NOCT | ENSG00000151014 | NCBI 25819

Details for: NOCT

Gene ID: 25819

Symbol: NOCT

Ensembl ID: ENSG00000151014

Description: nocturnin

Associated with

Bmal1:clock,npas2 activates circadian gene expression
(R-HSA-1368108)
Circadian clock
(R-HSA-400253)
3'-5'-rna exonuclease activity
(GO:0000175)
Circadian regulation of gene expression
(GO:0032922)
Cytoplasm
(GO:0005737)
Deadenylation-dependent decapping of nuclear-transcribed mrna
(GO:0000290)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Mrna binding
(GO:0003729)
Mrna stabilization
(GO:0048255)
Nadph phosphatase activity
(GO:0102757)
Nadp metabolic process
(GO:0006739)
Nadp phosphatase activity
(GO:0019178)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of osteoblast differentiation
(GO:0045668)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
P-body
(GO:0000932)
P-body assembly
(GO:0033962)
Perinuclear region of cytoplasm
(GO:0048471)
Poly(a)-specific ribonuclease activity
(GO:0004535)
Positive regulation of fat cell differentiation
(GO:0045600)
Regulation of circadian rhythm
(GO:0042752)
Regulation of embryonic development
(GO:0045995)
Response to extracellular stimulus
(GO:0009991)
Response to lipopolysaccharide
(GO:0032496)
Transcription by rna polymerase ii
(GO:0006366)

Other Information

Proteins

Carbon catabolite repression 4-like protein

Genular Protein ID: 3924791564

Symbol: NOCT_HUMAN

Name: Carbon catabolite repression 4-like protein

UniProtKB Accession Codes:

Q9UK39 D3DNY5 Q14D51 Q9HD93 Q9HD94 Q9HD95

Database IDs:

Citations:

PubMed ID: 10521507

Title: Characterization of a mammalian gene related to the yeast CCR4 general transcription factor and revealed by transposon insertion.

PubMed ID: 10521507

DOI: 10.1074/jbc.274.43.31068

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22331129

Title: The role of nocturnin in early adipogenesis and modulation of systemic insulin resistance in human.

PubMed ID: 22331129

DOI: 10.1038/oby.2012.37

PubMed ID: 22608110

Title: Nocturnin: at the crossroads of clocks and metabolism.

PubMed ID: 22608110

DOI: 10.1016/j.tem.2012.03.007

PubMed ID: 29860338

Title: The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells.

PubMed ID: 29860338

DOI: 10.1093/nar/gky412

PubMed ID: 30389976

Title: Crystal Structure of Human Nocturnin Catalytic Domain.

PubMed ID: 30389976

DOI: 10.1038/s41598-018-34615-0

PubMed ID: 31147539

Title: The metabolites NADP+ and NADPH are the targets of the circadian protein Nocturnin (Curled).

PubMed ID: 31147539

DOI: 10.1038/s41467-019-10125-z

Sequence Information:

Length: 431
Mass: 48196
Checksum: 5BDEFC43173B2D0C
Sequence:

MFHSPRRLCS ALLQRDAPGL RRLPAPGLRR PLSPPAAVPR PASPRLLAAA SAASGAARSC 
SRTVCSMGTG TSRLYSALAK TLNSSAASQH PEYLVSPDPE HLEPIDPKEL LEECRAVLHT 
RPPRFQRDFV DLRTDCPSTH PPIRVMQWNI LAQALGEGKD NFVQCPVEAL KWEERKCLIL 
EEILAYQPDI LCLQEVDHYF DTFQPLLSRL GYQGTFFPKP WSPCLDVEHN NGPDGCALFF 
LQNRFKLVNS ANIRLTAMTL KTNQVAIAQT LECKESGRQF CIAVTHLKAR TGWERFRSAQ 
GCDLLQNLQN ITQGAKIPLI VCGDFNAEPT EEVYKHFASS SLNLNSAYKL LSADGQSEPP 
YTTWKIRTSG ECRHTLDYIW YSKHALNVRS ALDLLTEEQI GPNRLPSFNY PSDHLSLVCD 
FSFTEESDGL S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NOCT

Associated with

Other Information

Characterization of a mammalian gene related to the yeast CCR4 general transcription factor and revealed by transposon insertion. PubMed ID: 10521507

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The role of nocturnin in early adipogenesis and modulation of systemic insulin resistance in human. PubMed ID: 22331129

Nocturnin: at the crossroads of clocks and metabolism. PubMed ID: 22608110

The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells. PubMed ID: 29860338

Crystal Structure of Human Nocturnin Catalytic Domain. PubMed ID: 30389976

The metabolites NADP+ and NADPH are the targets of the circadian protein Nocturnin (Curled). PubMed ID: 31147539