Mapk9 | ENSMUSG00000020366 | NCBI 26420

Details for: Mapk9

Gene ID: 26420

Symbol: Mapk9

Ensembl ID: ENSMUSG00000020366

Description: mitogen-activated protein kinase 9

Associated with

Activation of the ap-1 family of transcription factors
(R-MMU-450341)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular senescence
(R-MMU-2559583)
Cytokine signaling in immune system
(R-MMU-1280215)
Fc epsilon receptor (fceri) signaling
(R-MMU-2454202)
Fceri mediated mapk activation
(R-MMU-2871796)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Interleukin-17 signaling
(R-MMU-448424)
Jnk (c-jun kinases) phosphorylation and activation mediated by activated human tak1
(R-MMU-450321)
Map kinase activation
(R-MMU-450294)
Mapk targets/ nuclear events mediated by map kinases
(R-MMU-450282)
Myd88 cascade initiated on plasma membrane
(R-MMU-975871)
Myd88 dependent cascade initiated on endosome
(R-MMU-975155)
Myd88-independent tlr4 cascade
(R-MMU-166166)
Myd88:mal(tirap) cascade initiated on plasma membrane
(R-MMU-166058)
Oxidative stress induced senescence
(R-MMU-2559580)
Signaling by interleukins
(R-MMU-449147)
Toll-like receptor cascades
(R-MMU-168898)
Toll like receptor 2 (tlr2) cascade
(R-MMU-181438)
Toll like receptor 3 (tlr3) cascade
(R-MMU-168164)
Toll like receptor 4 (tlr4) cascade
(R-MMU-166016)
Toll like receptor 5 (tlr5) cascade
(R-MMU-168176)
Toll like receptor 7/8 (tlr7/8) cascade
(R-MMU-168181)
Toll like receptor 9 (tlr9) cascade
(R-MMU-168138)
Toll like receptor 10 (tlr10) cascade
(R-MMU-168142)
Toll like receptor tlr1:tlr2 cascade
(R-MMU-168179)
Toll like receptor tlr6:tlr2 cascade
(R-MMU-168188)
Traf6 mediated induction of nfkb and map kinases upon tlr7/8 or 9 activation
(R-MMU-975138)
Trif (ticam1)-mediated tlr4 signaling
(R-MMU-937061)
Apoptotic signaling pathway
(GO:0097190)
Atp binding
(GO:0005524)
Cellular response to cadmium ion
(GO:0071276)
Cellular response to reactive oxygen species
(GO:0034614)
Cellular response to uv
(GO:0034644)
Cysteine-type endopeptidase activator activity involved in apoptotic process
(GO:0008656)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Inflammatory response to wounding
(GO:0090594)
Jnk cascade
(GO:0007254)
Jun kinase activity
(GO:0004705)
Mitochondrion
(GO:0005739)
Mitogen-activated protein kinase kinase kinase binding
(GO:0031435)
Modulation of chemical synaptic transmission
(GO:0050804)
Neuron projection development
(GO:0031175)
Nuclear speck
(GO:0016607)
Nucleus
(GO:0005634)
Perikaryon
(GO:0043204)
Plasma membrane
(GO:0005886)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of apoptotic signaling pathway
(GO:2001235)
Positive regulation of cell differentiation
(GO:0045597)
Positive regulation of chemokine production
(GO:0032722)
Positive regulation of cytokine production involved in inflammatory response
(GO:1900017)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of macrophage derived foam cell differentiation
(GO:0010744)
Positive regulation of nitric-oxide synthase biosynthetic process
(GO:0051770)
Positive regulation of nitric oxide biosynthetic process
(GO:0045429)
Positive regulation of podosome assembly
(GO:0071803)
Positive regulation of prostaglandin biosynthetic process
(GO:0031394)
Positive regulation of prostaglandin secretion
(GO:0032308)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032436)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of protein ubiquitination
(GO:0031398)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein localization to tricellular tight junction
(GO:0061833)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine/tyrosine kinase activity
(GO:0004712)
Protein serine/threonine kinase activity
(GO:0004674)
Protein serine kinase activity
(GO:0106310)
Regulation of circadian rhythm
(GO:0042752)
Regulation of jnk cascade
(GO:0046328)
Regulation of protein ubiquitination
(GO:0031396)
Release of cytochrome c from mitochondria
(GO:0001836)
Response to cadmium ion
(GO:0046686)
Response to xenobiotic stimulus
(GO:0009410)
Rhythmic process
(GO:0048511)
Schaffer collateral - ca1 synapse
(GO:0098685)

Other Information

Proteins

Genular Protein ID: 2745238629

Symbol: MK09_MOUSE

Name: Mitogen-activated protein kinase 9

UniProtKB Accession Codes:

Q9WTU6 Q5NCK9 Q5NCL5 Q8C097 Q8VDD2 Q9WTU4 Q9WTU5

Database IDs:

Citations:

PubMed ID: 9806643

Title: Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

PubMed ID: 9806643

DOI: 10.1016/s1074-7613(00)80640-8

PubMed ID: 10523642

Title: JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a scaffold factor in the JNK signaling pathway.

PubMed ID: 10523642

DOI: 10.1128/mcb.19.11.7539

PubMed ID: 10674476

Title: Analysis of splicing of four mouse JNK/SAPKalpha variants.

PubMed ID: 10674476

DOI: 10.1097/00001756-200002070-00017

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10811224

Title: JNK is required for effector T-cell function but not for T-cell activation.

PubMed ID: 10811224

DOI: 10.1038/35011091

PubMed ID: 11562351

Title: Requirement of the JIP1 scaffold protein for stress-induced JNK activation.

PubMed ID: 11562351

DOI: 10.1101/gad.922801

PubMed ID: 16628014

Title: Common and divergent roles for members of the mouse DCX superfamily.

