Details for: INTS1
Associated with
Other Information
Genular Protein ID: 2177097756
Symbol: INT1_HUMAN
Name: Integrator complex subunit 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16421571
Title: DNA sequence and analysis of human chromosome 8.
PubMed ID: 16421571
DOI: 10.1038/nature04406
PubMed ID: 10718198
Title: Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10718198
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16239144
Title: Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
PubMed ID: 16239144
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23904267
Title: Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.
PubMed ID: 23904267
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 28542170
Title: Human mutations in integrator complex subunits link transcriptome integrity to brain development.
PubMed ID: 28542170
PubMed ID: 30622326
Title: Biallelic sequence variants in INTS1 in patients with developmental delays, cataracts, and craniofacial anomalies.
PubMed ID: 30622326
PubMed ID: 31428919
Title: Biallelic INTS1 mutations cause a rare neurodevelopmental disorder in two Chinese siblings.
PubMed ID: 31428919
Sequence Information:
- Length: 2190
- Mass: 244297
- Checksum: 342FF560BF3F61F6
- Sequence:
MNRAKPTTVR RPSAAAKPSG HPPPGDFIAL GSKGQANESK TASTLLKPAP SGLPSERKRD AAAALSSASA LTGLTKRPKL SSTPPLSALG RLAEAAVAEK RAISPSIKEP SVVPIEVLPT VLLDEIEAAE LEGNDDRIEG VLCGAVKQLK VTRAKPDSTL YLSLMYLAKI KPNIFATEGV IEALCSLLRR DASINFKAKG NSLVSVLACN LLMAAYEEDE NWPEIFVKVY IEDSLGERIW VDSPHCKTFV DNIQTAFNTR MPPRSVLLQG EAGRVAGDLG AGSSPHPSLT EEEDSQTELL IAEEKLSPEQ EGQLMPRYEE LAESVEEYVL DMLRDQLNRR QPIDNVSRNL LRLLTSTCGY KEVRLLAVQK LEMWLQNPKL TRPAQDLLMS VCMNCNTHGS EDMDVISHLI KIRLKPKVLL NHFMLCIREL LSAHKDNLGT TIKLVIFNEL SSARNPNNMQ VLYTALQHSS ELAPKFLAMV FQDLLTNKDD YLRASRALLR EIIKQTKHEI NFQAFCLGLM QERKEPQYLE MEFKERFVVH ITDVLAVSMM LGITAQVKEA GIAWDKGEKR NLEVLRSFQN QIAAIQRDAV WWLHTVVPSI SKLAPKDYVH CLHKVLFTEQ PETYYKWDNW PPESDRNFFL RLCSEVPILE DTLMRILVIG LSRELPLGPA DAMELADHLV KRAAAVQADD VEVLKVGRTQ LIDAVLNLCT YHHPENIQLP PGYQPPNLAI STLYWKAWPL LLVVAAFNPE NIGLAAWEEY PTLKMLMEMV MTNNYSYPPC TLTDEETRTE MLNRELQTAQ REKQEILAFE GHLAAASTKQ TITESSSLLL SQLTSLDPQG PPRRPPPHIL DQVKSLNQSL RLGHLLCRSR NPDFLLHIIQ RQASSQSMPW LADLVQSSEG SLDVLPVQCL CEFLLHDAVD DAASGEEDDE GESKEQKAKK RQRQQKQRQL LGRLQDLLLG PKADEQTTCE VLDYFLRRLG SSQVASRVLA MKGLSLVLSE GSLRDGEEKE PPMEEDVGDT DVLQGYQWLL RDLPRLPLFD SVRSTTALAL QQAIHMETDP QTISAYLIYL SQHTPVEEQA QHSDLALDVA RLVVERSTIM SHLFSKLSPS AASDAVLSAL LSIFSRYVRR MRQSKEGEEV YSWSESQDQV FLRWSSGETA TMHILVVHAM VILLTLGPPR ADDSEFQALL DIWFPEEKPL PTAFLVDTSE EALLLPDWLK LRMIRSEVLR LVDAALQDLE PQQLLLFVQS FGIPVSSMSK LLQFLDQAVA HDPQTLEQNI MDKNYMAHLV EVQHERGASG GQTFHSLLTA SLPPRRDSTE APKPKSSPEQ PIGQGRIRVG TQLRVLGPED DLAGMFLQIF PLSPDPRWQS SSPRPVALAL QQALGQELAR VVQGSPEVPG ITVRVLQALA TLLSSPHGGA LVMSMHRSHF LACPLLRQLC QYQRCVPQDT GFSSLFLKVL LQMLQWLDSP GVEGGPLRAQ LRMLASQASA GRRLSDVRGG LLRLAEALAF RQDLEVVSST VRAVIATLRS GEQCSVEPDL ISKVLQGLIE VRSPHLEELL TAFFSATADA ASPFPACKPV VVVSSLLLQE EEPLAGGKPG ADGGSLEAVR LGPSSGLLVD WLEMLDPEVV SSCPDLQLRL LFSRRKGKGQ AQVPSFRPYL LTLFTHQSSW PTLHQCIRVL LGKSREQRFD PSASLDFLWA CIHVPRIWQG RDQRTPQKRR EELVLRVQGP ELISLVELIL AEAETRSQDG DTAACSLIQA RLPLLLSCCC GDDESVRKVT EHLSGCIQQW GDSVLGRRCR DLLLQLYLQR PELRVPVPEV LLHSEGAASS SVCKLDGLIH RFITLLADTS DSRALENRGA DASMACRKLA VAHPLLLLRH LPMIAALLHG RTHLNFQEFR QQNHLSCFLH VLGLLELLQP HVFRSEHQGA LWDCLLSFIR LLLNYRKSSR HLAAFINKFV QFIHKYITYN APAAISFLQK HADPLHDLSF DNSDLVMLKS LLAGLSLPSR DDRTDRGLDE EGEEESSAGS LPLVSVSLFT PLTAAEMAPY MKRLSRGQTV EDLLEVLSDI DEMSRRRPEI LSFFSTNLQR LMSSAEECCR NLAFSLALRS MQNSPSIAAA FLPTFMYCLG SQDFEVVQTA LRNLPEYALL CQEHAAVLLH RAFLVGMYGQ MDPSAQISEA LRILHMEAVM
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.