Details for: AMD1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 357.4845
Cell Significance Index: -55.6100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 206.2541
Cell Significance Index: -52.3200 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 169.5118
Cell Significance Index: -69.8300 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 145.9684
Cell Significance Index: -68.9200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 139.0745
Cell Significance Index: -56.5000 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 125.3341
Cell Significance Index: -64.4700 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 59.8905
Cell Significance Index: -57.1800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 55.3426
Cell Significance Index: -68.2400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 23.5884
Cell Significance Index: -63.1900 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 19.9547
Cell Significance Index: -61.2900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 18.2904
Cell Significance Index: -72.1800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.0234
Cell Significance Index: -17.5600 - Cell Name: odontoblast (CL0000060)
Fold Change: 3.3349
Cell Significance Index: 427.5100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.8768
Cell Significance Index: 39.2500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.8529
Cell Significance Index: 197.3000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 2.7175
Cell Significance Index: 441.9700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 2.6574
Cell Significance Index: 120.4500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.1196
Cell Significance Index: 99.6200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.1169
Cell Significance Index: 57.6200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.9931
Cell Significance Index: 245.0700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.9068
Cell Significance Index: 54.6600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.5500
Cell Significance Index: 310.9200 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 1.5095
Cell Significance Index: 9.2900 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.4803
Cell Significance Index: 191.2500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.4315
Cell Significance Index: 284.0800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.4118
Cell Significance Index: 91.0900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.3238
Cell Significance Index: 46.0000 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.3216
Cell Significance Index: 23.3600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.2168
Cell Significance Index: 143.5000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.1754
Cell Significance Index: 641.9200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.1341
Cell Significance Index: 84.5200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.0948
Cell Significance Index: 197.3500 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.0939
Cell Significance Index: 11.3200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.0728
Cell Significance Index: 147.3300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.0713
Cell Significance Index: 49.9500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.9977
Cell Significance Index: 26.6400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.9671
Cell Significance Index: 427.5800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.9464
Cell Significance Index: 49.6900 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.9043
Cell Significance Index: 6.9700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.7534
Cell Significance Index: 270.2200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.6924
Cell Significance Index: 15.0000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.6757
Cell Significance Index: 47.7900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5780
Cell Significance Index: 521.9200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.4450
Cell Significance Index: 23.1800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2218
Cell Significance Index: 13.9800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1973
Cell Significance Index: 5.5200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1847
Cell Significance Index: 6.4900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1203
Cell Significance Index: 6.2500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0725
Cell Significance Index: 13.8000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0659
Cell Significance Index: 1.9000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0556
Cell Significance Index: 104.6500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0440
Cell Significance Index: 33.2700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0173
Cell Significance Index: 12.6700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0046
Cell Significance Index: 2.9100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0046
Cell Significance Index: 6.2000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0031
Cell Significance Index: -5.6700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0036
Cell Significance Index: -5.5500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0551
Cell Significance Index: -25.0100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0816
Cell Significance Index: -4.5800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0818
Cell Significance Index: -60.6100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0920
Cell Significance Index: -9.4000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0996
Cell Significance Index: -7.6400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1040
Cell Significance Index: -6.9900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1041
Cell Significance Index: -17.7800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1185
Cell Significance Index: -66.8300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1304
Cell Significance Index: -81.4300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1887
Cell Significance Index: -11.6000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2096
Cell Significance Index: -60.3000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2642
Cell Significance Index: -38.4100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.2936
Cell Significance Index: -3.5000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.3001
Cell Significance Index: -29.6900 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3194
Cell Significance Index: -5.3500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3787
Cell Significance Index: -79.7600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3908
Cell Significance Index: -45.5500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4071
Cell Significance Index: -46.6400 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.5288
Cell Significance Index: -3.2000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5840
Cell Significance Index: -46.2500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.5927
Cell Significance Index: -61.7100 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.6049
Cell Significance Index: -11.1800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.6088
Cell Significance Index: -26.9300 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.6262
Cell Significance Index: -16.4700 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.6768
Cell Significance Index: -17.2900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.7802
Cell Significance Index: -46.8400 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.7969
Cell Significance Index: -16.6800 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.8028
Cell Significance Index: -9.1200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.8128
Cell Significance Index: -23.8700 - Cell Name: peg cell (CL4033014)
Fold Change: -0.8284
Cell Significance Index: -19.1400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.8947
Cell Significance Index: -33.8800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.9615
Cell Significance Index: -25.7200 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -1.1153
Cell Significance Index: -40.9400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.1223
Cell Significance Index: -68.8100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.1249
Cell Significance Index: -36.0300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -1.1748
Cell Significance Index: -59.3700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -1.1861
Cell Significance Index: -25.2600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -1.2657
Cell Significance Index: -36.1200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.3129
Cell Significance Index: -32.8200 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -1.4239
Cell Significance Index: -14.7400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.4399
Cell Significance Index: -38.5800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -1.4558
Cell Significance Index: -34.9200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -1.6291
Cell Significance Index: -47.9900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3831507987
Symbol: DCAM_HUMAN
Name: S-adenosylmethionine decarboxylase proenzyme
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2460457
Title: Structure and regulation of mammalian S-adenosylmethionine decarboxylase.
PubMed ID: 2460457
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2687270
Title: Site of pyruvate formation and processing of mammalian S-adenosylmethionine decarboxylase proenzyme.
