Details for: AMD1

Gene ID: 262

Symbol: AMD1

Ensembl ID: ENSG00000123505

Description: adenosylmethionine decarboxylase 1

Associated with

Other Information

Genular Protein ID: 3831507987

Symbol: DCAM_HUMAN

Name: S-adenosylmethionine decarboxylase proenzyme

UniProtKB Accession Codes:

P17707 E1P5F7 Q5VXN4 Q5VXN6 Q9BWK4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 5 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EC 1 EMBL 8 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 29 PDBsum 25 PIR 1 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 1 SABIO-RK 1 SMR 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2460457

Title: Structure and regulation of mammalian S-adenosylmethionine decarboxylase.

PubMed ID: 2460457

DOI: 10.1016/s0021-9258(18)37495-7

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2687270

Title: Site of pyruvate formation and processing of mammalian S-adenosylmethionine decarboxylase proenzyme.

PubMed ID: 2687270

DOI: 10.1016/s0021-9258(19)30047-x

PubMed ID: 1917972

Title: Amino acid residues necessary for putrescine stimulation of human S-adenosylmethionine decarboxylase proenzyme processing and catalytic activity.

PubMed ID: 1917972

DOI: 10.1016/s0021-9258(18)55089-4

PubMed ID: 10574985

Title: Mechanistic studies of the processing of human S-adenosylmethionine decarboxylase proenzyme. Isolation of an ester intermediate.

PubMed ID: 10574985

DOI: 10.1074/jbc.274.49.35059

PubMed ID: 10029540

Title: Role of cysteine-82 in the catalytic mechanism of human S-adenosylmethionine decarboxylase.

PubMed ID: 10029540

DOI: 10.1021/bi9825201

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 10378277

Title: The crystal structure of human S-adenosylmethionine decarboxylase at 2.25-A resolution reveals a novel fold.

PubMed ID: 10378277

DOI: 10.1016/s0969-2126(99)80074-4

PubMed ID: 11583147

Title: The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase.

PubMed ID: 11583147

DOI: 10.1021/bi010735w

Sequence Information:

  • Length: 334
  • Mass: 38340
  • Checksum: 1BB433AF412C9179
  • Sequence:
    • MEAAHFFEGT EKLLEVWFSR QQPDANQGSG DLRTIPRSEW DILLKDVQCS IISVTKTDKQ 
EAYVLSESSM FVSKRRFILK TCGTTLLLKA LVPLLKLARD YSGFDSIQSF FYSRKNFMKP 
SHQGYPHRNF QEEIEFLNAI FPNGAAYCMG RMNSDCWYLY TLDFPESRVI SQPDQTLEIL 
MSELDPAVMD QFYMKDGVTA KDVTRESGIR DLIPGSVIDA TMFNPCGYSM NGMKSDGTYW 
TIHITPEPEF SYVSFETNLS QTSYDDLIRK VVEVFKPGKF VTTLFVNQSS KCRTVLASPQ 
KIEGFKRLDC QSAMFNDYNF VFTSFAKKQQ QQQS

Genular Protein ID: 446231405

Symbol: A0A088AWN0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A088AWN0

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 GenomeRNAi 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 5 PeptideAtlas 1 Pfam 1 RefSeq 2 SMR 1 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 305
  • Mass: 34976
  • Checksum: D3FC9C01EC59ADD8
  • Sequence:
    • MEAAHFFEGT EKLLEVWFSR QQPDANQGSG DLRTIPSESS MFVSKRRFIL KTCGTTLLLK 
ALVPLLKLAR DYSGFDSIQS FFYSRKNFMK PSHQGYPHRN FQEEIEFLNA IFPNGAAYCM 
GRMNSDCWYL YTLDFPESRV ISQPDQTLEI LMSELDPAVM DQFYMKDGVT AKDVTRESGI 
RDLIPGSVID ATMFNPCGYS MNGMKSDGTY WTIHITPEPE FSYVSFETNL SQTSYDDLIR 
KVVEVFKPGK FVTTLFVNQS SKCRTVLASP QKIEGFKRLD CQSAMFNDYN FVFTSFAKKQ 
QQQQS

Genular Protein ID: 1808163191

Symbol: Q6N0B2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6N0B2

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 5 DNASU 1 EC 1 EMBL 2 GO 3 Gene3D 1 GenomeRNAi 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 5 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 1 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 334
  • Mass: 38287
  • Checksum: 1BB43573312C9EDC
  • Sequence:
    • MEAAHFFEGT EKLLEVWFSR QQPDANQGSG DLRTIPRSEW DILLKDVQCS IISVTKTDKQ 
EAYVLSESSM FVSKRCFILK TCGTTLLLKA LVPLLKLARD YSGFDSIQSF FYSRKNFMKP 
SHQGYPHRNF QEEIEFLNAI FPNGAAYCMG RMNSDCWYLY TLDFPESRVI SQPDQTLEIL 
MSELDPAVMD QFYMKDGVTA KDVTRESGIR DLIPGSVIDA TMFNPCGYSM NGMKSDGTYW 
TIHITPEPEF SYVSFETNLS QTSYDDLIRK VVEVFKPGKF VTTLFVNQSS KCRTVLASPQ 
KIEGFKRLDC QSAMFNDYNF VFTSFAKKQQ QQQS

Genular Protein ID: 334989290

Symbol: Q5VXN5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5VXN5 A6NNH3 B4DTR6

Database IDs:

ARBA 5 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 EPD 1 Ensembl 3 GO 3 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 3 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 PANTHER 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SUPFAM 1 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

Sequence Information:

  • Length: 265
  • Mass: 30497
  • Checksum: 6B1151E4A567E5D7
  • Sequence:
    • MFVSKRRFIL KTCGTTLLLK ALVPLLKLAR DYSGFDSIQS FFYSRKNFMK PSHQGYPHRN 
FQEEIEFLNA IFPNGAAYCM GRMNSDCWYL YTLDFPESRV ISQPDQTLEI LMSELDPAVM 
DQFYMKDGVT AKDVTRESGI RDLIPGSVID ATMFNPCGYS MNGMKSDGTY WTIHITPEPE 
FSYVSFETNL SQTSYDDLIR KVVEVFKPGK FVTTLFVNQS SKCRTVLASP QKIEGFKRLD 
CQSAMFNDYN FVFTSFAKKQ QQQQS

Genular Protein ID: 714824002

Symbol: B4DZ60_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DZ60

Database IDs:

ARBA 3 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 EPD 1 Ensembl 2 GO 3 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 2 KEGG 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 3 SUPFAM 1 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

Sequence Information:

  • Length: 214
  • Mass: 24465
  • Checksum: CF441EB294491E7A
  • Sequence:
    • MEAAHFFEGT EKLLEVWFSR QQPDANQGSG DLRTIPRYLY TLDFPESRVI SQPDQTLEIL 
MSELDPAVMD QFYMKDGVTA KDVTRESGIR DLIPGSVIDA TMFNPCGYSM NGMKSDGTYW 
TIHITPEPEF SYVSFETNLS QTSYDDLIRK VVEVFKPGKF VTTLFVNQSS KCRTVLASPQ 
KIEGFKRLDC QSAMFNDYNF VFTSFAKKQQ QQQS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.