Details for: Hsf4

Gene ID: 26386

Symbol: Hsf4

Ensembl ID: ENSMUSG00000033249

Description: heat shock transcription factor 4

Associated with

  • Chromatin
    (GO:0000785)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Identical protein binding
    (GO:0042802)
  • Lens fiber cell differentiation
    (GO:0070306)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nuclear speck
    (GO:0016607)
  • Nucleus
    (GO:0005634)
  • Protein phosphatase binding
    (GO:0019903)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)

Other Information

Genular Protein ID: 2627089674

Symbol: HSF4_MOUSE

Name: Heat shock factor protein 4

UniProtKB Accession Codes:

Q9R0L1 Q9R0L2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 2 CTD 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 12 Gene3D 1 GeneTree 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10488131

Title: The mammalian HSF4 gene generates both an activator and a repressor of heat shock genes by alternative splicing.

PubMed ID: 10488131

DOI: 10.1074/jbc.274.39.27845

PubMed ID: 16581800

Title: Association and regulation of heat shock transcription factor 4b with both extracellular signal-regulated kinase mitogen-activated protein kinase and dual-specificity tyrosine phosphatase DUSP26.

PubMed ID: 16581800

DOI: 10.1128/mcb.26.8.3282-3294.2006

PubMed ID: 31786107

Title: Heat shock factor 4 regulates lysosome activity by modulating the alphaB-crystallin-ATP6V1A-mTOR complex in ocular lens.

PubMed ID: 31786107

DOI: 10.1016/j.bbagen.2019.129496

Sequence Information:

  • Length: 492
  • Mass: 53255
  • Checksum: 952AB78255AD3CA0
  • Sequence:
    • MQEAPAALPT EPGPSPVPAF LGKLWALVGD PGTDHLIRWS PSGTSFLVSD QSRFAKEVLP 
QYFKHSNMAS FVRQLNMYGF RKVVSIEQGG LLRPERDHVE FQHPSFVRGR EQLLERVRRK 
VPALRGDDSR WRPEDLSRLL GEVQALRGVQ ESTEARLQEL RQQNEILWRE VVTLRQSHSQ 
QHRVIGKLIQ CLFGPLQTGP SSTGAKRKLS LMLDEGSACS ASAKFNACPV SGALLQDPYF 
IQSPLPETTL GLSPHRARGP IISDIPEDSP SPEGHRLSPS GGCRRVKGLA LLKEEPASPG 
GDGEAGLALA PNECDFCVTA PPPLPVAVVQ AILEGKGSYS PEGPRSVQQP EPRGPREVPD 
RGTLGLDRGN RSPESLLPPM LLRPAPETLE PVAPVDVLGP SLHGREWTLM DLDMELSLMQ 
PLAPETDEAE LTVKELNSSG VGKDHTLGTP LMLDVQADLE GAALSVPGAL TLYNVTESNA 
SYLDPGASPS SP

Genular Protein ID: 2013484340

Symbol: Q3UG93_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UG93

Database IDs:

AGR 1 ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 Ensembl 2 GO 4 Gene3D 1 GeneTree 1 InterPro 2 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 432
  • Mass: 46714
  • Checksum: 76175F6C889C071F
  • Sequence:
    • MGAGRRPRHR PPHPLEPDGF RKVVSIEQGG LLRPERDHVE FQHPSFVRGR EQLLERVRRK 
VPALRGDDSR WRPEDLSRLL GEVQALRGVQ ESTEARLQEL RQQNEILWRE VVTLRQSHSQ 
QHRVIGKLIQ CLFGPLQTGP SSTGAKRKLS LMLDEGSACS ASAKFNACPV SGALLQDPYF 
IQSPLPETTL GLSPHRARGP IISDIPEDSP SPEGHRLSPS GGCRRVKGLA LLKEEPASPG 
GDGEAGLALA PNECDFCVTA PPPLPVAVVQ AILEGKGSYS PEGPRSVQQP EPRGPREVPD 
RGTLGLDRGN RSPESLLPPM LLRPAPETLE PVAPVDVLGP SLHGREWTLM DLDMELSLMQ 
PLAPETDEAE LTVKELNSSG VGKDHTLGTP LMLDVQADLE GAALSVPGAL TLYNVTESNA 
SYLDPGASPS SP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.