Nr3c2 | ENSRNOG00000034007 | NCBI 25672

Details for: Nr3c2

Gene ID: 25672

Symbol: Nr3c2

Ensembl ID: ENSRNOG00000034007

Description: nuclear receptor subfamily 3, group C, member 2

Associated with

Cellular responses to stimuli
(R-RNO-8953897)
Cellular responses to stress
(R-RNO-2262752)
Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Hsp90 chaperone cycle for steroid hormone receptors (shr) in the presence of ligand
(R-RNO-3371497)
Metabolism of proteins
(R-RNO-392499)
Nuclear receptor transcription pathway
(R-RNO-383280)
Post-translational protein modification
(R-RNO-597592)
Rna polymerase ii transcription
(R-RNO-73857)
Sumo e3 ligases sumoylate target proteins
(R-RNO-3108232)
Sumoylation
(R-RNO-2990846)
Sumoylation of intracellular receptors
(R-RNO-4090294)
Angiotensin-activated signaling pathway
(GO:0038166)
Cellular response to aldosterone
(GO:1904045)
Dna-binding transcription factor activity
(GO:0003700)
Double-stranded dna binding
(GO:0003690)
Endoplasmic reticulum membrane
(GO:0005789)
Estrogen response element binding
(GO:0034056)
Gaba-ergic synapse
(GO:0098982)
Glutamatergic synapse
(GO:0098978)
Histone acetyltransferase binding
(GO:0035035)
Identical protein binding
(GO:0042802)
Intracellular sodium ion homeostasis
(GO:0006883)
Intracellular steroid hormone receptor signaling pathway
(GO:0030518)
Nuclear receptor activity
(GO:0004879)
Nuclear steroid receptor activity
(GO:0003707)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of non-canonical nf-kappab signal transduction
(GO:1901224)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Postsynaptic density, intracellular component
(GO:0099092)
Potassium ion homeostasis
(GO:0055075)
Presynaptic active zone cytoplasmic component
(GO:0098831)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Receptor complex
(GO:0043235)
Regulation of blood volume by renal aldosterone
(GO:0002017)
Regulation of cell population proliferation
(GO:0042127)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of postsynaptic membrane potential
(GO:0060078)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Renal sodium excretion
(GO:0035812)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Signal transduction
(GO:0007165)
Steroid binding
(GO:0005496)
Tbp-class protein binding
(GO:0017025)
Transcription coactivator binding
(GO:0001223)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Mineralocorticoid receptor

Genular Protein ID: 1875270310

Symbol: MCR_RAT

Name: Mineralocorticoid receptor

UniProtKB Accession Codes:

P22199 Q63763 Q64174

Database IDs:

Citations:

PubMed ID: 2558305

Title: Molecular cloning of a mineralocorticoid (type I) receptor complementary DNA from rat hippocampus.

PubMed ID: 2558305

DOI: 10.1210/mend-3-11-1877

PubMed ID: 7495694

Title: Identification of a splice variant of the rat and human mineralocorticoid receptor genes.

PubMed ID: 7495694

DOI: 10.1016/0960-0760(95)00162-s

PubMed ID: 7982810

Title: Mineralocorticoid type I receptor in the rat cochlea: mRNA identification by polymerase chain reaction (PCR) and in situ hybridization.

PubMed ID: 7982810

DOI: 10.1016/0378-5955(94)90023-x

PubMed ID: 8618925

Title: Steroid receptor heterodimerization demonstrated in vitro and in vivo.

PubMed ID: 8618925

DOI: 10.1073/pnas.92.26.12480

PubMed ID: 9111344

Title: GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors.

PubMed ID: 9111344

DOI: 10.1128/mcb.17.5.2735

PubMed ID: 9677313

Title: Native rat kidney mineralocorticoid receptor is a phosphoprotein whose transformation to a DNA-binding form is induced by phosphatases.

PubMed ID: 9677313

DOI: 10.1042/bj3330555

PubMed ID: 10687858

Title: An alternatively spliced rat mineralocorticoid receptor mRNA causing truncation of the steroid binding domain.

PubMed ID: 10687858

DOI: 10.1016/s0303-7207(99)00198-7

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 981
Mass: 106737
Checksum: 184F5D37C1B030F7
Sequence:

METKGYHSLP EGLDMERRWS QVSQTLERSS LGPAERTTEN NYMEIVNVSC VSGAIPNNST 
QGSSKEKHEL LPYIQQDNSR SGILPSDIKT ELESKELSAT VAESMGLYMD SVRDAEYTYD 
QQNQQGSLSP TKIYQNMEQL VKFYKENGHR SSTLSAMSRP LRSFMPDSAA SMNGGALRAI 
VKSPIICHEK SSSVSSPLNM ASSVCSPVGI NSMSSSTTSF GSFPVHSPIT QGTSLTCSPS 
VENRGSRSHS PTHASNVGSP LSSPLSSMKS PISSPPSHCS VKSPVSSPNN VPLRSSVSSP 
ANLNNSRCSV SSPSNNTNNR STLSSPTAST VGSIGSPISN AFSYATSGAS AGAGAIQDVV 
PSPDTHEKGA HDVPFPKTEE VEKAISNGVT GPLNIVQYIK SEPDGAFSSS CLGGNSKISP 
SSPFSVPIKQ ESSKHSCSGA SFKGNPTVNP FPFMDGSYFS FMDDKDYYSL SGILGPPVPG 
FDGSCEDSAF PVGIKQEPDD GSYYPEASIP SSAIVGVNSG GQSFHYRIGA QGTISLSRSP 
RDQSFQHLSS FPPVNTLVES WKPHGDLSSR RSDGYPVLEY IPENVSSSTL RSVSTGSSRP 
SKICLVCGDE ASGCHYGVVT CGSCKVFFKR AVEGQHNYLC AGRNDCIIDK IRRKNCPACR 
LQKCLQAGMN LGARKSKKLG KLKGLHEEQP QQPPPPPPQS PEEGTTYIAP TKEPSVNSAL 
VPQLTSITHA LTPSPAMILE NIEPETVYAG YDNSKPDTAE SLLSTLNRLA AKQMIQVVKW 
AKVLPGFKNL PLEDQITLIQ YSWMCLSSFA LSWRSYKHTN SQLLYFAPDL VFNEEKMHQS 
AMYELCQGMR QISLQFVRLQ LTFEEYSIMK VLLLLSTVPK DGLKSQAAFE EMRTNYIKEL 
RKMVTKCPNS SGQSWQRFYQ LTKLLDSMHD LVSDLLEFCF YTFRESQALK VEFPAMLVEI 
ITDQLPKVES GNAKPLYFHR K

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nr3c2

Associated with

Other Information

Molecular cloning of a mineralocorticoid (type I) receptor complementary DNA from rat hippocampus. PubMed ID: 2558305

Identification of a splice variant of the rat and human mineralocorticoid receptor genes. PubMed ID: 7495694

Mineralocorticoid type I receptor in the rat cochlea: mRNA identification by polymerase chain reaction (PCR) and in situ hybridization. PubMed ID: 7982810

Steroid receptor heterodimerization demonstrated in vitro and in vivo. PubMed ID: 8618925

GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors. PubMed ID: 9111344

Native rat kidney mineralocorticoid receptor is a phosphoprotein whose transformation to a DNA-binding form is induced by phosphatases. PubMed ID: 9677313

An alternatively spliced rat mineralocorticoid receptor mRNA causing truncation of the steroid binding domain. PubMed ID: 10687858

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903