Details for: Syt1
Associated with
Other Information
Genular Protein ID: 3721810776
Symbol: SYT1_RAT
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2333096
Title: Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C.
PubMed ID: 2333096
DOI: 10.1038/345260a0
PubMed ID: 15238157
Title: Synaptotagmin gene content of the sequenced genomes.
PubMed ID: 15238157
PubMed ID: 8144634
Title: Identification of protein receptor for Clostridium botulinum type B neurotoxin in rat brain synaptosomes.
PubMed ID: 8144634
PubMed ID: 1985919
Title: Domain structure of synaptotagmin (p65).
PubMed ID: 1985919
PubMed ID: 8910372
Title: Isoform-specific, calcium-regulated interaction of the synaptic vesicle proteins SV2 and synaptotagmin.
PubMed ID: 8910372
PubMed ID: 9867811
Title: Calcium-dependent oligomerization of synaptotagmins I and II. Synaptotagmins I and II are localized on the same synaptic vesicle and heterodimerize in the presence of calcium.
PubMed ID: 9867811
DOI: 10.1074/jbc.274.1.59
PubMed ID: 11438518
Title: Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin.
PubMed ID: 11438518
PubMed ID: 11931641
Title: Phosphorylation-dependent interaction of the synaptic vesicle proteins cysteine string protein and synaptotagmin I.
PubMed ID: 11931641
DOI: 10.1042/bj20020123
PubMed ID: 11823420
Title: Synaptotagmins form a hierarchy of exocytotic Ca(2+) sensors with distinct Ca(2+) affinities.
PubMed ID: 11823420
PubMed ID: 12782290
Title: Palmitoylation sites and processing of synaptotagmin I, the putative calcium sensor for neurosecretion.
PubMed ID: 12782290
PubMed ID: 14504267
Title: Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells.
PubMed ID: 14504267
PubMed ID: 15123599
Title: Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.
PubMed ID: 15123599
PubMed ID: 15866046
Title: SV2A and SV2C contain a unique synaptotagmin-binding site.
PubMed ID: 15866046
PubMed ID: 17167421
Title: Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.
PubMed ID: 17167421
DOI: 10.1038/nature05387
PubMed ID: 17167418
Title: Structural basis of cell surface receptor recognition by botulinum neurotoxin B.
PubMed ID: 17167418
DOI: 10.1038/nature05411
PubMed ID: 17190793
Title: Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release.
PubMed ID: 17190793
PubMed ID: 20219474
Title: Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding.
PubMed ID: 20219474
PubMed ID: 22673903
Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
PubMed ID: 22673903
DOI: 10.1038/ncomms1871
PubMed ID: 7697723
Title: Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold.
PubMed ID: 7697723
PubMed ID: 9819203
Title: Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?
PubMed ID: 9819203
DOI: 10.1021/bi981789h
PubMed ID: 11754837
Title: Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.
PubMed ID: 11754837
PubMed ID: 25964652
Title: The juxtamembrane region of synaptotagmin 1 interacts with dynamin 1 and regulates vesicle fission during compensatory endocytosis in endocrine cells.
PubMed ID: 25964652
DOI: 10.1242/jcs.161505
PubMed ID: 25705886
Title: Identification of a human synaptotagmin-1 mutation that perturbs synaptic vesicle cycling.
PubMed ID: 25705886
DOI: 10.1172/jci79765
PubMed ID: 28057568
Title: Localization of Rab3A-binding site on C2A domain of synaptotagmin I to reveal its regulatory mechanism.
PubMed ID: 28057568
PubMed ID: 30107533
Title: SYT1-associated neurodevelopmental disorder: a case series.
PubMed ID: 30107533
DOI: 10.1093/brain/awy209
Sequence Information:
- Length: 421
- Mass: 47399
- Checksum: 06CE28F04C97A722
- Sequence:
MVSASHPEAL AAPVTTVATL VPHNATEPAS PGEGKEDAFS KLKQKFMNEL HKIPLPPWAL IAIAIVAVLL VVTCCFCVCK KCLFKKKNKK KGKEKGGKNA INMKDVKDLG KTMKDQALKD DDAETGLTDG EEKEEPKEEE KLGKLQYSLD YDFQNNQLLV GIIQAAELPA LDMGGTSDPY VKVFLLPDKK KKFETKVHRK TLNPVFNEQF TFKVPYSELG GKTLVMAVYD FDRFSKHDII GEFKVPMNTV DFGHVTEEWR DLQSAEKEEQ EKLGDICFSL RYVPTAGKLT VVILEAKNLK KMDVGGLSDP YVKIHLMQNG KRLKKKKTTI KKNTLNPYYN ESFSFEVPFE QIQKVQVVVT VLDYDKIGKN DAIGKVFVGY NSTGAELRHW SDMLANPRRP IAQWHTLQVE EEVDAMLAVK K
Genular Protein ID: 2922309408
Symbol: Q707P0_RAT
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 113
- Mass: 12186
- Checksum: 93014B9FBA2596D8
- Sequence:
MVSASHPEAL AAPVTTVATL VPHNATEPAS PGEGKEDAFS KLKQKFMNEL HKIPLPPWAL IAIAIVAVLL VVTCCFCVCK KCLFKKKNKK KGKEKGGKNA INMKDVKDLG KTM
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.