PubMed ID: 16628014

DOI: 10.4161/cc.5.9.2715

PubMed ID: 16973441

Title: JNK2 is a positive regulator of the cJun transcription factor.

PubMed ID: 16973441

DOI: 10.1016/j.molcel.2006.07.028

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21554942

Title: Activity of all JNK isoforms contributes to neurite growth in spiral ganglion neurons.

PubMed ID: 21554942

DOI: 10.1016/j.heares.2011.04.011

PubMed ID: 22441692

Title: JNK regulates the photic response of the mammalian circadian clock.

PubMed ID: 22441692

DOI: 10.1038/embor.2012.37

PubMed ID: 27084103

Title: POSH regulates CD4+ T cell differentiation and survival.

PubMed ID: 27084103

DOI: 10.4049/jimmunol.1501728

PubMed ID: 29153991

Title: Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells.

PubMed ID: 29153991

DOI: 10.1016/j.stemcr.2017.10.017

Sequence Information:

Length: 423
Mass: 48189
Checksum: 0E759B486ABCE20D
Sequence:

MSDSKSDGQF YSVQVADSTF TVLKRYQQLK PIGSGAQGIV CAAFDTVLGI NVAVKKLSRP 
FQNQTHAKRA YRELVLLKCV NHKNIISLLN VFTPQKTLEE FQDVYLVMEL MDANLCQVIH 
MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTACTNF 
MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMAEMVL HKVLFPGRDY IDQWNKVIEQ 
LGTPSAEFMK KLQPTVRNYV ENRPKYPGIK FEELFPDWIF PSESERDKIK TSQARDLLSK 
MLVIDPDKRI SVDEALRHPY ITVWYDPAEA EAPPPQIYDA QLEEREHAIE EWKELIYKEV 
MDWEERSKNG VKDQPSDAAV SSKATPSQSS SINDISSMST EHTLASDTDS SLDASTGPLE 
GCR

Genular Protein ID: 55853037

Symbol: Q8C094_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8C094

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 323
Mass: 37924
Checksum: 752C07CCCEDC8074
Sequence:

RPFQNQTHAK RAYRELVLLK CVNHKNIISL LNVFTPQKTL EEFQDVYLVM ELMDANLCQV 
IHMELDHERM SYLLYQMLCG IKHLHSAGII HRDLKPSNIV VKSDCTLKIL DFGLARTACT 
NFMKTPYVVT RYYRAPEVIL GMGYKENVDI WSVGCIMAEM VLHKVLFPGR DYIDQWNKVI 
EQLGTPSAEF MKKLQPTVRN YVENRPKYPG IKFEELFPDW IFPSESERDK IKTSQARDLL 
SKMLVIDPDK RISVDEALRH PYITVWYDPA EAEAPPPQIY DAQLEEREHA IEEWKELIYK 
EVMDWEERSK NGVKDQPSAQ MQQ

Genular Protein ID: 3435164372

Symbol: Q5NCK8_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q5NCK8

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 423
Mass: 48017
Checksum: EE549B9F4F12F421
Sequence:

MSDSKSDGQF YSVQVADSTF TVLKRYQQLK PIGSGAQGIV CAAFDTVLGI NVAVKKLSRP 
FQNQTHAKRA YRELVLLKCV NHKNIISLLN VFTPQKTLEE FQDVYLVMEL MDANLCQVIH 
MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTACTNF 
MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGELVK GCVIFQGTDH IDQWNKVIEQ 
LGTPSAEFMK KLQPTVRNYV ENRPKYPGIK FEELFPDWIF PSESERDKIK TSQARDLLSK 
MLVIDPDKRI SVDEALRHPY ITVWYDPAEA EAPPPQIYDA QLEEREHAIE EWKELIYKEV 
MDWEERSKNG VKDQPSDAAV SSKATPSQSS SINDISSMST EHTLASDTDS SLDASTGPLE 
GCR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mapk9

Associated with

Other Information

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2. PubMed ID: 9806643

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a scaffold factor in the JNK signaling pathway. PubMed ID: 10523642

Analysis of splicing of four mouse JNK/SAPKalpha variants. PubMed ID: 10674476

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

JNK is required for effector T-cell function but not for T-cell activation. PubMed ID: 10811224

Requirement of the JIP1 scaffold protein for stress-induced JNK activation. PubMed ID: 11562351

Common and divergent roles for members of the mouse DCX superfamily. PubMed ID: 16628014

JNK2 is a positive regulator of the cJun transcription factor. PubMed ID: 16973441

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Activity of all JNK isoforms contributes to neurite growth in spiral ganglion neurons. PubMed ID: 21554942

JNK regulates the photic response of the mammalian circadian clock. PubMed ID: 22441692

POSH regulates CD4+ T cell differentiation and survival. PubMed ID: 27084103

Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells. PubMed ID: 29153991

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Database document:

PubMed ID: 9806643

PubMed ID: 10523642

PubMed ID: 10674476

PubMed ID: 16141072

PubMed ID: 19468303

PubMed ID: 15489334

PubMed ID: 10811224

PubMed ID: 11562351

PubMed ID: 16628014

PubMed ID: 16973441

PubMed ID: 18034455

PubMed ID: 21183079

PubMed ID: 21554942

PubMed ID: 22441692

PubMed ID: 27084103

PubMed ID: 29153991

PubMed ID: 10349636

PubMed ID: 11042159

PubMed ID: 11076861

PubMed ID: 11217851

PubMed ID: 12466851

PubMed ID: 16141073

PubMed ID: 10349636

PubMed ID: 11042159

PubMed ID: 11076861

PubMed ID: 11217851

PubMed ID: 12466851

PubMed ID: 16141073