SUMF2 | ENSG00000129103 | NCBI 25870

Details for: SUMF2

Gene ID: 25870

Symbol: SUMF2

Ensembl ID: ENSG00000129103

Description: sulfatase modifying factor 2

Associated with

Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
(R-HSA-163841)
Glycosphingolipid catabolism
(R-HSA-9840310)
Glycosphingolipid metabolism
(R-HSA-1660662)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Sphingolipid metabolism
(R-HSA-428157)
The activation of arylsulfatases
(R-HSA-1663150)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum lumen
(GO:0005788)
Identical protein binding
(GO:0042802)
Metal ion binding
(GO:0046872)
Protein binding
(GO:0005515)

Other Information

Proteins

SUMF2_HUMAN

Genular Protein ID: 3991134424

Symbol: SUMF2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8NBJ7 B4DU41 B4DWQ0 Q14DW5 Q53ZE3 Q96BH2 Q9BRN3 Q9BWI1 Q9Y405

Database IDs:

Citations:

PubMed ID: 12757706

Title: The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases.

PubMed ID: 12757706

DOI: 10.1016/s0092-8674(03)00348-9

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15708861

Title: Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme.

PubMed ID: 15708861

DOI: 10.1074/jbc.m413698200

PubMed ID: 15962010

Title: Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2.

PubMed ID: 15962010

DOI: 10.1038/sj.embor.7400454

PubMed ID: 18266766

Title: Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals.

PubMed ID: 18266766

DOI: 10.1111/j.1742-4658.2008.06271.x

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 15687489

Title: Crystal structure of human pFGE, the paralog of the Calpha-formylglycine-generating enzyme.

PubMed ID: 15687489

DOI: 10.1074/jbc.m414317200

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28397838

Title: Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.

PubMed ID: 28397838

DOI: 10.1038/mp.2017.60

Sequence Information:

Length: 301
Mass: 33843
Checksum: 1E834CEA56922755
Sequence:

MARHGLPLLP LLSLLVGAWL KLGNGQATSM VQLQGGRFLM GTNSPDSRDG DGPVREATVK 
PFAIDIFPVT NKDFRDFVRE KKYRTEAEMF GWSFVFEDFV SDELRNKATQ PMKSVLWWLP 
VEKAFWRQPA GPGSGIRERL EHPVLHVSWN DARAYCAWRG KRLPTEEEWE FAARGGLKGQ 
VYPWGNWFQP NRTNLWQGKF PKGDKAEDGF HGVSPVNAFP AQNNYGLYDL LGNVWEWTAS 
PYQAAEQDMR VLRGASWIDT ADGSANHRAR VTTRMGNTPD SASDNLGFRC AADAGRPPGE 
L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SUMF2

Associated with

Other Information

The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. PubMed ID: 12757706

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. PubMed ID: 16303743

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

The DNA sequence of human chromosome 7. PubMed ID: 12853948

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme. PubMed ID: 15708861

Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2. PubMed ID: 15962010

Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals. PubMed ID: 18266766

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Crystal structure of human pFGE, the paralog of the Calpha-formylglycine-generating enzyme. PubMed ID: 15687489

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families. PubMed ID: 28397838