Details for: Clcn7

Gene ID: 26373

Symbol: Clcn7

Ensembl ID: ENSMUSG00000036636

Description: chloride channel, voltage-sensitive 7

Associated with

Other Information

Genular Protein ID: 3836215835

Symbol: CLCN7_MOUSE

Name: H(+)/Cl(-) exchange transporter 7

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11207362

Title: Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man.

PubMed ID: 11207362

DOI: 10.1016/s0092-8674(01)00206-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16525474

Title: ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function.

PubMed ID: 16525474

DOI: 10.1038/nature04535

PubMed ID: 19661288

Title: Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7.

PubMed ID: 19661288

DOI: 10.1096/fj.09-130880

PubMed ID: 31155284

Title: Lysosomal Storage and Albinism Due to Effects of a De Novo CLCN7 Variant on Lysosomal Acidification.

PubMed ID: 31155284

DOI: 10.1016/j.ajhg.2019.04.008

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

Sequence Information:

  • Length: 803
  • Mass: 88713
  • Checksum: A7D6DA5791DAA48C
  • Sequence:
  • MANVSKKVSW SGRDRDDEEG APLLRRTGQP DEETPLLNGA GPGARQSHSA LFRIGQMNNV 
    ELDDELLDPE VDPPHTFPKE IPHNEKLLSL KYESLDYDNS ENQLFLEEER RINHTAFRTV 
    EIKRWVICAL IGILTGLVAC FIDIVVENLA GLKYRVIKDN IDKFTEKGGL SFSLLLWATL 
    NSAFVLVGSV IVAFIEPVAA GSGIPQIKCF LNGVKIPHVV RLKTLVIKVS GVILSVVGGL 
    AVGKEGPMIH SGSVIAAGIS QGRSTSLKRD FKIFEYFRRD TEKRDFVSAG AAAGVSAAFG 
    APVGGVLFSL EEGASFWNQF LTWRIFFASM ISTFTLNFVL SIYHGNMWDL SSPGLINFGR 
    FDSEKMAYTI HEIPVFIAMG VVGGILGAVF NALNYWLTMF RIRYIHRPCL QVIEAMLVAA 
    VTATVAFVLI YSSRDCQPLQ GSSMSYPLQL FCADGEYNSM AAAFFNTPEK SVVSLFHDPP 
    GSYNPMTLGL FTLVYFFLAC WTYGLTVSAG VFIPSLLIGA AWGRLFGISL SYLTGAAIWA 
    DPGKYALMGA AAQLGGIVRM TLSLTVIMME ATSNVTYGFP IMLVLMTAKI VGDVFIEGLY 
    DMHIQLQSVP FLHWEAPVTS HSLTAREVMS TPVTCLRRRE KVGIIVDVLS DTASNHNGFP 
    VVEDVGDTQP ARLQGLILRS QLIVLLKHKV FVERSNMGLV QRRLRLKDFR DAYPRFPPIQ 
    SIHVSQDERE CTMDLSEFMN PSPYTVPQEA SLPRVFKLFR ALGLRHLVVV DNHNQVVGLV 
    TRKDLARYRL GKGGLEELSL AQT

Genular Protein ID: 1018993033

Symbol: E9PYL4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 783
  • Mass: 86496
  • Checksum: 1A4C9F4A63AC51BD
  • Sequence:
  • MQGILTGPLW ESPPETPPPS AEEGPQSHSA LFRIGQMNNV ELDDELLDPE VDPPHTFPKE 
    IPHNEKLLSL KYESLDYDNS ENQLFLEEER RINHTAFRTV EIKRWVICAL IGILTGLVAC 
    FIDIVVENLA GLKYRVIKDN IDKFTEKGGL SFSLLLWATL NSAFVLVGSV IVAFIEPVAA 
    GSGIPQIKCF LNGVKIPHVV RLKTLVIKVS GVILSVVGGL AVGKEGPMIH SGSVIAAGIS 
    QGRSTSLKRD FKIFEYFRRD TEKRDFVSAG AAAGVSAAFG APVGGVLFSL EEGASFWNQF 
    LTWRIFFASM ISTFTLNFVL SIYHGNMWDL SSPGLINFGR FDSEKMAYTI HEIPVFIAMG 
    VVGGILGAVF NALNYWLTMF RIRYIHRPCL QVIEAMLVAA VTATVAFVLI YSSRDCQPLQ 
    GSSMSYPLQL FCADGEYNSM AAAFFNTPEK SVVSLFHDPP GSYNPMTLGL FTLVYFFLAC 
    WTYGLTVSAG VFIPSLLIGA AWGRLFGISL SYLTGAAIWA DPGKYALMGA AAQLGGIVRM 
    TLSLTVIMME ATSNVTYGFP IMLVLMTAKI VGDVFIEGLY DMHIQLQSVP FLHWEAPVTS 
    HSLTAREVMS TPVTCLRRRE KVGIIVDVLS DTASNHNGFP VVEDVGDTQP ARLQGLILRS 
    QLIVLLKHKV FVERSNMGLV QRRLRLKDFR DAYPRFPPIQ SIHVSQDERE CTMDLSEFMN 
    PSPYTVPQEA SLPRVFKLFR ALGLRHLVVV DNHNQVVGLV TRKDLARYRL GKGGLEELSL 
    AQT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.