Details for: Ifng

Gene ID: 25712

Symbol: Ifng

Ensembl ID: ENSRNOG00000007468

Description: interferon gamma

Associated with

  • Cytokine signaling in immune system
    (R-RNO-1280215)
  • Ifng signaling activates mapks
    (R-RNO-9732724)
  • Immune system
    (R-RNO-168256)
  • Interferon gamma signaling
    (R-RNO-877300)
  • Interferon signaling
    (R-RNO-913531)
  • Regulation of ifng signaling
    (R-RNO-877312)
  • Adaptive immune response
    (GO:0002250)
  • Antigen processing and presentation
    (GO:0019882)
  • Apoptotic process
    (GO:0006915)
  • Astrocyte activation
    (GO:0048143)
  • Cd8-positive, alpha-beta t cell differentiation involved in immune response
    (GO:0002302)
  • Cellular response to interleukin-18
    (GO:0071351)
  • Cellular response to lipopolysaccharide
    (GO:0071222)
  • Cytokine activity
    (GO:0005125)
  • Defense response to bacterium
    (GO:0042742)
  • Defense response to gram-positive bacterium
    (GO:0050830)
  • Defense response to protozoan
    (GO:0042832)
  • Defense response to virus
    (GO:0051607)
  • Endoplasmic reticulum unfolded protein response
    (GO:0030968)
  • Humoral immune response
    (GO:0006959)
  • Inflammatory cell apoptotic process
    (GO:0006925)
  • Macrophage activation involved in immune response
    (GO:0002281)
  • Macrophage differentiation
    (GO:0030225)
  • Microglial cell activation
    (GO:0001774)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of epithelial cell differentiation
    (GO:0030857)
  • Negative regulation of fibroblast proliferation
    (GO:0048147)
  • Negative regulation of gene expression
    (GO:0010629)
  • Negative regulation of glomerular mesangial cell proliferation
    (GO:0072125)
  • Negative regulation of interleukin-17 production
    (GO:0032700)
  • Negative regulation of myelination
    (GO:0031642)
  • Negative regulation of osteoclast differentiation
    (GO:0045671)
  • Negative regulation of smooth muscle cell proliferation
    (GO:0048662)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neutrophil apoptotic process
    (GO:0001781)
  • Neutrophil chemotaxis
    (GO:0030593)
  • Nitric oxide biosynthetic process
    (GO:0006809)
  • Positive regulation by host of viral process
    (GO:0044794)
  • Positive regulation of apoptotic process
    (GO:0043065)
  • Positive regulation of autophagy
    (GO:0010508)
  • Positive regulation of cd4-positive, cd25-positive, alpha-beta regulatory t cell differentiation involved in immune response
    (GO:0032834)
  • Positive regulation of cell adhesion
    (GO:0045785)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of chemokine production
    (GO:0032722)
  • Positive regulation of cytokine production
    (GO:0001819)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of epithelial cell migration
    (GO:0010634)
  • Positive regulation of fructose 1,6-bisphosphate metabolic process
    (GO:0060552)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of glycolytic process
    (GO:0045821)
  • Positive regulation of inflammatory response
    (GO:0050729)
  • Positive regulation of interleukin-1 beta production
    (GO:0032731)
  • Positive regulation of interleukin-6 production
    (GO:0032755)
  • Positive regulation of interleukin-12 production
    (GO:0032735)
  • Positive regulation of interleukin-23 production
    (GO:0032747)
  • Positive regulation of isotype switching to igg isotypes
    (GO:0048304)
  • Positive regulation of killing of cells of another organism
    (GO:0051712)
  • Positive regulation of macrophage cytokine production
    (GO:0060907)
  • Positive regulation of membrane protein ectodomain proteolysis
    (GO:0051044)
  • Positive regulation of mhc class ii biosynthetic process
    (GO:0045348)
  • Positive regulation of neurogenesis
    (GO:0050769)
  • Positive regulation of neuron differentiation
    (GO:0045666)
  • Positive regulation of nitric-oxide synthase biosynthetic process
    (GO:0051770)
  • Positive regulation of nitric oxide biosynthetic process
    (GO:0045429)
  • Positive regulation of nitrogen compound metabolic process
    (GO:0051173)
  • Positive regulation of osteoclast differentiation
    (GO:0045672)
  • Positive regulation of peptidyl-serine phosphorylation of stat protein
    (GO:0033141)
  • Positive regulation of phagocytosis
    (GO:0050766)
  • Positive regulation of protein-containing complex assembly
    (GO:0031334)
  • Positive regulation of protein deacetylation
    (GO:0090312)
  • Positive regulation of protein import into nucleus
    (GO:0042307)
  • Positive regulation of smooth muscle cell apoptotic process
    (GO:0034393)
  • Positive regulation of synaptic transmission, cholinergic
    (GO:0032224)
  • Positive regulation of t cell proliferation
    (GO:0042102)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Positive regulation of tumor necrosis factor production
    (GO:0032760)
  • Positive regulation of tyrosine phosphorylation of stat protein
    (GO:0042531)
  • Positive regulation of vitamin d biosynthetic process
    (GO:0060557)
  • Receptor signaling pathway via jak-stat
    (GO:0007259)
  • Regulation of defense response to virus by host
    (GO:0050691)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of glial cell proliferation
    (GO:0060251)
  • Regulation of immune response
    (GO:0050776)
  • Regulation of insulin secretion
    (GO:0050796)
  • Regulation of the force of heart contraction
    (GO:0002026)
  • Response to virus
    (GO:0009615)
  • Response to xenobiotic stimulus
    (GO:0009410)
  • Sensory perception of mechanical stimulus
    (GO:0050954)
  • T cell proliferation
    (GO:0042098)
  • T cell receptor signaling pathway
    (GO:0050852)
  • Type iii interferon-mediated signaling pathway
    (GO:0038196)
  • Type ii interferon-mediated signaling pathway
    (GO:0060333)
  • Type ii interferon receptor binding
    (GO:0005133)

Other Information

Genular Protein ID: 4033065113

Symbol: IFNG_RAT

Name: Interferon gamma

UniProtKB Accession Codes:

P01581

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 CTD 1 EMBL 8 Ensembl 4 GO 100 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 3 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 2 eggNOG 1

Citations:

PubMed ID: 3924594

Title: Cloning and expression of the chromosomal immune interferon gene of the rat.

PubMed ID: 3924594

DOI: 10.1002/j.1460-2075.1985.tb03694.x

PubMed ID: 3093809

Title: Cloning, expression, and purification of rat IFN-gamma.

PubMed ID: 3093809

DOI: 10.1016/0076-6879(86)19065-3

Sequence Information:

  • Length: 156
  • Mass: 17918
  • Checksum: BC0B433D2CE1E3F2
  • Sequence:
    • MSATRRVLVL QLCLMALSGC YCQGTLIESL ESLKNYFNSS SMDAMEGKSL LLDIWRNWQK 
DGNTKILESQ IISFYLRLFE VLKDNQAISN NISVIESHLI TNFFSNSKAK KDAFMSIAKF 
EVNNPQIQHK AVNELIRVIH QLSPESSLRK RKRSRC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.