Details for: POC1A

Gene ID: 25886

Symbol: POC1A

Ensembl ID: ENSG00000164087

Description: POC1 centriolar protein A

Associated with

Other Information

Genular Protein ID: 1604017427

Symbol: POC1A_HUMAN

Name: POC1 centriolar protein homolog A

UniProtKB Accession Codes:

Q8NBT0 A4FUW4 E9PFC6 Q0VDF8 Q2TAK6 Q96IK6 Q9UFJ8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EPD 1 Ensembl 3 GO 6 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 RefSeq 3 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 18068700

Title: Pix1 and Pix2 are novel WD40 microtubule-associated proteins that colocalize with mitochondria in Xenopus germ plasm and centrosomes in human cells.

PubMed ID: 18068700

DOI: 10.1016/j.yexcr.2007.10.019

PubMed ID: 20008567

Title: Basal body stability and ciliogenesis requires the conserved component Poc1.

PubMed ID: 20008567

DOI: 10.1083/jcb.200908019

PubMed ID: 19109428

Title: Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control.

PubMed ID: 19109428

DOI: 10.1091/mbc.e08-06-0619

PubMed ID: 22840364

Title: POC1A truncation mutation causes a ciliopathy in humans characterized by primordial dwarfism.

PubMed ID: 22840364

DOI: 10.1016/j.ajhg.2012.05.025

PubMed ID: 23015594

Title: Poc1A and Poc1B act together in human cells to ensure centriole integrity.

PubMed ID: 23015594

DOI: 10.1242/jcs.111203

PubMed ID: 22840363

Title: Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis syndrome is caused by a POC1A mutation.

PubMed ID: 22840363

DOI: 10.1016/j.ajhg.2012.06.003

Sequence Information:

  • Length: 407
  • Mass: 45009
  • Checksum: A5BF28F024DCCC98
  • Sequence:
    • MAAPCAEDPS LERHFKGHRD AVTCVDFSIN TKQLASGSMD SCLMVWHMKP QSRAYRFTGH 
KDAVTCVNFS PSGHLLASGS RDKTVRIWVP NVKGESTVFR AHTATVRSVH FCSDGQSFVT 
ASDDKTVKVW ATHRQKFLFS LSQHINWVRC AKFSPDGRLI VSASDDKTVK LWDKSSRECV 
HSYCEHGGFV TYVDFHPSGT CIAAAGMDNT VKVWDVRTHR LLQHYQLHSA AVNGLSFHPS 
GNYLITASSD STLKILDLME GRLLYTLHGH QGPATTVAFS RTGEYFASGG SDEQVMVWKS 
NFDIVDHGEV TKVPRPPATL ASSMGNLPEV DFPVPPGRGR SVESVQSQPQ EPVSVPQTLT 
STLEHIVGQL DVLTQTVSIL EQRLTLTEDK LKQCLENQQL IMQRATP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.