Details for: Grk6

Gene ID: 26385

Symbol: Grk6

Ensembl ID: ENSMUSG00000074886

Description: G protein-coupled receptor kinase 6

Associated with

Other Information

Genular Protein ID: 4102705866

Symbol: GRK6_MOUSE

Name: G protein-coupled receptor kinase 6

UniProtKB Accession Codes:

O70293 O70294 O70295 Q6DI67

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 9 ChiTaRS 1 DNASU 1 EC 2 EMBL 9 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 3 GeneTree 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MGI 1 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 5 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 6 Rhea 3 SMART 3 SMR 1 STRING 1 SUPFAM 2 SwissPalm 1 TreeFam 1 UCSC 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 10506199

Title: The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation.

PubMed ID: 10506199

DOI: 10.1074/jbc.274.41.29381

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12032308

Title: Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

PubMed ID: 12032308

DOI: 10.1073/pnas.112198299

PubMed ID: 14634128

Title: Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6.

PubMed ID: 14634128

DOI: 10.4049/jimmunol.171.11.6128

PubMed ID: 12718862

Title: Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice.

PubMed ID: 12718862

DOI: 10.1016/s0896-6273(03)00192-2

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 576
  • Mass: 65979
  • Checksum: 91EEC2028CAF4B91
  • Sequence:
    • MELENIVANT VLLKAREGGG GNRKGKSKKW RQMLQFPHIS QCEELRLSLE RDYHSLCERQ 
PIGRLLFREF CATRPELTRC TAFLDGVSEY EVTPDEKRKA CGRRLMQNFL SHTGPDLIPE 
VPRQLVSNCA QRLEQGPCKD LFQELTRLTH EYLSTAPFAD YLDSIYFNRF LQWKWLERQP 
VTKNTFRQYR VLGKGGFGEV CACQVRATGK MYACKKLEKK RIKKRKGEAM ALNEKQILEK 
VNSRFVVSLA YAYETKDALC LVLTLMNGGD LKFHIYHMGQ AGFPEARAVF YAAEICCGLE 
DLHRERIVYR DLKPENILLD DHGHIRISDL GLAVHVPEGQ TIKGRVGTVG YMAPEVVRNE 
RYTFSPDWWA LGCLLYEMIA GQSPFQQRKK KIKREEVERL VKEVAEEYTD RFSSQARSLC 
SQLLSKDPAE RLGCRGGGAR EVKEHPLFKK LNFKRLGAGM LEPPFKPDPQ AIYCKDVLDI 
EQFSTVKGVD LEPTDQDFYQ KFATGSVSIP WQNEMVETEC FQELNVFGLD GSVPPDLDWK 
GQPTAPPKKG LLQRLFSRQD CCGNCSDSEE ELPTRL

Genular Protein ID: 3103723489

Symbol: A0A286YE10_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A286YE10

Database IDs:

AGR 1 ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 4 GeneTree 1 InterPro 9 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 8 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SMART 3 SMR 1 SUPFAM 2 VEuPathDB 1 jPOST 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 542
  • Mass: 62180
  • Checksum: 34D38176CF693F09
  • Sequence:
    • MELENIVANT VLLKAREGGG GNRKGKSKKW RQMLQFPHIS QCEELRLSLE RDYHSLCERQ 
PIGRLLFREF CATRPELTRC TAFLDGVSEY EVTPDEKRKA CGRRLMQNFL SHTGPDLIPE 
VPRQLVSNCA QRLEQGPCKD LFQELTRLTH EYLSTAPFAD YLDSIYFNRF LQWKWLERQP 
VTKNTFRQYR VLGKGGFGEV CACQVRATGK MYACKKLEKK RIKKRKGEAM ALNEKQILEK 
VNSRFVAGFP EARAVFYAAE ICCGLEDLHR ERIVYRDLKP ENILLDDHGH IRISDLGLAV 
HVPEGQTIKG RVGTVGYMAP EVVRNERYTF SPDWWALGCL LYEMIAGQSP FQQRKKKIKR 
EEVERLVKEV AEEYTDRFSS QARSLCSQLL SKDPAERLGC RGGGAREVKE HPLFKKLNFK 
RLGAGMLEPP FKPDPQAIYC KDVLDIEQFS TVKGVDLEPT DQDFYQKFAT GSVSIPWQNE 
MVETECFQEL NVFGLDGSVP PDLDWKGQPT APPKKGLLQR LFSRQDCCGN CSDSEEELPT 
RL

Genular Protein ID: 895498213

Symbol: A0A286YDZ5_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A286YDZ5

Database IDs:

