Apoe | ENSRNOG00000018454 | NCBI 25728

Details for: Apoe

Gene ID: 25728

Symbol: Apoe

Ensembl ID: ENSRNOG00000018454

Description: apolipoprotein E

Associated with

Binding and uptake of ligands by scavenger receptors
(R-RNO-2173782)
Chylomicron assembly
(R-RNO-8963888)
Chylomicron clearance
(R-RNO-8964026)
Chylomicron remodeling
(R-RNO-8963901)
Hdl remodeling
(R-RNO-8964058)
Metabolism
(R-RNO-1430728)
Metabolism of fat-soluble vitamins
(R-RNO-6806667)
Metabolism of proteins
(R-RNO-392499)
Metabolism of vitamins and cofactors
(R-RNO-196854)
Plasma lipoprotein assembly
(R-RNO-8963898)
Plasma lipoprotein assembly, remodeling, and clearance
(R-RNO-174824)
Plasma lipoprotein clearance
(R-RNO-8964043)
Plasma lipoprotein remodeling
(R-RNO-8963899)
Post-translational protein modification
(R-RNO-597592)
Post-translational protein phosphorylation
(R-RNO-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-RNO-381426)
Retinoid metabolism and transport
(R-RNO-975634)
Scavenging by class a receptors
(R-RNO-3000480)
Sensory perception
(R-RNO-9709957)
Transport of small molecules
(R-RNO-382551)
Vesicle-mediated transport
(R-RNO-5653656)
Visual phototransduction
(R-RNO-2187338)
Amyloid-beta binding
(GO:0001540)
Antioxidant activity
(GO:0016209)
Axon regeneration
(GO:0031103)
Cgmp-mediated signaling
(GO:0019934)
Cholesterol catabolic process
(GO:0006707)
Cholesterol efflux
(GO:0033344)
Cholesterol metabolic process
(GO:0008203)
Cholesterol transfer activity
(GO:0120020)
Chylomicron remnant clearance
(GO:0034382)
Enzyme binding
(GO:0019899)
Gene expression
(GO:0010467)
G protein-coupled receptor signaling pathway
(GO:0007186)
Heparan sulfate proteoglycan binding
(GO:0043395)
Heparin binding
(GO:0008201)
High-density lipoprotein particle assembly
(GO:0034380)
High-density lipoprotein particle clearance
(GO:0034384)
High-density lipoprotein particle remodeling
(GO:0034375)
Hydroxyapatite binding
(GO:0046848)
Identical protein binding
(GO:0042802)
Intracellular calcium ion homeostasis
(GO:0006874)
Lipid binding
(GO:0008289)
Lipid metabolic process
(GO:0006629)
Lipid transport
(GO:0006869)
Lipid transporter activity
(GO:0005319)
Lipid transport involved in lipid storage
(GO:0010877)
Lipoprotein biosynthetic process
(GO:0042158)
Lipoprotein metabolic process
(GO:0042157)
Lipoprotein particle binding
(GO:0071813)
Locomotory exploration behavior
(GO:0035641)
Long-chain fatty acid transport
(GO:0015909)
Long-term memory
(GO:0007616)
Low-density lipoprotein particle receptor binding
(GO:0050750)
Low-density lipoprotein particle remodeling
(GO:0034374)
Melanosome organization
(GO:0032438)
Metal chelating activity
(GO:0046911)
Negative regulation of blood coagulation
(GO:0030195)
Negative regulation of endothelial cell migration
(GO:0010596)
Negative regulation of endothelial cell proliferation
(GO:0001937)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of neuron projection development
(GO:0010977)
Negative regulation of platelet activation
(GO:0010544)
Neuron projection development
(GO:0031175)
Neuron projection regeneration
(GO:0031102)
Nitric oxide mediated signal transduction
(GO:0007263)
Peripheral nervous system axon regeneration
(GO:0014012)
Phosphatidylcholine-sterol o-acyltransferase activator activity
(GO:0060228)
Phospholipid binding
(GO:0005543)
Phospholipid efflux
(GO:0033700)
Positive regulation of cholesterol efflux
(GO:0010875)
Positive regulation of low-density lipoprotein particle receptor catabolic process
(GO:0032805)
Positive regulation of neuron projection development
(GO:0010976)
Protein-containing complex binding
(GO:0044877)
Protein dimerization activity
(GO:0046983)
Protein homodimerization activity
(GO:0042803)
Protein import
(GO:0017038)
Protein localization
(GO:0008104)
Receptor-mediated endocytosis
(GO:0006898)
Regulation of cdc42 protein signal transduction
(GO:0032489)
Regulation of gene expression
(GO:0010468)
Response to dietary excess
(GO:0002021)
Response to insulin
(GO:0032868)
Response to oxidative stress
(GO:0006979)
Response to retinoic acid
(GO:0032526)
Response to tumor necrosis factor
(GO:0034612)
Response to zinc ion
(GO:0010043)
Signaling receptor binding
(GO:0005102)
Tau protein binding
(GO:0048156)
Triglyceride metabolic process
(GO:0006641)
Very-low-density lipoprotein particle clearance
(GO:0034447)
Very-low-density lipoprotein particle receptor binding
(GO:0070326)
Very-low-density lipoprotein particle remodeling
(GO:0034372)
Virion assembly
(GO:0019068)

Other Information

Proteins

Apolipoprotein E

Genular Protein ID: 2122745519

Symbol: APOE_RAT

Name: Apolipoprotein E

UniProtKB Accession Codes:

P02650

Database IDs:

Citations:

PubMed ID: 3797247

Title: Complete nucleotide sequence of the gene encoding the rat apolipoprotein E.

PubMed ID: 3797247

DOI: 10.1093/nar/14.23.9527

PubMed ID: 3020048

Title: Structure and expression of the rat apolipoprotein E gene.

PubMed ID: 3020048

DOI: 10.1016/s0021-9258(18)67087-5

PubMed ID: 6190813

Title: Rat apolipoprotein E mRNA. Cloning and sequencing of double-stranded cDNA.

PubMed ID: 6190813

DOI: 10.1016/s0021-9258(18)32155-0

PubMed ID: 7766086

Title: Secretion by Saccharomyces cerevisiae of rat apolipoprotein E as a fusion to Mucor rennin.

PubMed ID: 7766086

DOI: 10.1007/bf00191183

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 312
Mass: 35753
Checksum: 8180EEE933378D92
Sequence:

MKALWALLLV PLLTGCLAEG ELEVTDQLPG QSDQPWEQAL NRFWDYLRWV QTLSDQVQEE 
LQSSQVTQEL TVLMEDTMTE VKAYKKELEE QLGPVAEETR ARLAKEVQAA QARLGADMED 
LRNRLGQYRN EVNTMLGQST EELRSRLSTH LRKMRKRLMR DADDLQKRLA VYKAGAQEGA 
ERGVSAIRER LGPLVEQGRQ RTANLGAGAA QPLRDRAQAL SDRIRGRLEE VGNQARDRLE 
EVREQMEEVR SKMEEQTQQI RLQAEIFQAR IKGWFEPLVE DMQRQWANLM EKIQASVATN 
SIASTTVPLE NQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Apoe

Associated with

Other Information

Complete nucleotide sequence of the gene encoding the rat apolipoprotein E. PubMed ID: 3797247

Structure and expression of the rat apolipoprotein E gene. PubMed ID: 3020048

Rat apolipoprotein E mRNA. Cloning and sequencing of double-stranded cDNA. PubMed ID: 6190813

Secretion by Saccharomyces cerevisiae of rat apolipoprotein E as a fusion to Mucor rennin. PubMed ID: 7766086

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334