PubMed ID: 2687270
PubMed ID: 1917972
Title: Amino acid residues necessary for putrescine stimulation of human S-adenosylmethionine decarboxylase proenzyme processing and catalytic activity.
PubMed ID: 1917972
PubMed ID: 10574985
Title: Mechanistic studies of the processing of human S-adenosylmethionine decarboxylase proenzyme. Isolation of an ester intermediate.
PubMed ID: 10574985
PubMed ID: 10029540
Title: Role of cysteine-82 in the catalytic mechanism of human S-adenosylmethionine decarboxylase.
PubMed ID: 10029540
DOI: 10.1021/bi9825201
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 10378277
Title: The crystal structure of human S-adenosylmethionine decarboxylase at 2.25-A resolution reveals a novel fold.
PubMed ID: 10378277
PubMed ID: 11583147
Title: The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase.
PubMed ID: 11583147
DOI: 10.1021/bi010735w
Sequence Information:
- Length: 334
- Mass: 38340
- Checksum: 1BB433AF412C9179
- Sequence:
MEAAHFFEGT EKLLEVWFSR QQPDANQGSG DLRTIPRSEW DILLKDVQCS IISVTKTDKQ EAYVLSESSM FVSKRRFILK TCGTTLLLKA LVPLLKLARD YSGFDSIQSF FYSRKNFMKP SHQGYPHRNF QEEIEFLNAI FPNGAAYCMG RMNSDCWYLY TLDFPESRVI SQPDQTLEIL MSELDPAVMD QFYMKDGVTA KDVTRESGIR DLIPGSVIDA TMFNPCGYSM NGMKSDGTYW TIHITPEPEF SYVSFETNLS QTSYDDLIRK VVEVFKPGKF VTTLFVNQSS KCRTVLASPQ KIEGFKRLDC QSAMFNDYNF VFTSFAKKQQ QQQS
Genular Protein ID: 1808163191
Symbol: Q6N0B2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 334
- Mass: 38287
- Checksum: 1BB43573312C9EDC
- Sequence:
MEAAHFFEGT EKLLEVWFSR QQPDANQGSG DLRTIPRSEW DILLKDVQCS IISVTKTDKQ EAYVLSESSM FVSKRCFILK TCGTTLLLKA LVPLLKLARD YSGFDSIQSF FYSRKNFMKP SHQGYPHRNF QEEIEFLNAI FPNGAAYCMG RMNSDCWYLY TLDFPESRVI SQPDQTLEIL MSELDPAVMD QFYMKDGVTA KDVTRESGIR DLIPGSVIDA TMFNPCGYSM NGMKSDGTYW TIHITPEPEF SYVSFETNLS QTSYDDLIRK VVEVFKPGKF VTTLFVNQSS KCRTVLASPQ KIEGFKRLDC QSAMFNDYNF VFTSFAKKQQ QQQS
Genular Protein ID: 714824002
Symbol: B4DZ60_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
Sequence Information:
- Length: 214
- Mass: 24465
- Checksum: CF441EB294491E7A
- Sequence:
MEAAHFFEGT EKLLEVWFSR QQPDANQGSG DLRTIPRYLY TLDFPESRVI SQPDQTLEIL MSELDPAVMD QFYMKDGVTA KDVTRESGIR DLIPGSVIDA TMFNPCGYSM NGMKSDGTYW TIHITPEPEF SYVSFETNLS QTSYDDLIRK VVEVFKPGKF VTTLFVNQSS KCRTVLASPQ KIEGFKRLDC QSAMFNDYNF VFTSFAKKQQ QQQS
Genular Protein ID: 446231405
Symbol: A0A088AWN0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 305
- Mass: 34976
- Checksum: D3FC9C01EC59ADD8
- Sequence:
MEAAHFFEGT EKLLEVWFSR QQPDANQGSG DLRTIPSESS MFVSKRRFIL KTCGTTLLLK ALVPLLKLAR DYSGFDSIQS FFYSRKNFMK PSHQGYPHRN FQEEIEFLNA IFPNGAAYCM GRMNSDCWYL YTLDFPESRV ISQPDQTLEI LMSELDPAVM DQFYMKDGVT AKDVTRESGI RDLIPGSVID ATMFNPCGYS MNGMKSDGTY WTIHITPEPE FSYVSFETNL SQTSYDDLIR KVVEVFKPGK FVTTLFVNQS SKCRTVLASP QKIEGFKRLD CQSAMFNDYN FVFTSFAKKQ QQQQS
Genular Protein ID: 334989290
Symbol: Q5VXN5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
Sequence Information:
- Length: 265
- Mass: 30497
- Checksum: 6B1151E4A567E5D7
- Sequence:
MFVSKRRFIL KTCGTTLLLK ALVPLLKLAR DYSGFDSIQS FFYSRKNFMK PSHQGYPHRN FQEEIEFLNA IFPNGAAYCM GRMNSDCWYL YTLDFPESRV ISQPDQTLEI LMSELDPAVM DQFYMKDGVT AKDVTRESGI RDLIPGSVID ATMFNPCGYS MNGMKSDGTY WTIHITPEPE FSYVSFETNL SQTSYDDLIR KVVEVFKPGK FVTTLFVNQS SKCRTVLASP QKIEGFKRLD CQSAMFNDYN FVFTSFAKKQ QQQQS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.