AGR 1 ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 3 GeneTree 1 InterPro 9 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 8 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SAM 1 SMART 3 SMR 1 SUPFAM 2 VEuPathDB 1 jPOST 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 557
  • Mass: 63564
  • Checksum: A7566BA775FA543E
  • Sequence:
    • MLQFPHISQC EELRLSLERD YHSLCERQPI GRLLFREFCA TRPELTRCTA FLDGVSEYEV 
TPDEKRKACG RRLMQNFLSH TGPDLIPEVP RQLVSNCAQR LEQGPCKDLF QELTRLTHEY 
LSTAPFADYL DSIYFNRFLQ WKWLERQPVT KNTFRQYRVL GKGGFGEVCA CQVRATGKMY 
ACKKLEKKRI KKRKGEAMAL NEKQILEKVN SRFVVSLAYA YETKDALCLV LTLMNGGDLK 
FHIYHMGQAG FPEARAVFYA AEICCGLEDL HRERIVYRDL KPENILLDDH GHIRISDLGL 
AVHVPEGQTI KGRVGTVGYM APEVVRNERY TFSPDWWALG CLLYEMIAGQ SPFQQRKKKI 
KREEVERLVK EVAEEYTDRF SSQARSLCSQ LLSKDPAERL GCRGGGAREV KEHPLFKKLN 
FKRLGAGMLE PPFKPDPQAI YCKDVLDIEQ FSTVKGVDLE PTDQDFYQKF ATGSVSIPWQ 
NEMVETECFQ ELNVFGLDGS VPPDLDWKGQ PTAPPKKGLL QRLFSRQRIA VGTAATVRKS 
SPPASSPQAE APTGGWR

Genular Protein ID: 2645056006

Symbol: Q9EP84_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9EP84

Database IDs:

AGR 1 ARBA 6 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 2 GO 3 Gene3D 3 GeneTree 1 HOGENOM 1 InterPro 9 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 8 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 2 RuleBase 1 SAM 1 SMART 3 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10486211

Title: Alternative splicing produces transcripts encoding four variants of mouse G-protein-coupled receptor kinase 6.

PubMed ID: 10486211

DOI: 10.1006/geno.1999.5901

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 560
  • Mass: 64282
  • Checksum: 8A67E11BA414E7D9
  • Sequence:
    • MELENIVANT VLLKAREGGG GNRKGKSKKW RQMLQFPHIS QCEELRLSLE RDYHSLCERQ 
PIGRLLFREF CATRPELTRC TAFLDGVSEY EVTPDEKRKA CGRRLMQNFL SHTGPDLIPE 
VPRQLVSNCA QRLEQGPCKD LFQELTRLTH EYLSTAPFAD YLDSIYFNRF LQWKWLERQP 
VTKNTFRQYR VLGKGGFGEV CACQVRATGK MYACKKLEKK RIKKRKGEAM ALNEKQILEK 
VNSRFVVSLA YAYETKDALC LVLTLMNGGD LKFHIYHMGQ AGFPEARAVF YAAEICCGLE 
DLHRERIVYR DLKPENILLD DHGHIRISDL GLAVHVPEGQ TIKGRVGTVG YMAPEVVRNE 
RYTFSPDWWA LGCLLYEMIA GQSPFQQRKK KIKREEVERL VKEVAEEYTD RFSSQARSLC 
SQLLSKDPAE RLGCRGGGAR EVKEHPLFKK LNFKRLGAGM LEPPFKPDPQ AIYCKDVLDI 
EQFSTVKGVD LEPTDQDFYQ KFATGSVSIP WQNEMVETEC FQELNVFGLD GSVPPDLDWK 
GQPTAPPKKG LLQRLFSRQR

Genular Protein ID: 306180597

Symbol: A0A286YDA5_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A286YDA5

Database IDs:

AGR 1 ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 3 GeneTree 1 InterPro 9 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 8 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SAM 1 SMART 3 SMR 1 SUPFAM 2 VEuPathDB 1 jPOST 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 584
  • Mass: 66611
  • Checksum: 61C373F92A5A4968
  • Sequence:
    • MELENIVANT VLLKAREGGG GNRKGKSKKW RQMLQFPHIS QCEELRLSLE RDYHSLCERQ 
PIGRLLFREF CATRPELTRC TAFLDGVSEY EVTPDEKRKA CGRRLMQNFL SHTGPDLIPE 
VPRQLVSNCA QRLEQGPCKD LFQELTRLTH EYLSTAPFAD YLDSIYFNRF LQWKWLERQP 
VTKNTFRQYR VLGKGGFGEV RATGKMYACK KLEKKRIKKR KGEAMALNEK QILEKVNSRF 
VVSLAYAYET KDALCLVLTL MNGGDLKFHI YHMGQAGFPE ARAVFYAAEI CCGLEDLHRE 
RIVYRDLKPE NILLDDHGHI RISDLGLAVH VPEGQTIKGR VGTVGYMAPE VVRNERYTFS 
PDWWALGCLL YEMIAGQSPF QQRKKKIKRE EVERLVKEVA EEYTDRFSSQ ARSLCSQLLS 
KDPAERLGCR GGGAREVKEH PLFKKLNFKR LGAGMLEPPF KPDPQAIYCK DVLDIEQFST 
VKGVDLEPTD QDFYQKFATG SVSIPWQNEM VETECFQELN VFGLDGSVPP DLDWKGQPTA 
PPKKGLLQRL FSRQRIAVGT AATVRKSSPP ASSPQAEAPT GGWR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.