
(GO:0014912)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)
Nuclear estrogen receptor binding
(GO:0030331)
Nuclear receptor activity
(GO:0004879)
Nuclear receptor coactivator activity
(GO:0030374)
Nuclear retinoid x receptor binding
(GO:0046965)
Nucleic acid binding
(GO:0003676)
Peptide binding
(GO:0042277)
Placenta development
(GO:0001890)
Positive regulation of cholesterol efflux
(GO:0010875)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of intracellular cholesterol transport
(GO:0032385)
Positive regulation of prostaglandin biosynthetic process
(GO:0031394)
Promoter-specific chromatin binding
(GO:1990841)
Protein binding
(GO:0005515)
Protein phosphatase binding
(GO:0019903)
Protein self-association
(GO:0043621)
R-smad binding
(GO:0070412)
Regulation of blood pressure
(GO:0008217)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of gene expression
(GO:0010468)
Regulation of lipid metabolic process
(GO:0019216)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to caffeine
(GO:0031000)
Response to dietary excess
(GO:0002021)
Response to food
(GO:0032094)
Response to light stimulus
(GO:0009416)
Response to lipid
(GO:0033993)
Response to mechanical stimulus
(GO:0009612)
Response to organic cyclic compound
(GO:0014070)
Response to organic substance
(GO:0010033)
Response to vitamin a
(GO:0033189)
Response to xenobiotic stimulus
(GO:0009410)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii core promoter sequence-specific dna binding
(GO:0000979)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Sequence-specific dna binding
(GO:0043565)
Signal transduction
(GO:0007165)
Stat family protein binding
(GO:0097677)
Transcription cis-regulatory region binding
(GO:0000976)
Transcription coactivator binding
(GO:0001223)
Transcription coregulator binding
(GO:0001221)
Wound healing involved in inflammatory response
(GO:0002246)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Peroxisome proliferator-activated receptor gamma
A6IKY4_RAT

Genular Protein ID: 2538699777

Symbol: PPARG_RAT

Name: Peroxisome proliferator-activated receptor gamma

UniProtKB Accession Codes:

O88275 Q9QWG0 Q9R197

Database IDs:

Citations:

PubMed ID: 10438514

Title: Rat peroxisome proliferator-activated receptors and brown adipose tissue function during cold acclimatization.

PubMed ID: 10438514

DOI: 10.1074/jbc.274.33.23368

PubMed ID: 10797535

Title: Photoreceptor phagocytosis selectively activates PPARgamma expression in retinal pigment epithelial cells.

PubMed ID: 10797535

DOI: 10.1002/(sici)1097-4547(20000501)60:3<328::aid-jnr7>3.0.co;2-5

PubMed ID: 8953045

Title: Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma.

PubMed ID: 8953045

DOI: 10.1126/science.274.5295.2100

PubMed ID: 9030579

Title: Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site.

PubMed ID: 9030579

DOI: 10.1074/jbc.272.8.5128

PubMed ID: 8943212

Title: Insulin- and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferator-activated receptor gamma.

PubMed ID: 8943212

DOI: 10.1074/jbc.271.50.31771

Sequence Information:

Length: 505
Mass: 57567
Checksum: F16E5CAB122EBB32
Sequence:

MGETLGDPPV DPEHGAFADA LPMSTSQEIT MVDTEMPFWP TNFGISSVDL SVMDDHSHSF 
DIKPFTTVDF SSISAPHYED IPFTRADPMV ADYKYDLKLQ EYQSAIKVEP ASPPYYSEKT 
QLYNRPHEEP SNSLMAIECR VCGDKASGFH YGVHACEGCK GFFRRTIRLK LIYDRCDLNC 
RIHKKSRNKC QYCRFQKCLA VGMSHNAIRF GRMPQAEKEK LLAEISSDID QLNPESADLR 
ALAKHLYDSY IKSFPLTKAK ARAILTGKTT DKSPFVIYDM NSLMMGEDKI KFKHITPLQE 
QSKEVAIRIF QGCQFRSVEA VQEITEYAKN IPGFINLDLN DQVTLLKYGV HEIIYTMLAS 
LMNKDGVLIS EGQGFMTREF LKSLRKPFGD FMEPKFEFAV KFNALELDDS DLAIFIAVII 
LSGDRPGLLN VKPIEDIQDN LLQALELQLK LNHPESSQLF AKVLQKMTDL RQIVTEHVQL 
LHVIKKTETD MSLHPLLQEI YKDLY

Genular Protein ID: 2921677793

Symbol: A6IKY4_RAT

Name: N/A

UniProtKB Accession Codes:

A6IKY4

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 475
Mass: 54471
Checksum: C761352FDF9C4395
Sequence:

MVDTEMPFWP TNFGISSVDL SVMDDHSHSF DIKPFTTVDF SSISAPHYED IPFTRADPMV 
ADYKYDLKLQ EYQSAIKVEP ASPPYYSEKT QLYNRPHEEP SNSLMAIECR VCGDKASGFH 
YGVHACEGCK GFFRRTIRLK LIYDRCDLNC RIHKKSRNKC QYCRFQKCLA VGMSHNAIRF 
GRMPQAEKEK LLAEISSDID QLNPESADLR ALAKHLYDSY IKSFPLTKAK ARAILTGKTT 
DKSPFVIYDM NSLMMGEDKI KFKHITPLQE QSKEVAIRIF QGCQFRSVEA VQEITEYAKN 
IPGFINLDLN DQVTLLKYGV HEIIYTMLAS LMNKDGVLIS EGQGFMTREF LKSLRKPFGD 
FMEPKFEFAV KFNALELDDS DLAIFIAVII LSGDRPGLLN VKPIEDIQDN LLQALELQLK 
LNHPESSQLF AKVLQKMTDL RQIVTEHVQL LHVIKKTETD MSLHPLLQEI YKDLY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pparg

Associated with

Other Information

Rat peroxisome proliferator-activated receptors and brown adipose tissue function during cold acclimatization. PubMed ID: 10438514

Photoreceptor phagocytosis selectively activates PPARgamma expression in retinal pigment epithelial cells. PubMed ID: 10797535

Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma. PubMed ID: 8953045

Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. PubMed ID: 9030579

Insulin- and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferator-activated receptor gamma. PubMed ID: 8943212