AOC1 | ENSG00000002726 | NCBI 26

Details for: AOC1

Gene ID: 26

Symbol: AOC1

Ensembl ID: ENSG00000002726

Description: amine oxidase copper containing 1

Associated with

Biological oxidations
(R-HSA-211859)
Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Metabolism
(R-HSA-1430728)
Neutrophil degranulation
(R-HSA-6798695)
Phase i - functionalization of compounds
(R-HSA-211945)
Amine metabolic process
(GO:0009308)
Bicellular tight junction
(GO:0005923)
Calcium ion binding
(GO:0005509)
Cellular response to azide
(GO:0097185)
Cellular response to copper ion
(GO:0071280)
Cellular response to copper ion starvation
(GO:0035874)
Cellular response to heparin
(GO:0071504)
Cellular response to histamine
(GO:0071420)
Copper ion binding
(GO:0005507)
Diamine oxidase activity
(GO:0052597)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Heparin binding
(GO:0008201)
Histamine oxidase activity
(GO:0052598)
Methylputrescine oxidase activity
(GO:0052599)
Peroxisome
(GO:0005777)
Plasma membrane
(GO:0005886)
Primary amine oxidase activity
(GO:0008131)
Propane-1,3-diamine oxidase activity
(GO:0052600)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Putrescine metabolic process
(GO:0009445)
Quinone binding
(GO:0048038)
Response to antibiotic
(GO:0046677)
Specific granule lumen
(GO:0035580)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Amiloride-sensitive amine oxidase [copper-containing]

Genular Protein ID: 104605540

Symbol: AOC1_HUMAN

Name: Amiloride-sensitive amine oxidase [copper-containing]

UniProtKB Accession Codes:

P19801 C9J690 Q16683 Q16684 Q56II4 Q6GU42

Database IDs:

Citations:

PubMed ID: 2217167

Title: Human kidney amiloride-binding protein: cDNA structure and functional expression.

PubMed ID: 2217167

DOI: 10.1073/pnas.87.19.7347

PubMed ID: 8182053

Title: The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter.

PubMed ID: 8182053

DOI: 10.1016/s0021-9258(17)36648-6

PubMed ID: 8595053

Title: cDNA sequences of variant forms of human placenta diamine oxidase.

PubMed ID: 8595053

DOI: 10.1007/bf02401856

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8144586

Title: Diamine oxidase is the amiloride-binding protein and is inhibited by amiloride analogues.

PubMed ID: 8144586

DOI: 10.1016/s0021-9258(17)36970-3

PubMed ID: 19764817

Title: Structure and inhibition of human diamine oxidase.

PubMed ID: 19764817

DOI: 10.1021/bi9014192

Sequence Information:

Length: 751
Mass: 85378
Checksum: 37114CD0D446639C
Sequence:

MPALGWAVAA ILMLQTAMAE PSPGTLPRKA GVFSDLSNQE LKAVHSFLWS KKELRLQPSS 
TTTMAKNTVF LIEMLLPKKY HVLRFLDKGE RHPVREARAV IFFGDQEHPN VTEFAVGPLP 
GPCYMRALSP RPGYQSSWAS RPISTAEYAL LYHTLQEATK PLHQFFLNTT GFSFQDCHDR 
CLAFTDVAPR GVASGQRRSW LIIQRYVEGY FLHPTGLELL VDHGSTDAGH WAVEQVWYNG 
KFYGSPEELA RKYADGEVDV VVLEDPLPGG KGHDSTEEPP LFSSHKPRGD FPSPIHVSGP 
RLVQPHGPRF RLEGNAVLYG GWSFAFRLRS SSGLQVLNVH FGGERIAYEV SVQEAVALYG 
GHTPAGMQTK YLDVGWGLGS VTHELAPGID CPETATFLDT FHYYDADDPV HYPRALCLFE 
MPTGVPLRRH FNSNFKGGFN FYAGLKGQVL VLRTTSTVYN YDYIWDFIFY PNGVMEAKMH 
ATGYVHATFY TPEGLRHGTR LHTHLIGNIH THLVHYRVDL DVAGTKNSFQ TLQMKLENIT 
NPWSPRHRVV QPTLEQTQYS WERQAAFRFK RKLPKYLLFT SPQENPWGHK RTYRLQIHSM 
ADQVLPPGWQ EEQAITWARY PLAVTKYRES ELCSSSIYHQ NDPWHPPVVF EQFLHNNENI 
ENEDLVAWVT VGFLHIPHSE DIPNTATPGN SVGFLLRPFN FFPEDPSLAS RDTVIVWPRD 
NGPNYVQRWI PEDRDCSMPP PFSYNGTYRP V

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: AOC1

Associated with

Other Information

Human kidney amiloride-binding protein: cDNA structure and functional expression. PubMed ID: 2217167

The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter. PubMed ID: 8182053

cDNA sequences of variant forms of human placenta diamine oxidase. PubMed ID: 8595053

The DNA sequence of human chromosome 7. PubMed ID: 12853948

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Diamine oxidase is the amiloride-binding protein and is inhibited by amiloride analogues. PubMed ID: 8144586

Structure and inhibition of human diamine oxidase. PubMed ID: 19764817