Details for: CLIC4

Gene ID: 25932

Symbol: CLIC4

Ensembl ID: ENSG00000169504

Description: chloride intracellular channel 4

Associated with

Other Information

Genular Protein ID: 4153367490

Symbol: CLIC4_HUMAN

Name: Chloride intracellular channel protein 4

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10070163

Title: A novel p64-related Cl- channel: subcellular distribution and nephron segment-specific expression.

PubMed ID: 10070163

DOI: 10.1152/ajprenal.1999.276.3.f398

PubMed ID: 10191309

Title: A 29 kDa intracellular chloride channel p64H1 is associated with large dense-core vesicles in rat hippocampal neurons.

PubMed ID: 10191309

DOI: 10.1523/jneurosci.19-08-02919.1999

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10793131

Title: Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli.

PubMed ID: 10793131

DOI: 10.1091/mbc.11.5.1509

PubMed ID: 12163372

Title: Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-beta1-mediated conversion of fibroblasts to myofibroblasts.

PubMed ID: 12163372

DOI: 10.1016/s0002-9440(10)64203-4

PubMed ID: 12163479

Title: AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member.

PubMed ID: 12163479

DOI: 10.1074/jbc.m112277200

PubMed ID: 14569596

Title: CLIC4 is enriched at cell-cell junctions and colocalizes with AKAP350 at the centrosome and midbody of cultured mammalian cells.

PubMed ID: 14569596

DOI: 10.1002/cm.10141

PubMed ID: 16239224

Title: Proteomic analysis of vascular endothelial growth factor-induced endothelial cell differentiation reveals a role for chloride intracellular channel 4 (CLIC4) in tubular morphogenesis.

PubMed ID: 16239224

DOI: 10.1074/jbc.m506724200

PubMed ID: 17200346

Title: Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancers.

PubMed ID: 17200346

DOI: 10.1158/1078-0432.ccr-06-1562

PubMed ID: 17636002

Title: CLIC4 mediates and is required for Ca2+-induced keratinocyte differentiation.

PubMed ID: 17636002

DOI: 10.1242/jcs.002741

PubMed ID: 18302930

Title: CLIC4 interacts with histamine H3 receptor and enhances the receptor cell surface expression.

PubMed ID: 18302930

DOI: 10.1016/j.bbrc.2008.02.071

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19247789

Title: Chloride intracellular channel 4 is involved in endothelial proliferation and morphogenesis in vitro.

PubMed ID: 19247789

DOI: 10.1007/s10456-009-9139-3

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 16176272

Title: Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4.

PubMed ID: 16176272

DOI: 10.1111/j.1742-4658.2005.04909.x

PubMed ID: 16581025

Title: Trimeric structure of the wild soluble chloride intracellular ion channel CLIC4 observed in crystals.

PubMed ID: 16581025

DOI: 10.1016/j.bbrc.2006.03.099

Sequence Information:

  • Length: 253
  • Mass: 28772
  • Checksum: 3DD21A33C66626A5
  • Sequence:
  • MALSMPLNGL KEEDKEPLIE LFVKAGSDGE SIGNCPFSQR LFMILWLKGV VFSVTTVDLK 
    RKPADLQNLA PGTHPPFITF NSEVKTDVNK IEEFLEEVLC PPKYLKLSPK HPESNTAGMD 
    IFAKFSAYIK NSRPEANEAL ERGLLKTLQK LDEYLNSPLP DEIDENSMED IKFSTRKFLD 
    GNEMTLADCN LLPKLHIVKV VAKKYRNFDI PKEMTGIWRY LTNAYSRDEF TNTCPSDKEV 
    EIAYSDVAKR LTK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.