Igf1r | ENSRNOG00000014187 | NCBI 25718

Details for: Igf1r

Gene ID: 25718

Symbol: Igf1r

Ensembl ID: ENSRNOG00000014187

Description: insulin-like growth factor 1 receptor

Associated with

Esr-mediated signaling
(R-RNO-8939211)
Extra-nuclear estrogen signaling
(R-RNO-9009391)
Igf1r signaling cascade
(R-RNO-2428924)
Irs-related events triggered by igf1r
(R-RNO-2428928)
Shc-related events triggered by igf1r
(R-RNO-2428933)
Signaling by nuclear receptors
(R-RNO-9006931)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-RNO-2404192)
Signal transduction
(R-RNO-162582)
Adrenal gland development
(GO:0030325)
Amyloid-beta clearance
(GO:0097242)
Animal organ morphogenesis
(GO:0009887)
Atp binding
(GO:0005524)
Axonogenesis
(GO:0007409)
Brain development
(GO:0007420)
Cardiac atrium development
(GO:0003230)
Cellular response to dexamethasone stimulus
(GO:0071549)
Cellular response to estradiol stimulus
(GO:0071392)
Cellular response to glucose stimulus
(GO:0071333)
Cellular response to insulin stimulus
(GO:0032869)
Cellular response to mechanical stimulus
(GO:0071260)
Cellular response to progesterone stimulus
(GO:0071393)
Cellular response to testosterone stimulus
(GO:0071394)
Cellular response to transforming growth factor beta stimulus
(GO:0071560)
Cellular response to zinc ion starvation
(GO:0034224)
Cellular senescence
(GO:0090398)
Cerebellum development
(GO:0021549)
Dendritic spine maintenance
(GO:0097062)
Epidermis development
(GO:0008544)
Establishment of cell polarity
(GO:0030010)
Estrous cycle
(GO:0044849)
Exocrine pancreas development
(GO:0031017)
G-protein alpha-subunit binding
(GO:0001965)
Hippocampus development
(GO:0021766)
Identical protein binding
(GO:0042802)
Immune response
(GO:0006955)
Insulin-like growth factor binding
(GO:0005520)
Insulin-like growth factor i binding
(GO:0031994)
Insulin-like growth factor receptor activity
(GO:0005010)
Insulin-like growth factor receptor signaling pathway
(GO:0048009)
Insulin binding
(GO:0043559)
Insulin receptor activity
(GO:0005009)
Insulin receptor binding
(GO:0005158)
Insulin receptor signaling pathway
(GO:0008286)
Insulin receptor substrate binding
(GO:0043560)
Male sex determination
(GO:0030238)
Mammary gland development
(GO:0030879)
Mapk cascade
(GO:0000165)
Multicellular organism development
(GO:0007275)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of mapk cascade
(GO:0043409)
Negative regulation of muscle cell apoptotic process
(GO:0010656)
Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051898)
Neuron projection development
(GO:0031175)
Phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0043491)
Phosphatidylinositol 3-kinase binding
(GO:0043548)
Positive regulation of axon regeneration
(GO:0048680)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cold-induced thermogenesis
(GO:0120162)
Positive regulation of cytokinesis
(GO:0032467)
Positive regulation of developmental growth
(GO:0048639)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of dna metabolic process
(GO:0051054)
Positive regulation of kinase activity
(GO:0033674)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of meiotic cell cycle
(GO:0051446)
Positive regulation of mitotic nuclear division
(GO:0045840)
Positive regulation of osteoblast proliferation
(GO:0033690)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of protein-containing complex disassembly
(GO:0043243)
Positive regulation of smooth muscle cell proliferation
(GO:0048661)
Positive regulation of steroid hormone biosynthetic process
(GO:0090031)
Postsynaptic modulation of chemical synaptic transmission
(GO:0099170)
Prostate gland epithelium morphogenesis
(GO:0060740)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein transporter activity
(GO:0140318)
Protein tyrosine kinase activity
(GO:0004713)
Regulation of jnk cascade
(GO:0046328)
Response to alkaloid
(GO:0043279)
Response to ethanol
(GO:0045471)
Response to hormone
(GO:0009725)
Response to insulin
(GO:0032868)
Response to nicotine
(GO:0035094)
Response to nutrient levels
(GO:0031667)
Response to vitamin e
(GO:0033197)
Structural molecule activity
(GO:0005198)
Transcytosis
(GO:0045056)

Other Information

Proteins

Insulin-like growth factor 1 receptor

Genular Protein ID: 2463678662

Symbol: IGF1R_RAT

Name: Insulin-like growth factor 1 receptor

UniProtKB Accession Codes:

P24062

Database IDs:

Citations:

PubMed ID: 7758167

Title: Inhibition of vascular smooth muscle cell growth through antisense transcription of a rat insulin-like growth factor I receptor cDNA.

