Map3k3 | ENSMUSG00000020700 | NCBI 26406

Details for: Map3k3

Gene ID: 26406

Symbol: Map3k3

Ensembl ID: ENSMUSG00000020700

Description: mitogen-activated protein kinase kinase kinase 3

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Interleukin-1 family signaling
(R-MMU-446652)
Interleukin-1 signaling
(R-MMU-9020702)
Signaling by interleukins
(R-MMU-449147)
Atp binding
(GO:0005524)
Blood vessel development
(GO:0001568)
Cytoplasm
(GO:0005737)
Intracellular signal transduction
(GO:0035556)
Mapk cascade
(GO:0000165)
Map kinase kinase kinase activity
(GO:0004709)
Metal ion binding
(GO:0046872)
Negative regulation of cellular senescence
(GO:2000773)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of cell migration involved in sprouting angiogenesis
(GO:0090050)
Positive regulation of cell proliferation in bone marrow
(GO:0071864)
Positive regulation of p38mapk cascade
(GO:1900745)
Protein autophosphorylation
(GO:0046777)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein serine/threonine kinase activity
(GO:0004674)
Protein serine kinase activity
(GO:0106310)

Other Information

Proteins

Mitogen-activated protein kinase kinase kinase 3

Genular Protein ID: 1790354462

Symbol: M3K3_MOUSE

Name: Mitogen-activated protein kinase kinase kinase 3

UniProtKB Accession Codes:

Q61084

Database IDs:

Citations:

PubMed ID: 8621389

Title: Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase.

PubMed ID: 8621389

DOI: 10.1074/jbc.271.10.5361

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12391307

Title: JLP: a scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors.

PubMed ID: 12391307

DOI: 10.1073/pnas.232310199

PubMed ID: 14634666

Title: Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock.

PubMed ID: 14634666

DOI: 10.1038/ncb1071

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 626
Mass: 70776
Checksum: 00EF2442C9E56E0B
Sequence:

MDEQEALDSI MKDLVALQMS RRTRLSGYET MKNKDTGHPN RQSDVRIKFE HNGERRIIAF 
SRPVRYEDVE HKVTTVFGQP LDLHYMNNEL SILLKNQDDL DKAIDILDRS SSMKSLRILL 
LSQDRNHTSS SPHSGVSRQV RIKPSQSAGD INTIYQAPEP RSRHLSVSSQ NPGRSSPPPG 
YVPERQQHIA RQGSYTSINS EGEFIPETSE QCMLDPLSSA ENSLSGSCQS LDRSADSPSF 
RKSQMSRARS FPDNRKECSD RETQLYDKGV KGGTYPRRYH VSVHHKDYND GRRTFPRIRR 
HQGNLFTLVP SSRSLSTNGE NMGVAVQYLD PRGRLRSADS ENALTVQERN VPTKSPSAPI 
NWRRGKLLGQ GAFGRVYLCY DVDTGRELAS KQVQFDPDSP ETSKEVSALE CEIQLLKNLQ 
HERIVQYYGC LRDRAEKILT IFMEYMPGGS VKDQLKAYGA LTESVTRKYT RQILEGMSYL 
HSNMIVHRDI KGANILRDSA GNVKLGDFGA SKRLQTICMS GTGIRSVTGT PYWMSPEVIS 
GEGYGRKADV WSLGCTVVEM LTEKPPWAEY EAMAAIFKIA TQPTNPQLPS HISEHGRDFL 
RRIFVEARQR PSAEELLTHH FAQLVY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Map3k3

Associated with

Other Information

Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase. PubMed ID: 8621389

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

JLP: a scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors. PubMed ID: 12391307

Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock. PubMed ID: 14634666

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355