Details for: QPCT
Associated with
Other Information
Genular Protein ID: 604906942
Symbol: QPCT_HUMAN
Name: Glutaminyl-peptide cyclotransferase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7999256
Title: Molecular cloning, sequence analysis and expression of human pituitary glutaminyl cyclase.
PubMed ID: 7999256
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15063747
Title: Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions.
PubMed ID: 15063747
PubMed ID: 18486145
Title: Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery.
PubMed ID: 18486145
PubMed ID: 16135565
Title: Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation.
PubMed ID: 16135565
PubMed ID: 18072935
Title: A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
PubMed ID: 18072935
DOI: 10.1042/bj20071073
PubMed ID: 21671571
Title: Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center.
PubMed ID: 21671571
DOI: 10.1021/bi200249h
PubMed ID: 21288892
Title: Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding.
PubMed ID: 21288892
Sequence Information:
- Length: 361
- Mass: 40877
- Checksum: 32C26041BCF5ED75
- Sequence:
MAGGRHRRVV GTLHLLLLVA ALPWASRGVS PSASAWPEEK NYHQPAILNS SALRQIAEGT SISEMWQNDL QPLLIERYPG SPGSYAARQH IMQRIQRLQA DWVLEIDTFL SQTPYGYRSF SNIISTLNPT AKRHLVLACH YDSKYFSHWN NRVFVGATDS AVPCAMMLEL ARALDKKLLS LKTVSDSKPD LSLQLIFFDG EEAFLHWSPQ DSLYGSRHLA AKMASTPHPP GARGTSQLHG MDLLVLLDLI GAPNPTFPNF FPNSARWFER LQAIEHELHE LGLLKDHSLE GRYFQNYSYG GVIQDDHIPF LRRGVPVLHL IPSPFPEVWH TMDDNEENLD ESTIDNLNKI LQVFVLEYLH L
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.