VAX2 | ENSG00000116035 | NCBI 25806

Details for: VAX2

Gene ID: 25806

Symbol: VAX2

Ensembl ID: ENSG00000116035

Description: ventral anterior homeobox 2

Associated with

Axonogenesis
(GO:0007409)
Brain development
(GO:0007420)
Central nervous system development
(GO:0007417)
Chromatin
(GO:0000785)
Chromatin dna binding
(GO:0031490)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dorsal/ventral axis specification
(GO:0009950)
Ectoderm development
(GO:0007398)
Embryonic eye morphogenesis
(GO:0048048)
Forebrain development
(GO:0030900)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neuron differentiation
(GO:0030182)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Retina development in camera-type eye
(GO:0060041)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii intronic transcription regulatory region sequence-specific dna binding
(GO:0001162)
Sequence-specific double-stranded dna binding
(GO:1990837)
Visual perception
(GO:0007601)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Ventral anterior homeobox 2

Genular Protein ID: 2910381665

Symbol: VAX2_HUMAN

Name: Ventral anterior homeobox 2

UniProtKB Accession Codes:

Q9UIW0 Q53Y33

Database IDs:

Citations:

PubMed ID: 10485894

Title: A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis.

PubMed ID: 10485894

DOI: 10.1073/pnas.96.19.10729

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22095910

Title: VAX1 mutation associated with microphthalmia, corpus callosum agenesis, and orofacial clefting: The first description of a VAX1 phenotype in humans.

PubMed ID: 22095910

DOI: 10.1002/humu.21658

Sequence Information:

Length: 290
Mass: 30874
Checksum: 917164EE66E66051
Sequence:

MGDGGAERDR GPARRAESGG GGGRCGDRSG AGDLRADGGG HSPTEVAGTS ASSPAGSRES 
GADSDGQPGP GEADHCRRIL VRDAKGTIRE IVLPKGLDLD RPKRTRTSFT AEQLYRLEME 
FQRCQYVVGR ERTELARQLN LSETQVKVWF QNRRTKQKKD QSRDLEKRAS SSASEAFATS 
NILRLLEQGR LLSVPRAPSL LALTPSLPGL PASHRGTSLG DPRNSSPRLN PLSSASASPP 
LPPPLPAVCF SSAPLLDLPA GYELGSSAFE PYSWLERKVG SASSCKKANT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.