Details for: Ifi202b

Gene ID: 26388

Symbol: Ifi202b

Ensembl ID: ENSMUSG00000026535

Description: interferon activated gene 202B

Associated with

  • Cellular response to interferon-beta
    (GO:0035458)

Other Information

Genular Protein ID: 3297494095

Symbol: IFI2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2477366

Title: Interferons as gene activators. Indications for repeated gene duplication during the evolution of a cluster of interferon-activatable genes on murine chromosome 1.

PubMed ID: 2477366

DOI: 10.1016/s0021-9258(18)71476-2

PubMed ID: 10493828

Title: Characteristics of three homologous 202 genes (Ifi202a, ifi202b, and ifi202c) from the murine interferon-activatable gene 200 cluster.

PubMed ID: 10493828

DOI: 10.1006/geno.1999.5923

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8454910

Title: Interferon action: cytoplasmic and nuclear localization of the interferon-inducible 52-kD protein that is encoded by the Ifi 200 gene from the gene 200 cluster.

PubMed ID: 8454910

DOI: 10.1089/jir.1993.13.43

PubMed ID: 8910340

Title: p202, an interferon-inducible modulator of transcription, inhibits transcriptional activation by the p53 tumor suppressor protein, and a segment from the p53-binding protein 1 that binds to p202 overcomes this inhibition.

PubMed ID: 8910340

DOI: 10.1074/jbc.271.44.27544

PubMed ID: 8524315

Title: The interferon-inducible p202 protein as a modulator of transcription: inhibition of NF-kappa B, c-Fos, and c-Jun activities.

PubMed ID: 8524315

DOI: 10.1128/mcb.16.1.359

PubMed ID: 9821952

Title: p202 self-associates through a sequence conserved among the members of the 200-family proteins.

PubMed ID: 9821952

DOI: 10.1016/s0014-5793(98)01263-0

PubMed ID: 11567633

Title: Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus.

PubMed ID: 11567633

DOI: 10.1016/s1074-7613(01)00196-0

PubMed ID: 14764608

Title: Interleukin-6 induces expression of Ifi202, an interferon-inducible candidate gene for lupus susceptibility.

PubMed ID: 14764608

DOI: 10.1074/jbc.m313140200

PubMed ID: 16670293

Title: Increased expression of Ifi202, an IFN-activatable gene, in B6.Nba2 lupus susceptible mice inhibits p53-mediated apoptosis.

PubMed ID: 16670293

DOI: 10.4049/jimmunol.176.10.5863

PubMed ID: 19131592

Title: HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA.

PubMed ID: 19131592

DOI: 10.1126/science.1169841

PubMed ID: 23850291

Title: Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation.

PubMed ID: 23850291

DOI: 10.1016/j.celrep.2013.06.024

PubMed ID: 23567559

Title: Structural basis for termination of AIM2-mediated signaling by p202.

PubMed ID: 23567559

DOI: 10.1038/cr.2013.52

PubMed ID: 24419611

Title: Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling.

PubMed ID: 24419611

DOI: 10.1107/s2053230x1303135x

Sequence Information:

  • Length: 445
  • Mass: 50466
  • Checksum: 5EA0E93E143C58EA
  • Sequence:
  • MSNRNLRSST NSEFSEGQHQ TPSSDSSGHG EDQPQASPGP NKKSHTPKKN ISKGAVLHEK 
    PMTVMVLTAT EPFNYKEGKE NMFHATVATE SQYYRVKVFN MDLKEKFTEN KFITISKYFN 
    SSGILEINET ATVSEAAPNQ IIEVPKNIIR SAKETLKISK IKELDSGTLI YGVFAVEKKK 
    VNDKSITFKI KDNEDNIKVV WDKKQHNINY EKGDKLQLFS FHLRKGNGKP ILHSGNHSFI 
    KGEKLLKESF EGDGYHKGPK QVVALKATKL FTYDSIKSKK MFHATVATDT EFFRVMVFEE 
    NLEKKFIPGN TIALSDYFGM YGSLAIHEYS SVSEVKSQNK EDSSSSDERL IEHLKICDLH 
    LQTKERLVDG EFKVYRKSTG NNCICYGIWD DTGAMKVVVS GQLTSVNCEI GNTIRLVCFE 
    LTSNADEWFL RSTRYSYMEV IMPEK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.