Details for: Fto
Associated with
Other Information
Genular Protein ID: 4104227660
Symbol: FTO_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10501967
Title: Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation.
PubMed ID: 10501967
PubMed ID: 14621295
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
PubMed ID: 14621295
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17991826
Title: The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase.
PubMed ID: 17991826
PubMed ID: 18775698
Title: Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO.
PubMed ID: 18775698
PubMed ID: 19234441
Title: Inactivation of the Fto gene protects from obesity.
PubMed ID: 19234441
DOI: 10.1038/nature07848
PubMed ID: 19680540
Title: A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.
PubMed ID: 19680540
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 21076408
Title: Overexpression of Fto leads to increased food intake and results in obesity.
PubMed ID: 21076408
DOI: 10.1038/ng.713
PubMed ID: 24807221
Title: Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice.
PubMed ID: 24807221
PubMed ID: 24646999
Title: Obesity-associated variants within FTO form long-range functional connections with IRX3.
PubMed ID: 24646999
DOI: 10.1038/nature13138
PubMed ID: 23817550
Title: The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.
PubMed ID: 23817550
DOI: 10.1038/nn.3449
PubMed ID: 23300482
Title: Adult onset global loss of the fto gene alters body composition and metabolism in the mouse.
PubMed ID: 23300482
PubMed ID: 28002401
Title: Reversible methylation of m6Am in the 5' cap controls mRNA stability.
PubMed ID: 28002401
DOI: 10.1038/nature21022
Sequence Information:
- Length: 502
- Mass: 58007
- Checksum: 69223B824028D872
- Sequence:
MKRVQTAEER EREAKKLRLL EELEDTWLPY LTPKDDEFYQ QWQLKYPKLV FREAGSIPEE LHKEVPEAFL TLHKHGCLFR DVVRIQGKDV LTPVSRILIG DPGCTYKYLN TRLFTVPWPV KGCTVKYTEA EIAAACQTFL KLNDYLQVET IQALEELAVR EKANEDAVPL CMAEFPRAGV GPSCDDEVDL KSRAAYNVTL LNFMDPQKMP YLKEEPYFGM GKMAVSWHHD ENLVDRSAVA VYSYSCEGSE DESEDESSFE GRDPDTWHVG FKISWDIETP GLTIPLHQGD CYFMLDDLNA THQHCVLAGS QPRFSSTHRV AECSTGTLDY ILERCQLALQ NVLNDSDDGD VSLKSFDPAV LKQGEEIHNE VEFEWLRQFW FQGNRYKLCT DWWCEPMTHL EGLWKKMESM TNAVLREVKR EGLPVEQRSE ILSAILVPLT VRQNLRKEWH ARCQSRVVRT LPVQQKPDCR PYWEKDDPSM PLPFDLTDVV SELRGQLLEA RS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.