Details for: Map3k7
Associated with
Other Information
Genular Protein ID: 2365032106
Symbol: M3K7_MOUSE
Name: Mitogen-activated protein kinase kinase kinase 7
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8533096
Title: Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction.
PubMed ID: 8533096
PubMed ID: 10748100
Title: BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6.
PubMed ID: 10748100
PubMed ID: 12556533
Title: Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon).
PubMed ID: 12556533
PubMed ID: 16157589
Title: X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase 1 (JNK1) activation by transforming growth factor beta1 (TGF-beta1) through ubiquitin-mediated proteosomal degradation of the TGF-beta1-activated kinase 1 (TAK1).
PubMed ID: 16157589
PubMed ID: 17548520
Title: Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses.
PubMed ID: 17548520
DOI: 10.1084/jem.20062694
PubMed ID: 17709393
Title: Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1.
PubMed ID: 17709393
DOI: 10.1128/mcb.00025-07
PubMed ID: 17496917
Title: Ubiquitin-mediated activation of TAK1 and IKK.
PubMed ID: 17496917
PubMed ID: 17242355
Title: Large-scale phosphorylation analysis of mouse liver.
PubMed ID: 17242355
PubMed ID: 17965022
Title: TAK1 is a central mediator of NOD2 signaling in epidermal cells.
PubMed ID: 17965022
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 20060931
PubMed ID: 25632008
Title: Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7.
PubMed ID: 25632008
PubMed ID: 27084103
Title: POSH regulates CD4+ T cell differentiation and survival.
PubMed ID: 27084103
PubMed ID: 27777970
Title: PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.
PubMed ID: 27777970
PubMed ID: 28842570
Title: Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.
PubMed ID: 28842570
PubMed ID: 29291351
Title: The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.
PubMed ID: 29291351
DOI: 10.1038/nm.4461
PubMed ID: 31519887
Title: K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation.
PubMed ID: 31519887
PubMed ID: 37832545
Title: TAK1 is an essential kinase for STING trafficking.
PubMed ID: 37832545
Sequence Information:
- Length: 579
- Mass: 64228
- Checksum: 97C8F6F3C8E283EE
- Sequence:
MSTASAASSS SSSSASEMIE APSQVLNFEE IDYKEIEVEE VVGRGAFGVV CKAKWRAKDV AIKQIESESE RKAFIVELRQ LSRVNHPNIV KLYGACLNPV CLVMEYAEGG SLYNVLHGAE PLPYYTAAHA MSWCLQCSQG VAYLHSMQPK ALIHRDLKPP NLLLVAGGTV LKICDFGTAC DIQTHMTNNK GSAAWMAPEV FEGSNYSEKC DVFSWGIILW EVITRRKPFD EIGGPAFRIM WAVHNGTRPP LIKNLPKPIE SLMTRCWSKD PSQRPSMEEI VKIMTHLMRY FPGADEPLQY PCQYSDEGQS NSATSTGSFM DIASTNTSNK SDTNMEQVPA TNDTIKRLES KLLKNQAKQQ SESGRLSLGA SRGSSVESLP PTSEGKRMSA DMSEIEARIV ATAGNGQPRR RSIQDLTVTG TEPGQVSSRS SSPSVRMITT SGPTSEKPAR SHPWTPDDST DTNGSDNSIP MAYLTLDHQL QPLAPCPNSK ESMAVFEQHC KMAQEYMKVQ TEIALLLQRK QELVAELDQD EKDQQNTSRL VQEHKKLLDE NKSLSTYYQQ CKKQLEVIRS QQQKRQGTS
Genular Protein ID: 1929777681
Symbol: Q923A8_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17242355
Title: Large-scale phosphorylation analysis of mouse liver.
PubMed ID: 17242355
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 21750661
Title: Modernizing reference genome assemblies.
PubMed ID: 21750661
Sequence Information:
- Length: 606
- Mass: 67194
- Checksum: AB8664F389272102
- Sequence:
MSTASAASSS SSSSASEMIE APSQVLNFEE IDYKEIEVEE VVGRGAFGVV CKAKWRAKDV AIKQIESESE RKAFIVELRQ LSRVNHPNIV KLYGACLNPV CLVMEYAEGG SLYNVLHGAE PLPYYTAAHA MSWCLQCSQG VAYLHSMQPK ALIHRDLKPP NLLLVAGGTV LKICDFGTAC DIQTHMTNNK GSAAWMAPEV FEGSNYSEKC DVFSWGIILW EVITRRKPFD EIGGPAFRIM WAVHNGTRPP LIKNLPKPIE SLMTRCWSKD PSQRPSMEEI VKIMTHLMRY FPGADEPLQY PCQYSDEGQS NSATSTGSFM DIASTNTSNK SDTNMEQVPA TNDTIKRLES KLLKNQAKQQ SESGRLSLGA SRGSSVESLP PTSEGKRMSA DMSEIEARIV ATAAYSKPKR GHRKTASFGN ILDVPEIVIS GNGQPRRRSI QDLTVTGTEP GQVSSRSSSP SVRMITTSGP TSEKPARSHP WTPDDSTDTN GSDNSIPMAY LTLDHQLQPL APCPNSKESM AVFEQHCKMA QEYMKVQTEI ALLLQRKQEL VAELDQDEKD QQNTSRLVQE HKKLLDENKS LSTYYQQCKK QLEVIRSQQQ KRQGTS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.