Details for: VPS33B

Gene ID: 26276

Symbol: VPS33B

Ensembl ID: ENSG00000184056

Description: VPS33B late endosome and lysosome associated

Associated with

Other Information

Genular Protein ID: 1094132622

Symbol: VP33B_HUMAN

Name: Vacuolar protein sorting-associated protein 33B

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10894945

Title: Cloning, mapping and expression analysis of VPS33B, the human orthologue of rat Vps33b.

PubMed ID: 10894945

DOI: 10.1159/000015571

PubMed ID: 11250079

Title: Molecular cloning and characterization of human VPS18, VPS11, VPS16, and VPS33.

PubMed ID: 11250079

DOI: 10.1016/s0378-1119(01)00333-x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18474358

Title: Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B.

PubMed ID: 18474358

DOI: 10.1016/j.chom.2008.03.008

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19109425

Title: SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.

PubMed ID: 19109425

DOI: 10.1091/mbc.e08-07-0728

PubMed ID: 20190753

Title: Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

PubMed ID: 20190753

DOI: 10.1038/ng.538

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21411634

Title: Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells.

PubMed ID: 21411634

DOI: 10.1091/mbc.e10-10-0799

PubMed ID: 22753090

Title: Associations among genotype, clinical phenotype, and intracellular localization of trafficking proteins in ARC syndrome.

PubMed ID: 22753090

DOI: 10.1002/humu.22155

PubMed ID: 23918659

Title: Vps33b pathogenic mutations preferentially affect VIPAS39/SPE-39-positive endosomes.

PubMed ID: 23918659

DOI: 10.1093/hmg/ddt378

PubMed ID: 23901104

Title: Structural basis of Vps33A recruitment to the human HOPS complex by Vps16.

PubMed ID: 23901104

DOI: 10.1073/pnas.1307074110

PubMed ID: 15052268

Title: Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome.

PubMed ID: 15052268

DOI: 10.1038/ng1325

PubMed ID: 18853461

Title: Molecular investigations to improve diagnostic accuracy in patients with ARC syndrome.

PubMed ID: 18853461

DOI: 10.1002/humu.20900

PubMed ID: 28017832

Title: Autosomal Recessive Keratoderma-Ichthyosis-Deafness (ARKID) Syndrome Is Caused by VPS33B Mutations Affecting Rab Protein Interaction and Collagen Modification.

PubMed ID: 28017832

DOI: 10.1016/j.jid.2016.12.010

PubMed ID: 30561130

Title: Novel VPS33B mutation in a patient with autosomal recessive keratoderma-ichthyosis-deafness syndrome.

PubMed ID: 30561130

DOI: 10.1002/ajmg.a.40634

PubMed ID: 31479177

Title: Novel missense mutation in VPS33B is associated with isolated low gamma-glutamyltransferase cholestasis: Attenuated, incomplete phenotype of arthrogryposis, renal dysfunction, and cholestasis syndrome.

PubMed ID: 31479177

DOI: 10.1002/humu.23770

Sequence Information:

  • Length: 617
  • Mass: 70585
  • Checksum: BD7DB97E1FEB1D32
  • Sequence:
  • MAFPHRPDAP ELPDFSMLKR LARDQLIYLL EQLPGKKDLF IEADLMSPLD RIANVSILKQ 
    HEVDKLYKVE NKPALSSNEQ LCFLVRPRIK NMRYIASLVN ADKLAGRTRK YKVIFSPQKF 
    YACEMVLEEE GIYGDVSCDE WAFSLLPLDV DLLSMELPEF FRDYFLEGDQ RWINTVAQAL 
    HLLSTLYGPF PNCYGIGRCA KMAYELWRNL EEEEDGETKG RRPEIGHIFL LDRDVDFVTA 
    LCSQVVYEGL VDDTFRIKCG SVDFGPEVTS SDKSLKVLLN AEDKVFNEIR NEHFSNVFGF 
    LSQKARNLQA QYDRRRGMDI KQMKNFVSQE LKGLKQEHRL LSLHIGACES IMKKKTKQDF 
    QELIKTEHAL LEGFNIREST SYIEEHIDRQ VSPIESLRLM CLLSITENGL IPKDYRSLKT 
    QYLQSYGPEH LLTFSNLRRA GLLTEQAPGD TLTAVESKVS KLVTDKAAGK ITDAFSSLAK 
    RSNFRAISKK LNLIPRVDGE YDLKVPRDMA YVFGGAYVPL SCRIIEQVLE RRSWQGLDEV 
    VRLLNCSDFA FTDMTKEDKA SSESLRLILV VFLGGCTFSE ISALRFLGRE KGYRFIFLTT 
    AVTNSARLME AMSEVKA

