Details for: PRDX5

Gene ID: 25824

Symbol: PRDX5

Ensembl ID: ENSG00000126432

Description: peroxiredoxin 5

Associated with

Other Information

Genular Protein ID: 3011450595

Symbol: PRDX5_HUMAN

Name: Peroxiredoxin-5, mitochondrial

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10095767

Title: A novel human DNA-binding protein with sequence similarity to a subfamily of redox proteins which is able to repress RNA-polymerase-III-driven transcription of the Alu-family retroposons in vitro.

PubMed ID: 10095767

DOI: 10.1046/j.1432-1327.1999.00162.x

PubMed ID: 10514471

Title: Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro.

PubMed ID: 10514471

DOI: 10.1074/jbc.274.42.29897

PubMed ID: 10521424

Title: Cloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin family.

PubMed ID: 10521424

DOI: 10.1074/jbc.274.43.30451

PubMed ID: 10679306

Title: Mouse peroxiredoxin V is a thioredoxin peroxidase that inhibits p53-induced apoptosis.

PubMed ID: 10679306

DOI: 10.1006/bbrc.2000.2231

PubMed ID: 10751410

Title: Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate.

PubMed ID: 10751410

DOI: 10.1074/jbc.m001943200

PubMed ID: 10931946

Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.

PubMed ID: 10931946

DOI: 10.1073/pnas.160270997

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1286669

Title: Human liver protein map: a reference database established by microsequencing and gel comparison.

PubMed ID: 1286669

DOI: 10.1002/elps.11501301201

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 11518528

Title: Crystal structure of human peroxiredoxin 5, a novel type of mammalian peroxiredoxin at 1.5-A resolution.

PubMed ID: 11518528

DOI: 10.1006/jmbi.2001.4853

PubMed ID: 18489898

Title: The crystal structures of oxidized forms of human peroxiredoxin 5 with an intramolecular disulfide bond confirm the proposed enzymatic mechanism for atypical 2-Cys peroxiredoxins.

PubMed ID: 18489898

DOI: 10.1016/j.abb.2008.04.036

PubMed ID: 20643143

Title: Structural evidence that peroxiredoxin catalytic power is based on transition-state stabilization.

PubMed ID: 20643143

DOI: 10.1016/j.jmb.2010.07.022

PubMed ID: 31740833

Title: ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5.

PubMed ID: 31740833

DOI: 10.1038/s41589-019-0399-y

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 214
  • Mass: 22086
  • Checksum: DA1DEB21120254EE
  • Sequence:
  • MGLAGVCALR RSAGYILVGG AGGQSAAAAA RRYSEGEWAS GGVRSFSRAA AAMAPIKVGD 
    AIPAVEVFEG EPGNKVNLAE LFKGKKGVLF GVPGAFTPGC SKTHLPGFVE QAEALKAKGV 
    QVVACLSVND AFVTGEWGRA HKAEGKVRLL ADPTGAFGKE TDLLLDDSLV SIFGNRRLKR 
    FSMVVQDGIV KALNVEPDGT GLTCSLAPNI ISQL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.