CNOT10 | ENSG00000182973 | NCBI 25904

Details for: CNOT10

Gene ID: 25904

Symbol: CNOT10

Ensembl ID: ENSG00000182973

Description: CCR4-NOT transcription complex subunit 10

Associated with

Deadenylation-dependent mrna decay
(R-HSA-429914)
Deadenylation of mrna
(R-HSA-429947)
Developmental biology
(R-HSA-1266738)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
M-decay: degradation of maternal mrnas by maternally stored factors
(R-HSA-9820841)
Maternal to zygotic transition (mzt)
(R-HSA-9816359)
Metabolism of rna
(R-HSA-8953854)
Rna polymerase ii transcription
(R-HSA-73857)
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
(R-HSA-6804115)
Tp53 regulates transcription of cell cycle genes
(R-HSA-6791312)
Transcriptional regulation by tp53
(R-HSA-3700989)
Ccr4-not complex
(GO:0030014)
Cytosol
(GO:0005829)
Membrane
(GO:0016020)
Mrna catabolic process
(GO:0006402)
Negative regulation of translation
(GO:0017148)
Nuclear-transcribed mrna poly(a) tail shortening
(GO:0000289)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Regulatory ncrna-mediated gene silencing
(GO:0031047)

Other Information

Proteins

CCR4-NOT transcription complex subunit 10

Genular Protein ID: 3060777072

Symbol: CNO10_HUMAN

Name: CCR4-NOT transcription complex subunit 10

UniProtKB Accession Codes:

Q9H9A5 B7Z7L1 F8WAF2 Q9BU30 Q9H5J7 Q9H8X1 Q9H9W0 Q9HAH3 Q9UFJ2

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19558367

Title: Human Ccr4-Not complexes contain variable deadenylase subunits.

PubMed ID: 19558367

DOI: 10.1042/bj20090500

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23232451

Title: C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex.

PubMed ID: 23232451

DOI: 10.4161/rna.23065

PubMed ID: 23221646

Title: Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs.

PubMed ID: 23221646

DOI: 10.1093/nar/gks1133

PubMed ID: 23303381

Title: NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain.

PubMed ID: 23303381

DOI: 10.4161/rna.23018

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

Length: 744
Mass: 82310
Checksum: BA1984B71F0A1E7A
Sequence:

MAADKPADQG AEKHEGTGQS SGITDQEKEL STNAFQAFTS GNYDACLQHL ACLQDINKDD 
YKIILNTAVA EFFKSNQTTT DNLRQTLNQL KNQVHSAVEE MDGLDDVENS MLYYNQAVIL 
YHLRQYTEAI SVGEKLYQFI EPFEEKFAQA VCFLLVDLYI LTYQAEKALH LLAVLEKMIS 
QGNNNKNGKN ETGNNNNKDG SNHKAESGAL IEAAKSKIHQ YKVRAYIQMK SLKACKREIK 
SVMNTAGNSA PSLFLKSNFE YLRGNYRKAV KLLNSSNIAE HPGFMKTGEC LRCMFWNNLG 
CIHFAMSKHN LGIFYFKKAL QENDNVCAQL SAGSTDPGKK FSGRPMCTLL TNKRYELLYN 
CGIQLLHIGR PLAAFECLIE AVQVYHANPR LWLRLAECCI AANKGTSEQE TKGLPSKKGI 
VQSIVGQGYH RKIVLASQSI QNTVYNDGQS SAIPVASMEF AAICLRNALL LLPEEQQDPK 
QENGAKNSNQ LGGNTESSES SETCSSKSHD GDKFIPAPPS SPLRKQELEN LKCSILACSA 
YVALALGDNL MALNHADKLL QQPKLSGSLK FLGHLYAAEA LISLDRISDA ITHLNPENVT 
DVSLGISSNE QDQGSDKGEN EAMESSGKRA PQCYPSSVNS ARTVMLFNLG SAYCLRSEYD 
KARKCLHQAA SMIHPKEVPP EAILLAVYLE LQNGNTQLAL QIIKRNQLLP AVKTHSEVRK 
KPVFQPVHPI QPIQMPAFTT VQRK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CNOT10

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence, annotation and analysis of human chromosome 3. PubMed ID: 16641997

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Human Ccr4-Not complexes contain variable deadenylase subunits. PubMed ID: 19558367

Initial characterization of the human central proteome. PubMed ID: 21269460

C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex. PubMed ID: 23232451

Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs. PubMed ID: 23221646

NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain. PubMed ID: 23303381

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569