FBXO6 | ENSG00000116663 | NCBI 26270

Details for: FBXO6

Gene ID: 26270

Symbol: FBXO6

Ensembl ID: ENSG00000116663

Description: F-box protein 6

Associated with

Adaptive immune system
(R-HSA-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-HSA-983168)
Association of tric/cct with target proteins during biosynthesis
(R-HSA-390471)
Chaperonin-mediated protein folding
(R-HSA-390466)
Class i mhc mediated antigen processing & presentation
(R-HSA-983169)
Immune system
(R-HSA-168256)
Metabolism of proteins
(R-HSA-392499)
Neddylation
(R-HSA-8951664)
Post-translational protein modification
(R-HSA-597592)
Protein folding
(R-HSA-391251)
Carbohydrate binding
(GO:0030246)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna damage checkpoint signaling
(GO:0000077)
Dna repair
(GO:0006281)
Endoplasmic reticulum quality control compartment
(GO:0044322)
Erad pathway
(GO:0036503)
Glycoprotein catabolic process
(GO:0006516)
Protein binding
(GO:0005515)
Protein ubiquitination
(GO:0016567)
Proteolysis
(GO:0006508)
Response to unfolded protein
(GO:0006986)
Scf-dependent proteasomal ubiquitin-dependent protein catabolic process
(GO:0031146)
Scf ubiquitin ligase complex
(GO:0019005)
Ubiquitin protein ligase activity
(GO:0061630)

Other Information

Proteins

F-box only protein 6

Genular Protein ID: 3507707543

Symbol: FBX6_HUMAN

Name: F-box only protein 6

UniProtKB Accession Codes:

Q9NRD1 B1AK42 B2RC88 Q9UKT3

Database IDs:

Citations:

PubMed ID: 10531035

Title: Identification of a family of human F-box proteins.

PubMed ID: 10531035

DOI: 10.1016/s0960-9822(00)80020-2

PubMed ID: 10945468

Title: cDNA cloning and expression analysis of new members of the mammalian F-box protein family.

PubMed ID: 10945468

DOI: 10.1006/geno.2000.6211

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18203720

Title: Diversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligases.

PubMed ID: 18203720

DOI: 10.1074/jbc.m709508200

PubMed ID: 19716789

Title: The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.

PubMed ID: 19716789

DOI: 10.1016/j.molcel.2009.06.030

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

Sequence Information:

Length: 293
Mass: 33933
Checksum: EA4235CD9CCD80FF
Sequence:

MDAPHSKAAL DSINELPENI LLELFTHVPA RQLLLNCRLV CSLWRDLIDL MTLWKRKCLR 
EGFITKDWDQ PVADWKIFYF LRSLHRNLLR NPCAEEDMFA WQIDFNGGDR WKVESLPGAH 
GTDFPDPKVK KYFVTSYEMC LKSQLVDLVA EGYWEELLDT FRPDIVVKDW FAARADCGCT 
YQLKVQLASA DYFVLASFEP PPVTIQQWNN ATWTEVSYTF SDYPRGVRYI LFQHGGRDTQ 
YWAGWYGPRV TNSSIVVSPK MTRNQASSEA QPGQKHGQEE AAQSPYRAVV QIF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: FBXO6

Associated with

Other Information

Identification of a family of human F-box proteins. PubMed ID: 10531035

cDNA cloning and expression analysis of new members of the mammalian F-box protein family. PubMed ID: 10945468

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Diversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligases. PubMed ID: 18203720

The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. PubMed ID: 19716789

Initial characterization of the human central proteome. PubMed ID: 21269460

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163