Genular Protein ID: 3927237187

Symbol: F5H008_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 590
  • Mass: 67606
  • Checksum: 929FDF9128B3FD5C
  • Sequence:
  • MAFPHRPDAP ELPDFSMLKR LARDQLIYLL EQQHEVDKLY KVENKPALSS NEQLCFLVRP 
    RIKNMRYIAS LVNADKLAGR TRKYKVIFSP QKFYACEMVL EEEGIYGDVS CDEWAFSLLP 
    LDVDLLSMEL PEFFRDYFLE GDQRWINTVA QALHLLSTLY GPFPNCYGIG RCAKMAYELW 
    RNLEEEEDGE TKGRRPEIGH IFLLDRDVDF VTALCSQVVY EGLVDDTFRI KCGSVDFGPE 
    VTSSDKSLKV LLNAEDKVFN EIRNEHFSNV FGFLSQKARN LQAQYDRRRG MDIKQMKNFV 
    SQELKGLKQE HRLLSLHIGA CESIMKKKTK QDFQELIKTE HALLEGFNIR ESTSYIEEHI 
    DRQVSPIESL RLMCLLSITE NGLIPKDYRS LKTQYLQSYG PEHLLTFSNL RRAGLLTEQA 
    PGDTLTAVES KVSKLVTDKA AGKITDAFSS LAKRSNFRAI SKKLNLIPRV DGEYDLKVPR 
    DMAYVFGGAY VPLSCRIIEQ VLERRSWQGL DEVVRLLNCS DFAFTDMTKE DKASSESLRL 
    ILVVFLGGCT FSEISALRFL GREKGYRFIF LTTAVTNSAR LMEAMSEVKA

Genular Protein ID: 319155589

Symbol: B7Z1N4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 590
  • Mass: 67636
  • Checksum: 938B8ED43CF2F940
  • Sequence:
  • MAFPHRPDAP ELPDFSMLKR LARDQLIYLL EQQHEVDKLY KVENKPALSS NEQLCFLVRP 
    RIKNMRYIAS LVNADKLAGR TRKYKVIFSP QKFYACEMVL EEEGIYGDVS CDEWAFSLLP 
    LDVDLLSMEL PEFFRDYFLE GDQRWINTVA QALHLLSTLY GPFPNCYGIG RCAKMAYELW 
    RNLEEEEDGE TKGRRPEIGH IFLLDRDVDF VTALCSQVVY EGLVDDTFRI KCGSVDFGPE 
    VTSSDKSLKV LLNAEDKVFN EIRNEHFSNV FGFLSQKARN LQAQYDRRRG MDIKQMKNFV 
    SQELKGLKQE HRLLSLHIGA CESIMKKKTK QDFQELIKTE HALLEGFNIR ESTSYIEEHI 
    DRQVSPIESL RLMCLLSITE NGLIPKDYRS LKTQYLQSYG PEHLLTFSNL RRAGLLTEQA 
    PGDTLTAVES KVSKLVTDKA AGKITDAFSS LAKRSNFRAI SKKLNLIPRV DGEYDLKVPR 
    DMAYVFSGAY VPLSCRIIEQ VLERRSWQGL DEVVRLLNCS DFAFTDMTKE DKASSESLRL 
    ILVVFLGGCT FSEISALRFL GREKGYRFIF LTTAVTNSAR LMEAMSEVKA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.