Details for: Mapk14

Gene ID: 26416

Symbol: Mapk14

Ensembl ID: ENSMUSG00000053436

Description: mitogen-activated protein kinase 14

Associated with

Other Information

Genular Protein ID: 3130554158

Symbol: MK14_MOUSE

Name: CRK1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7914033

Title: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells.

PubMed ID: 7914033

DOI: 10.1126/science.7914033

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8444355

Title: Novel CDC2-related protein kinases produced in murine hematopoietic stem cells.

PubMed ID: 8444355

DOI: 10.1016/0378-1119(93)90411-u

PubMed ID: 7839144

Title: Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms.

PubMed ID: 7839144

DOI: 10.1126/science.7839144

PubMed ID: 10601328

Title: A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase.

PubMed ID: 10601328

DOI: 10.1083/jcb.147.6.1129

PubMed ID: 10704466

Title: Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells.

PubMed ID: 10704466

DOI: 10.1084/jem.191.5.859

PubMed ID: 10943842

Title: Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis.

PubMed ID: 10943842

DOI: 10.1016/s0092-8674(00)00027-1

PubMed ID: 11909979

Title: MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts.

PubMed ID: 11909979

DOI: 10.1128/mcb.22.8.2871-2881.2002

PubMed ID: 12391307

Title: JLP: a scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors.

PubMed ID: 12391307

DOI: 10.1073/pnas.232310199

PubMed ID: 16288922

Title: New insights into the catalytic activation of the MAPK phosphatase PAC-1 induced by its substrate MAPK ERK2 binding.

PubMed ID: 16288922

DOI: 10.1016/j.jmb.2005.10.006

PubMed ID: 15735649

Title: The autoimmune suppressor Gadd45alpha inhibits the T cell alternative p38 activation pathway.

PubMed ID: 15735649

DOI: 10.1038/ni1176

PubMed ID: 16751104

Title: p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.

PubMed ID: 16751104

DOI: 10.1016/j.cell.2006.03.048

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

DOI: 10.4049/jimmunol.179.9.5864

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 18669639

Title: Enzymatic activity and substrate specificity of mitogen-activated protein kinase p38alpha in different phosphorylation states.

PubMed ID: 18669639

DOI: 10.1074/jbc.m801703200

PubMed ID: 12452429

Title: In the cellular garden of forking paths: how p38 MAPKs signal for downstream assistance.

PubMed ID: 12452429

DOI: 10.1515/bc.2002.173

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 20626350

Title: Mechanisms and functions of p38 MAPK signalling.

PubMed ID: 20626350

DOI: 10.1042/bj20100323

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 9122194

Title: The structure of mitogen-activated protein kinase p38 at 2.1-A resolution.

PubMed ID: 9122194

DOI: 10.1073/pnas.94.6.2327

PubMed ID: 12086621

Title: Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b.

PubMed ID: 12086621

DOI: 10.1016/s1097-2765(02)00525-7

PubMed ID: 15837310

Title: The development of monocyclic pyrazolone based cytokine synthesis inhibitors.

PubMed ID: 15837310

DOI: 10.1016/j.bmcl.2005.03.007

PubMed ID: 15837333

Title: The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-alpha) production.

PubMed ID: 15837333

DOI: 10.1016/j.bmcl.2005.02.066

PubMed ID: 17395714

Title: Molecular basis of MAPK-activated protein kinase 2:p38 assembly.

PubMed ID: 17395714

DOI: 10.1073/pnas.0701679104

PubMed ID: 22375048

Title: A distinct interaction mode revealed by the crystal structure of the kinase p38alpha with the MAPK binding domain of the phosphatase MKP5.

PubMed ID: 22375048

DOI: 10.1126/scisignal.2002241

Sequence Information:

  • Length: 360
  • Mass: 41287
  • Checksum: DFB03EBCE97BB51A
  • Sequence:
  • MSQERPTFYR QELNKTIWEV PERYQNLSPV GSGAYGSVCA AFDTKTGHRV AVKKLSRPFQ 
    SIIHAKRTYR ELRLLKHMKH ENVIGLLDVF TPARSLEEFN DVYLVTHLMG ADLNNIVKCQ 
    KLTDDHVQFL IYQILRGLKY IHSADIIHRD LKPSNLAVNE DCELKILDFG LARHTDDEMT 
    GYVATRWYRA PEIMLNWMHY NQTVDIWSVG CIMAELLTGR TLFPGTDHID QLKLILRLVG 
    TPGAELLKKI SSESARNYIQ SLAQMPKMNF ANVFIGANPL AVDLLEKMLV LDSDKRITAA 
    QALAHAYFAQ YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES

Genular Protein ID: 1530573165

Symbol: Q5U421_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 360
  • Mass: 41487
  • Checksum: F1F20352F76590BD
  • Sequence:
  • MSQERPTFYR QELNKTIWEV PERYQNLSPV GSGAYGSVCA AFDTKTGHRV AVKKLSRPFQ 
    SIIHAKRTYR ELRLLKHMKH ENVIGLLDVF TPARSLEEFN DVYLVTHLMG ADLNNIVKCQ 
    KLTDDHVQFL IYQILRGLKY IHSADIIHRD LKPSNLAVNE DCELKILDFG LARHTDDEMT 
    GYVATRWYRA PEIMLNWMHY NQTVDIWSVG CIMAELLTGR TLFPGTDHIN QLQQIMRLTG 
    TPPAYLINRM PSHEARNYIQ SLAQMPKMNF ANVFIGANPL AVDLLEKMLV LDSDKRITAA 
    QALAHAYFAQ YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.