MPC2 | ENSG00000143158 | NCBI 25874

Details for: MPC2

Gene ID: 25874

Symbol: MPC2

Ensembl ID: ENSG00000143158

Description: mitochondrial pyruvate carrier 2

Associated with

Metabolism
(R-HSA-1430728)
Pyruvate metabolism
(R-HSA-70268)
Pyruvate metabolism and citric acid (tca) cycle
(R-HSA-71406)
The citric acid (tca) cycle and respiratory electron transport
(R-HSA-1428517)
Acetyl-coa biosynthetic process from pyruvate
(GO:0006086)
Identical protein binding
(GO:0042802)
Inner mitochondrial membrane protein complex
(GO:0098800)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial pyruvate transmembrane transport
(GO:0006850)
Mitochondrion
(GO:0005739)
Nucleus
(GO:0005634)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus
(GO:0035774)
Protein binding
(GO:0005515)
Pyruvate transmembrane transporter activity
(GO:0050833)

Other Information

Proteins

Mitochondrial pyruvate carrier 2

Genular Protein ID: 3110611433

Symbol: MPC2_HUMAN

Name: Mitochondrial pyruvate carrier 2

UniProtKB Accession Codes:

O95563 A8K261 Q3SXR6 Q6FIF3

Database IDs:

Citations:

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22628558

Title: A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.

PubMed ID: 22628558

DOI: 10.1126/science.1218099

PubMed ID: 26253029

Title: Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect.

PubMed ID: 26253029

DOI: 10.1016/j.molcel.2015.06.035

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27317664

Title: MPC1-like Is a Placental Mammal-specific Mitochondrial Pyruvate Carrier Subunit Expressed in Postmeiotic Male Germ Cells.

PubMed ID: 27317664

DOI: 10.1074/jbc.m116.733840

PubMed ID: 29472561

Title: Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter.

PubMed ID: 29472561

DOI: 10.1038/s41598-018-21740-z

PubMed ID: 32403431

Title: Characteristic Analysis of Homo- and Heterodimeric Complexes of Human Mitochondrial Pyruvate Carrier Related to Metabolic Diseases.

PubMed ID: 32403431

DOI: 10.3390/ijms21093403

Sequence Information:

Length: 127
Mass: 14279
Checksum: D82E5879AB2EEA68
Sequence:

MSAAGARGLR ATYHRLLDKV ELMLPEKLRP LYNHPAGPRT VFFWAPIMKW GLVCAGLADM 
ARPAEKLSTA QSAVLMATGF IWSRYSLVII PKNWSLFAVN FFVGAAGASQ LFRIWRYNQE 
LKAKAHK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: MPC2

Associated with

Other Information

Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. PubMed ID: 11230166

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Initial characterization of the human central proteome. PubMed ID: 21269460

A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. PubMed ID: 22628558

Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect. PubMed ID: 26253029

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

MPC1-like Is a Placental Mammal-specific Mitochondrial Pyruvate Carrier Subunit Expressed in Postmeiotic Male Germ Cells. PubMed ID: 27317664

Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter. PubMed ID: 29472561

Characteristic Analysis of Homo- and Heterodimeric Complexes of Human Mitochondrial Pyruvate Carrier Related to Metabolic Diseases. PubMed ID: 32403431