Tgfb3 | ENSRNOG00000009867 | NCBI 25717

Details for: Tgfb3

Gene ID: 25717

Symbol: Tgfb3

Ensembl ID: ENSRNOG00000009867

Description: transforming growth factor, beta 3

Associated with

Elastic fibre formation
(R-RNO-1566948)
Extracellular matrix organization
(R-RNO-1474244)
Hemostasis
(R-RNO-109582)
Molecules associated with elastic fibres
(R-RNO-2129379)
Platelet activation, signaling and aggregation
(R-RNO-76002)
Platelet degranulation
(R-RNO-114608)
Response to elevated platelet cytosolic ca2+
(R-RNO-76005)
Signaling by tgf-beta receptor complex
(R-RNO-170834)
Signaling by tgfb family members
(R-RNO-9006936)
Signal transduction
(R-RNO-162582)
Tgf-beta receptor signaling activates smads
(R-RNO-2173789)
Animal organ morphogenesis
(GO:0009887)
Cell-cell junction organization
(GO:0045216)
Cell population proliferation
(GO:0008283)
Cell surface
(GO:0009986)
Cellular response to growth factor stimulus
(GO:0071363)
Collagen-containing extracellular matrix
(GO:0062023)
Cytokine activity
(GO:0005125)
Detection of hypoxia
(GO:0070483)
Digestive tract development
(GO:0048565)
Embryonic neurocranium morphogenesis
(GO:0048702)
Epithelial cell proliferation
(GO:0050673)
Extracellular matrix
(GO:0031012)
Extracellular space
(GO:0005615)
Face morphogenesis
(GO:0060325)
Female pregnancy
(GO:0007565)
Filopodium assembly
(GO:0046847)
Frontal suture morphogenesis
(GO:0060364)
Gene expression
(GO:0010467)
Growth factor activity
(GO:0008083)
Identical protein binding
(GO:0042802)
Inner ear development
(GO:0048839)
Intracellular membrane-bounded organelle
(GO:0043231)
In utero embryonic development
(GO:0001701)
Lung alveolus development
(GO:0048286)
Lung development
(GO:0030324)
Mammary gland development
(GO:0030879)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of epithelial cell proliferation
(GO:0050680)
Negative regulation of macrophage cytokine production
(GO:0010936)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)
Negative regulation of vascular associated smooth muscle cell proliferation
(GO:1904706)
Neuronal cell body
(GO:0043025)
Neuron apoptotic process
(GO:0051402)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cell division
(GO:0051781)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of collagen biosynthetic process
(GO:0032967)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of epithelial to mesenchymal transition
(GO:0010718)
Positive regulation of filopodium assembly
(GO:0051491)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of protein secretion
(GO:0050714)
Positive regulation of smad protein signal transduction
(GO:0060391)
Positive regulation of stress fiber assembly
(GO:0051496)
Positive regulation of tight junction disassembly
(GO:1905075)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-containing complex binding
(GO:0044877)
Regulation of cell population proliferation
(GO:0042127)
Regulation of endothelial cell differentiation
(GO:0045601)
Regulation of epithelial cell differentiation
(GO:0030856)
Regulation of epithelial cell proliferation
(GO:0050678)
Regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
(GO:1905005)
Response to estrogen
(GO:0043627)
Response to hypoxia
(GO:0001666)
Response to laminar fluid shear stress
(GO:0034616)
Response to progesterone
(GO:0032570)
Roof of mouth development
(GO:0060021)
Salivary gland morphogenesis
(GO:0007435)
Secondary palate development
(GO:0062009)
Secretory granule
(GO:0030141)
T-tubule
(GO:0030315)
Transforming growth factor beta binding
(GO:0050431)
Transforming growth factor beta receptor binding
(GO:0005160)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)
Type iii transforming growth factor beta receptor binding
(GO:0034714)
Type ii transforming growth factor beta receptor binding
(GO:0005114)
Type i transforming growth factor beta receptor binding
(GO:0034713)

Other Information

Proteins

Transforming growth factor beta-3 proprotein

Genular Protein ID: 3841236229

Symbol: TGFB3_RAT

Name: Transforming growth factor beta-3 proprotein

UniProtKB Accession Codes:

Q07258 Q56A31

Database IDs:

Citations:

PubMed ID: 7852342

Title: Cloning and expression of glucocorticoid-induced genes in fetal rat lung fibroblasts. Transforming growth factor-beta 3.

PubMed ID: 7852342

DOI: 10.1074/jbc.270.6.2722

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8509457

Title: A role for TGF-beta in oligodendrocyte differentiation.

PubMed ID: 8509457

DOI: 10.1083/jcb.121.6.1397

PubMed ID: 26858265

Title: Plakophilin-2 loss promotes TGF-beta1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes.

PubMed ID: 26858265

DOI: 10.1083/jcb.201507018

Sequence Information:

Length: 412
Mass: 47116
Checksum: 24FD7D899090AA9D
Sequence:

MKMHLQRALV VLALLNLATV SLSLSTCTTL DFGHIKKKRV EAIRGQILSK LRLTSPPEPS 
VMTHVPYQVL ALYNSTRELL EEMHGEREEG CTQETSESEY YAKEIHKFDM IQGLAEHNEL 
AVCPKGITSK VFRFNVSSVE KNGTNLFRAE FRVLRVPNPS SKRTEQRIEL FQILRPDEHI 
AKQRYIGGKN LPTRGTAEWL SFDVTDTVRE WLLRRESNLG LEISIHCPCH TFQPNGDILE 
NVHEVMEIKF KGVDNEDDHG RGDLGRLKKQ KDHHNPHLIL MMIPPHRLDS PGQGGQRKKR 
ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSSDTTHST 
VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tgfb3

Associated with

Other Information

Cloning and expression of glucocorticoid-induced genes in fetal rat lung fibroblasts. Transforming growth factor-beta 3. PubMed ID: 7852342

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A role for TGF-beta in oligodendrocyte differentiation. PubMed ID: 8509457

Plakophilin-2 loss promotes TGF-beta1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes. PubMed ID: 26858265

Database document:

PubMed ID: 7852342

PubMed ID: 15489334

PubMed ID: 8509457

PubMed ID: 26858265