Details for: SENP3

Gene ID: 26168

Symbol: SENP3

Ensembl ID: ENSG00000161956

Description: SUMO specific peptidase 3

Associated with

Other Information

Genular Protein ID: 1763807577

Symbol: SENP3_HUMAN

Name: Sentrin-specific protease 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10806345

Title: Ubiquitin-like proteins: new wines in new bottles.

PubMed ID: 10806345

DOI: 10.1016/s0378-1119(00)00139-6

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15960975

Title: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

PubMed ID: 15960975

DOI: 10.1016/j.cell.2005.04.031

PubMed ID: 15743823

Title: Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors.

PubMed ID: 15743823

DOI: 10.1128/mcb.25.6.2273-2287.2005

PubMed ID: 16608850

Title: Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3.

PubMed ID: 16608850

DOI: 10.1074/jbc.m511658200

PubMed ID: 18259216

Title: The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing.

PubMed ID: 18259216

DOI: 10.1038/embor.2008.3

PubMed ID: 19015314

Title: Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases.

PubMed ID: 19015314

DOI: 10.1083/jcb.200807185

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19680224

Title: SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation.

PubMed ID: 19680224

DOI: 10.1038/emboj.2009.210

PubMed ID: 18946085

Title: RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin.

PubMed ID: 18946085

DOI: 10.1091/mbc.e08-05-0511

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 22872859

Title: Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.

PubMed ID: 22872859

DOI: 10.1074/mcp.m112.017194

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25406032

Title: Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage.

PubMed ID: 25406032

DOI: 10.1038/ncomms6483

PubMed ID: 32832608

Title: TIP60 K430 SUMOylation attenuates its interaction with DNA-PKcs in S-phase cells: Facilitating homologous recombination and emerging target for cancer therapy.

PubMed ID: 32832608

DOI: 10.1126/sciadv.aba7822

Sequence Information:

  • Length: 574
  • Mass: 65010
  • Checksum: E495137EE7500741
  • Sequence:
  • MKETIQGTGS WGPEPPGPGI PPAYSSPRRE RLRWPPPPKP RLKSGGGFGP DPGSGTTVPA 
    RRLPVPRPSF DASASEEEEE EEEEEDEDEE EEVAAWRLPP RWSQLGTSQR PRPSRPTHRK 
    TCSQRRRRAM RAFRMLLYSK STSLTFHWKL WGRHRGRRRG LAHPKNHLSP QQGGATPQVP 
    SPCCRFDSPR GPPPPRLGLL GALMAEDGVR GSPPVPSGPP MEEDGLRWTP KSPLDPDSGL 
    LSCTLPNGFG GQSGPEGERS LAPPDASILI SNVCSIGDHV AQELFQGSDL GMAEEAERPG 
    EKAGQHSPLR EEHVTCVQSI LDEFLQTYGS LIPLSTDEVV EKLEDIFQQE FSTPSRKGLV 
    LQLIQSYQRM PGNAMVRGFR VAYKRHVLTM DDLGTLYGQN WLNDQVMNMY GDLVMDTVPE 
    KVHFFNSFFY DKLRTKGYDG VKRWTKNVDI FNKELLLIPI HLEVHWSLIS VDVRRRTITY 
    FDSQRTLNRR CPKHIAKYLQ AEAVKKDRLD FHQGWKGYFK MNVARQNNDS DCGAFVLQYC 
    KHLALSQPFS FTQQDMPKLR RQIYKELCHC KLTV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.