RNF19A | ENSG00000034677 | NCBI 25897

Details for: RNF19A

Gene ID: 25897

Symbol: RNF19A

Ensembl ID: ENSG00000034677

Description: ring finger protein 19A, RBR E3 ubiquitin protein ligase

Associated with

Adaptive immune system
(R-HSA-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-HSA-983168)
Class i mhc mediated antigen processing & presentation
(R-HSA-983169)
Immune system
(R-HSA-168256)
Centrosome
(GO:0005813)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Glutamatergic synapse
(GO:0098978)
Hippocampal mossy fiber to ca3 synapse
(GO:0098686)
Membrane
(GO:0016020)
Microtubule cytoskeleton organization
(GO:0000226)
Postsynapse
(GO:0098794)
Protein binding
(GO:0005515)
Protein polyubiquitination
(GO:0000209)
Regulation of protein catabolic process at postsynapse, modulating synaptic transmission
(GO:0099576)
Ubiquitin-dependent protein catabolic process
(GO:0006511)
Ubiquitin conjugating enzyme binding
(GO:0031624)
Ubiquitin ligase complex
(GO:0000151)
Ubiquitin protein ligase activity
(GO:0061630)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

E3 ubiquitin-protein ligase RNF19A

Genular Protein ID: 3173227645

Symbol: RN19A_HUMAN

Name: E3 ubiquitin-protein ligase RNF19A

UniProtKB Accession Codes:

Q9NV58 A3KCU9 Q52LG1 Q9H5H9 Q9H8M8 Q9UFG0 Q9UFX6 Q9Y4Y1

Database IDs:

Citations:

PubMed ID: 11237715

Title: A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity.

PubMed ID: 11237715

DOI: 10.1006/bbrc.2001.4414

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10976766

Title: A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

PubMed ID: 10976766

DOI: 10.1023/a:1007177623283

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12145308

Title: Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity.

PubMed ID: 12145308

DOI: 10.1074/jbc.m206559200

PubMed ID: 12750386

Title: Dorfin localizes to Lewy bodies and ubiquitylates synphilin-1.

PubMed ID: 12750386

DOI: 10.1074/jbc.m302763200

PubMed ID: 15456787

Title: Physical and functional interaction between dorfin and valosin-containing protein that are colocalized in ubiquitylated inclusions in neurodegenerative disorders.

PubMed ID: 15456787

DOI: 10.1074/jbc.m406683200

PubMed ID: 16513638

Title: Calcium-sensing receptor ubiquitination and degradation mediated by the E3 ubiquitin ligase dorfin.

PubMed ID: 16513638

DOI: 10.1074/jbc.m513552200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

Length: 838
Mass: 90696
Checksum: 00A7DED5023FDC06
Sequence:

MQEQEIGFIS KYNEGLCVNT DPVSILTSIL DMSLHRQMGS DRDLQSSASS VSLPSVKKAP 
KKRRISIGSL FRRKKDNKRK SRELNGGVDG IASIESIHSE MCTDKNSIFS TNTSSDNGLT 
SISKQIGDFI ECPLCLLRHS KDRFPDIMTC HHRSCVDCLR QYLRIEISES RVNISCPECT 
ERFNPHDIRL ILSDDVLMEK YEEFMLRRWL VADPDCRWCP APDCGYAVIA FGCASCPKLT 
CGREGCGTEF CYHCKQIWHP NQTCDAARQE RAQSLRLRTI RSSSISYSQE SGAAADDIKP 
CPRCAAYIIK MNDGSCNHMT CAVCGCEFCW LCMKEISDLH YLSPSGCTFW GKKPWSRKKK 
ILWQLGTLVG APVGIALIAG IAIPAMIIGI PVYVGRKIHN RYEGKDVSKH KRNLAIAGGV 
TLSVIVSPVV AAVTVGIGVP IMLAYVYGVV PISLCRSGGC GVSAGNGKGV RIEFDDENDI 
NVGGTNTAVD TTSVAEARHN PSIGEGSVGG LTGSLSASGS HMDRIGAIRD NLSETASTMA 
LAGASITGSL SGSAMVNCFN RLEVQADVQK ERYSLSGESG TVSLGTVSDN ASTKAMAGSI 
LNSYIPLDKE GNSMEVQVDI ESKPSKFRHN SGSSSVDDGS ATRSHAGGSS SGLPEGKSSA 
TKWSKEATAG KKSKSGKLRK KGNMKINETR EDMDAQLLEQ QSTNSSEFEA PSLSDSMPSV 
ADSHSSHFSE FSCSDLESMK TSCSHGSSDY HTRFATVNIL PEVENDRLEN SPHQCSISVV 
TQTASCSEVS QLNHIAEEHG NNGIKPNVDL YFGDALKETN NNHSHQTMEL KVAIQTEI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RNF19A

Associated with

Other Information

A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity. PubMed ID: 11237715

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening. PubMed ID: 10976766

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity. PubMed ID: 12145308

Dorfin localizes to Lewy bodies and ubiquitylates synphilin-1. PubMed ID: 12750386

Physical and functional interaction between dorfin and valosin-containing protein that are colocalized in ubiquitylated inclusions in neurodegenerative disorders. PubMed ID: 15456787

Calcium-sensing receptor ubiquitination and degradation mediated by the E3 ubiquitin ligase dorfin. PubMed ID: 16513638

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569