Details for: SH2B1

Gene ID: 25970

Symbol: SH2B1

Ensembl ID: ENSG00000178188

Description: SH2B adaptor protein 1

Associated with

Other Information

Genular Protein ID: 3488645435

Symbol: SH2B1_HUMAN

Name: SH2B adapter protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15767667

Title: Kinase activation through dimerization by human SH2-B.

PubMed ID: 15767667

DOI: 10.1128/mcb.25.7.2607-2621.2005

PubMed ID: 10718198

Title: Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10718198

DOI: 10.1093/dnares/7.1.65

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9498552

Title: PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor.

PubMed ID: 9498552

DOI: 10.1093/oxfordjournals.jbchem.a021868

PubMed ID: 9742218

Title: SH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase.

PubMed ID: 9742218

DOI: 10.1042/bj3350103

PubMed ID: 9694882

Title: Platelet-derived growth factor (PDGF) stimulates the association of SH2-Bbeta with PDGF receptor and phosphorylation of SH2-Bbeta.

PubMed ID: 9694882

DOI: 10.1074/jbc.273.33.21239

PubMed ID: 10594240

Title: Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain.

PubMed ID: 10594240

DOI: 10.1007/s003359901183

PubMed ID: 11751854

Title: SH2-B family members differentially regulate JAK family tyrosine kinases.

PubMed ID: 11751854

DOI: 10.1074/jbc.m109165200

PubMed ID: 11827956

Title: Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation.

PubMed ID: 11827956

DOI: 10.1074/jbc.m102777200

PubMed ID: 14565960

Title: SH2-B is a positive regulator of nerve growth factor-mediated activation of the Akt/Forkhead pathway in PC12 cells.

PubMed ID: 14565960

DOI: 10.1074/jbc.m310040200

PubMed ID: 16569669

Title: Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowth.

PubMed ID: 16569669

DOI: 10.1242/jcs.02845

PubMed ID: 17471236

Title: SH2B1beta adaptor is a key enhancer of RET tyrosine kinase signaling.

PubMed ID: 17471236

DOI: 10.1038/sj.onc.1210480

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

  • Length: 756
  • Mass: 79366
  • Checksum: CF680B57114CB1D3
  • Sequence:
  • MNGAPSPEDG ASPSSPPLPP PPPPSWREFC ESHARAAALD FARRFRLYLA SHPQYAGPGA 
    EAAFSRRFAE LFLQHFEAEV ARASGSLSPP ILAPLSPGAE ISPHDLSLES CRVGGPLAVL 
    GPSRSSEDLA GPLPSSVSSS STTSSKPKLK KRFSLRSVGR SVRGSVRGIL QWRGTVDPPS 
    SAGPLETSSG PPVLGGNSNS NSSGGAGTVG RGLVSDGTSP GERWTHRFER LRLSRGGGAL 
    KDGAGMVQRE ELLSFMGAEE AAPDPAGVGR GGGVAGPPSG GGGQPQWQKC RLLLRSEGEG 
    GGGSRLEFFV PPKASRPRLS IPCSSITDVR TTTALEMPDR ENTFVVKVEG PSEYIMETVD 
    AQHVKAWVSD IQECLSPGPC PATSPRPMTL PLAPGTSFLT RENTDSLELS CLNHSESLPS 
    QDLLLGPSES NDRLSQGAYG GLSDRPSASI SPSSASIAAS HFDSMELLPP ELPPRIPIEE 
    GPPTGTVHPL SAPYPPLDTP ETATGSFLFQ GEPEGGEGDQ PLSGYPWFHG MLSRLKAAQL 
    VLTGGTGSHG VFLVRQSETR RGEYVLTFNF QGKAKHLRLS LNEEGQCRVQ HLWFQSIFDM 
    LEHFRVHPIP LESGGSSDVV LVSYVPSSQR QQEPTTSHDP PQPPEPPSWT DPPQPGAEEA 
    SRAPEVAAAA AAAAKERQEK EKAGGGGVPE ELVPVVELVP VVELEEAIAP GSEAQGAGSG 
    GDAGVPPMVQ LQQSPLGGDG EEGGHPRAIN NQYSFV

Genular Protein ID: 1538695030

Symbol: B3KNV5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 756
  • Mass: 79336
  • Checksum: C9DF602A73AA92D3
  • Sequence:
  • MNGAPSPEDG ASPSSPPLPP PPPPSWREFC ESHARAAALD FARRFRLYLA SHPQYAGPGA 
    EAAFSRRFAE LFLQHFEAEV ARASGSLSPP ILAPLSPGAE ISPHDLSLES CRVGGPLAVL 
    GPSRSSEDLA GPLPSSVSSS STTSSKPKLK KRFSLRSVGR SVRGSVRGIL QWRGTVDPPS 
    SAGPLETSSG PPVLGGNSNS NSSGGAGTVG RGLVSDGTSP GERWTHRFER LRLSRGGGAL 
    KDGAGMVQRE ELLSFMGAEE AAPDPAGVGR GGGVAGPPSG GGGQPQWQKC RLLLRSEGEG 
    GGGSRLEFFV PPKASRPRLS IPCSSITDVR TTTALEMPDR ENTFVVKVEG PSEYIMETVD 
    AQHVKAWVSD IQECLSPGPC PATSPRPMTL PLAPGTSFLT RENTDSLELS CLNHSESLPS 
    QDLLLGPSES NDRLSQGAYG GLSDRPSASI SPSSASIAAS HFDSMELLPP ELPPRIPIEE 
    GPPAGTVHPL SAPYPPLDTP ETATGSFLFQ GEPEGGEGDQ PLSGYPWFHG MLSRLKAAQL 
    VLTGGTGSHG VFLVRQSETR RGEYVLTFNF QGKAKHLRLS LNEEGQCRVQ HLWFQSIFDM 
    LEHFRVHPIP LESGGSSDVV LVSYVPSSQR QQEPTTSHDP PQPPEPPSWT DPPQPGAEEA 
    SRAPEVAAAA AAAAKERQEK EKAGGGGVPE ELVPVVELVP VVELEEAIAP GSKAQGAGSG 
    GDAGVPPMVQ LQQSPLGGDG EEGGHPRAIN NQYSFV

Genular Protein ID: 2272252211

Symbol: B4DLN5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

Sequence Information:

  • Length: 335
  • Mass: 36098
  • Checksum: DFFC08365A14A272
  • Sequence:
  • MPDRENTFVV KVEGPSEYIM ETVDAQHVKA WVSDIQECLS PGPCPATSPR PMTLPLAPGT 
    SFLTRENTDS LELSCLNHSE SLPSQDLLLG PSESNDRLSQ GAYGGLSDRP SASISPSSAS 
    IAASHFDSME LLPPELPPRI PIEEGPPTGT VHPLSAPYPP LDTPETATGS FLFQGEPEGG 
    EGDQPLSGYP WFHGMLSRLK AAQLVLTGGT GSHGVFLVRQ SETRRGEYVL TFNFQGKAKH 
    LRLSLNEEGQ CRVQHLWFQS IFDMLEHFRV HPIPLESGGS SDVVLVSYVP SSQRQQGREQ 
    AGSHAGVCEG DGCHPDASCT LMPFGASDCV TDHLP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.