PubMed ID: 7758167

DOI: 10.1161/01.res.76.6.963

PubMed ID: 2477843

Title: Developmental regulation of the rat insulin-like growth factor I receptor gene.

PubMed ID: 2477843

DOI: 10.1073/pnas.86.19.7451

PubMed ID: 1530648

Title: A new member of the insulin receptor family, insulin receptor-related receptor, is expressed preferentially in the kidney.

PubMed ID: 1530648

DOI: 10.1016/0006-291x(92)91287-z

PubMed ID: 16803852

Title: Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells.

PubMed ID: 16803852

DOI: 10.1152/ajpendo.00565.2005

Sequence Information:

Length: 1370
Mass: 155396
Checksum: A5946897A41CB145
Sequence:

MKSGSGGGSP TSLWGLVFLS AALSLWPTSG EICGPGIDIR NDYQQLKRLE NCTVIEGFLH 
ILLISKAEDY RSYRFPKLTV ITEYLLLFRV AGLESLGDLF PNLTVIRGWK LFYNYALVIF 
EMTNLKDIGL YNLRNITRGA IRIEKNADLC YLSTIDWSLI LDAVSNNYIV GNKPPKECGD 
LCPGTLEEKP MCEKTTINNE YNYRCWTTNR CQKMCPSVCG KRACTENNEC CHPECLGSCH 
TPDDNTTCVA CRHYYYKGVC VPACPPGTYR FEGWRCVDRD FCANIPNAES SDSDGFVIHD 
GECMQECPSG FIRNSTQSMY CIPCEGPCPK VCGDEEKKTK TIDSVTSAQM LQGCTILKGN 
LLINIRRGNN IASELENFMG LIEVVTGYVK IRHSHALVSL SFLKNLRLIL GEEQLEGNYS 
FYVLDNQNLQ QLWDWNHRNL TVRSGKMYFA FNPKLCVSEI YRMEEVTGTK GRQSKGDINT 
RNNGERASCE SDVLRFTSTT TWKNRIIITW HRYRPPDYRD LISFTVYYKE APFKNVTEYD 
GQDACGSNSW NMVDVDLPPN KEGEPGILLH GLKPWTQYAV YVKAVTLTMV ENDHIRGAKS 
EILYIRTNAS VPSIPLDVLS ASNSSSQLIV KWNPPTLPNG NLSYYIVRWQ RQPQDGYLFR 
HNYCSKDKIP IRKYADGTID VEEVTENPKT EVCGGDKGPC CACPKTEAEK QAEKEEAEYR 
KVFENFLHNS IFVPRPERRR RDVLQVANTT MSSRSRNTTV ADTYNITDPE EFETEYPFFE 
SRVDNKERTV ISNLRPFTLY RIDIHSCNHE AEKLGCSASN FVFARTMPAE GADDIPGPVT 
WEPRPENSIF LKWPEPENPN GLILMYEIKY GSQVEDQREC VSRQEYRKYG GAKLNRLNPG 
NYTARIQATS LSGNGSWTDP VFFYVPAKTT YENFMHLIIA LPVAILLIVG GLVIMLYVFH 
RKRNNSRLGN GVLYASVNPE YFSAADVYVP DEWEVAREKI TMNRELGQGS FGMVYEGVAK 
GVVKDEPETR VAIKTVNEAA SMRERIEFLN EASVMKEFNC HHVVRLLGVV SQGQPTLVIM 
ELMTRGDLKS YLRSLRPEVE NNLVLIPPSL SKMIQMAGEI ADGMAYLNAN KFVHRDLAAR 
NCMVAEDFTV KIGDFGMTRD IYETDYYRKG GKGLLPVRWM SPESLKDGVF TTHSDVWSFG 
VVLWEIATLA EQPYQGLSNE QVLRFVMEGG LLDKPDNCPD MLFELMRMCW QYNPKMRPSF 
LEIIGSIKDE MEPSFQEVSF YYSEENKPPE PEELEMELEL EPENMESVPL DPSASSASLP 
LPERHSGHKA ENGPGVLVLR ASFDERQPYA HMNGGRANER ALPLPQSSTC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Igf1r

Associated with

Other Information

Inhibition of vascular smooth muscle cell growth through antisense transcription of a rat insulin-like growth factor I receptor cDNA. PubMed ID: 7758167

Developmental regulation of the rat insulin-like growth factor I receptor gene. PubMed ID: 2477843

A new member of the insulin receptor family, insulin receptor-related receptor, is expressed preferentially in the kidney. PubMed ID: 1530648

Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells. PubMed ID: 16803852

Database document:

PubMed ID: 7758167

PubMed ID: 2477843

PubMed ID: 1530648

PubMed ID: 16803852