Details for: REXO2

Gene ID: 25996

Symbol: REXO2

Ensembl ID: ENSG00000076043

Description: RNA exonuclease 2

Associated with

Other Information

Genular Protein ID: 786897776

Symbol: ORN_HUMAN

Name: Oligoribonuclease, mitochondrial

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10810093

Title: Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.

PubMed ID: 10810093

DOI: 10.1101/gr.10.5.703

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10851236

Title: The human homolog of Escherichia coli Orn degrades small single-stranded RNA and DNA oligomers.

PubMed ID: 10851236

DOI: 10.1074/jbc.m002672200

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 16682444

Title: Oligoribonuclease is a common downstream target of lithium-induced pAp accumulation in Escherichia coli and human cells.

PubMed ID: 16682444

DOI: 10.1093/nar/gkl247

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23741365

Title: REXO2 is an oligoribonuclease active in human mitochondria.

PubMed ID: 23741365

DOI: 10.1371/journal.pone.0064670

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 31588022

Title: Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.

PubMed ID: 31588022

DOI: 10.1016/j.molcel.2019.09.010

PubMed ID: 30926754

Title: Structural insights into nanoRNA degradation by human Rexo2.

PubMed ID: 30926754

DOI: 10.1261/rna.070557.119

PubMed ID: 32365187

Title: Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA.

PubMed ID: 32365187

DOI: 10.1093/nar/gkaa302

Sequence Information:

  • Length: 237
  • Mass: 26833
  • Checksum: A0343A8918B11B82
  • Sequence:
  • MLGGSLGSRL LRGVGGSHGR FGARGVREGG AAMAAGESMA QRMVWVDLEM TGLDIEKDQI 
    IEMACLITDS DLNILAEGPN LIIKQPDELL DSMSDWCKEH HGKSGLTKAV KESTITLQQA 
    EYEFLSFVRQ QTPPGLCPLA GNSVHEDKKF LDKYMPQFMK HLHYRIIDVS TVKELCRRWY 
    PEEYEFAPKK AASHRALDDI SESIKELQFY RNNIFKKKID EKKRKIIENG ENEKTVS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.