Ppara | ENSRNOG00000021463 | NCBI 25747

Details for: Ppara

Gene ID: 25747

Symbol: Ppara

Ensembl ID: ENSRNOG00000021463

Description: peroxisome proliferator activated receptor alpha

Associated with

Cellular responses to stimuli
(R-RNO-8953897)
Cellular responses to stress
(R-RNO-2262752)
Cellular response to chemical stress
(R-RNO-9711123)
Cytoprotection by hmox1
(R-RNO-9707564)
Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Metabolism of proteins
(R-RNO-392499)
Nuclear receptor transcription pathway
(R-RNO-383280)
Post-translational protein modification
(R-RNO-597592)
Regulation of lipid metabolism by pparalpha
(R-RNO-400206)
Rna polymerase ii transcription
(R-RNO-73857)
Sumo e3 ligases sumoylate target proteins
(R-RNO-3108232)
Sumoylation
(R-RNO-2990846)
Sumoylation of intracellular receptors
(R-RNO-4090294)
Behavioral response to nicotine
(GO:0035095)
Cell differentiation
(GO:0030154)
Cellular response to fructose stimulus
(GO:0071332)
Cellular response to starvation
(GO:0009267)
Circadian regulation of gene expression
(GO:0032922)
Dna-binding transcription activator activity
(GO:0001216)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor binding
(GO:0140297)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Enamel mineralization
(GO:0070166)
Epidermis development
(GO:0008544)
Fatty acid metabolic process
(GO:0006631)
Gluconeogenesis
(GO:0006094)
Heart development
(GO:0007507)
Hormone-mediated signaling pathway
(GO:0009755)
Intracellular receptor signaling pathway
(GO:0030522)
Lipid binding
(GO:0008289)
Lipoprotein metabolic process
(GO:0042157)
Mdm2/mdm4 family protein binding
(GO:0097371)
Mitogen-activated protein kinase kinase kinase binding
(GO:0031435)
Negative regulation of appetite
(GO:0032099)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of cell growth involved in cardiac muscle cell development
(GO:0061052)
Negative regulation of cholesterol storage
(GO:0010887)
Negative regulation of cytokine production involved in inflammatory response
(GO:1900016)
Negative regulation of glycolytic process
(GO:0045820)
Negative regulation of hepatocyte apoptotic process
(GO:1903944)
Negative regulation of inflammatory response
(GO:0050728)
Negative regulation of leukocyte cell-cell adhesion
(GO:1903038)
Negative regulation of macrophage derived foam cell differentiation
(GO:0010745)
Negative regulation of mirna transcription
(GO:1902894)
Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051898)
Negative regulation of reactive oxygen species biosynthetic process
(GO:1903427)
Negative regulation of sequestering of triglyceride
(GO:0010891)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)
Nfat protein binding
(GO:0051525)
Nitric oxide metabolic process
(GO:0046209)
Nuclear receptor activity
(GO:0004879)
Nuclear steroid receptor activity
(GO:0003707)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Phosphatase binding
(GO:0019902)
Positive regulation of atp biosynthetic process
(GO:2001171)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of fatty acid metabolic process
(GO:0045923)
Positive regulation of fatty acid oxidation
(GO:0046321)
Positive regulation of gluconeogenesis
(GO:0045722)
Positive regulation of lipid biosynthetic process
(GO:0046889)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Regulation of cellular ketone metabolic process
(GO:0010565)
Regulation of circadian rhythm
(GO:0042752)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of fatty acid metabolic process
(GO:0019217)
Regulation of gene expression
(GO:0010468)
Regulation of lipid storage
(GO:0010883)
Response to ethanol
(GO:0045471)
Response to hypoxia
(GO:0001666)
Response to insulin
(GO:0032868)
Response to nutrient
(GO:0007584)
Response to organic cyclic compound
(GO:0014070)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Signaling receptor activity
(GO:0038023)
Steroid hormone mediated signaling pathway
(GO:0043401)
Transcription coactivator binding
(GO:0001223)
Ubiquitin conjugating enzyme binding
(GO:0031624)
Wound healing
(GO:0042060)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Peroxisome proliferator-activated receptor alpha

Genular Protein ID: 299200260

Symbol: PPARA_RAT

Name: Peroxisome proliferator-activated receptor alpha

UniProtKB Accession Codes:

P37230

Database IDs:

Citations:

PubMed ID: 1316614

Title: Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor.

PubMed ID: 1316614

DOI: 10.1073/pnas.89.10.4653

PubMed ID: 8828512

Title: The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin.

PubMed ID: 8828512

DOI: 10.1210/endo.137.10.8828512

PubMed ID: 15051727

Title: Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator.

PubMed ID: 15051727

DOI: 10.1074/jbc.m401489200

Sequence Information:

Length: 468
Mass: 52377
Checksum: 2A89E7D715C8DBA9
Sequence:

MVDTESPICP LSPLEADDLE SPLSEEFLQE MGNIQEISQS LGEESSGSFS FADYQYLGSC 
PGSEGSVITD TLSPASSPSS VSCPAVPTST DESPGNALNI ECRICGDKAS GYHYGVHACE 
GCKGFFRRTI RLKLAYDKCD RSCKIQKKNR NKCQYCRFHK CLSVGMSHNA IRFGRMPRSE 
KAKLKAEILT CEHDLKDSET ADLKSLAKRI HEAYLKNFNM NKVKARVILA GKTSNNPPFV 
IHDMETLCMA EKTLVAKMVA NGVENKEAEV RFFHCCQCMS VETVTELTEF AKAIPGFANL 
DLNDQVTLLK YGVYEAIFTM LSSLMNKDGM LIAYGNGFIT REFLKNLRKP FCDIMEPKFD 
FAMKFNALEL DDSDISLFVA AIICCGDRPG LLNIGYIEKL QEGIVHVLKL HLQSNHPDDT 
FLFPKLLQKM VDLRQLVTEH AQLVQVIKKT ESDAALHPLL QEIYRDMY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.