CBY1 | ENSG00000100211 | NCBI 25776

Details for: CBY1

Gene ID: 25776

Symbol: CBY1

Ensembl ID: ENSG00000100211

Description: chibby 1, beta catenin antagonist

Associated with

Deactivation of the beta-catenin transactivating complex
(R-HSA-3769402)
Signaling by wnt
(R-HSA-195721)
Signal transduction
(R-HSA-162582)
Tcf dependent signaling in response to wnt
(R-HSA-201681)
Beta-catenin binding
(GO:0008013)
Canonical wnt signaling pathway
(GO:0060070)
Cardiac muscle cell differentiation
(GO:0055007)
Centriole
(GO:0005814)
Ciliary basal body
(GO:0036064)
Cilium assembly
(GO:0060271)
Cytosol
(GO:0005829)
Fat cell differentiation
(GO:0045444)
Floor plate development
(GO:0033504)
Identical protein binding
(GO:0042802)
Negative regulation of canonical wnt signaling pathway
(GO:0090090)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of wnt signaling pathway
(GO:0030178)
Nuclear speck
(GO:0016607)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein homotetramerization
(GO:0051289)
Protein localization
(GO:0008104)
Trans-golgi network
(GO:0005802)

Other Information

Proteins

Protein chibby homolog 1

Genular Protein ID: 679340472

Symbol: CBY1_HUMAN

Name: Protein chibby homolog 1

UniProtKB Accession Codes:

Q9Y3M2 B2R4S2 Q66GT6 Q9UIK9

Database IDs:

Citations:

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 12529303

Title: Reevaluating human gene annotation: a second-generation analysis of chromosome 22.

PubMed ID: 12529303

DOI: 10.1101/gr.695703

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12712206

Title: Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway.

PubMed ID: 12712206

DOI: 10.1038/nature01570

PubMed ID: 15194699

Title: PIGEA-14, a novel coiled-coil protein affecting the intracellular distribution of polycystin-2.

PubMed ID: 15194699

DOI: 10.1074/jbc.m314206200

PubMed ID: 16424001

Title: TC1 (C8orf4) enhances the Wnt/beta-catenin pathway by relieving antagonistic activity of Chibby.

PubMed ID: 16424001

DOI: 10.1158/0008-5472.can-05-3124

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 27528616

Title: BAR domain-containing FAM92 proteins interact with chibby1 to facilitate ciliogenesis.

PubMed ID: 27528616

DOI: 10.1128/mcb.00160-16

PubMed ID: 30395363

Title: FAM92A underlies nonsyndromic postaxial polydactyly in humans and an abnormal limb and digit skeletal phenotype in mice.

PubMed ID: 30395363

DOI: 10.1002/jbmr.3594

Sequence Information:

Length: 126
Mass: 14470
Checksum: 0D243AD2CC436E55
Sequence:

MPFFGNTFSP KKTPPRKSAS LSNLHSLDRS TREVELGLEY GSPTMNLAGQ SLKFENGQWI 
AETGVSGGVD RREVQRLRRR NQQLEEENNL LRLKVDILLD MLSESTAESH LMEKELDELR 
ISRKRK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CBY1

Associated with

Other Information

Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. PubMed ID: 11230166

Reevaluating human gene annotation: a second-generation analysis of chromosome 22. PubMed ID: 12529303

A genome annotation-driven approach to cloning the human ORFeome. PubMed ID: 15461802

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence of human chromosome 22. PubMed ID: 10591208

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway. PubMed ID: 12712206

PIGEA-14, a novel coiled-coil protein affecting the intracellular distribution of polycystin-2. PubMed ID: 15194699

TC1 (C8orf4) enhances the Wnt/beta-catenin pathway by relieving antagonistic activity of Chibby. PubMed ID: 16424001

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

BAR domain-containing FAM92 proteins interact with chibby1 to facilitate ciliogenesis. PubMed ID: 27528616

FAM92A underlies nonsyndromic postaxial polydactyly in humans and an abnormal limb and digit skeletal phenotype in mice. PubMed ID: 30395363