Plod3 | ENSMUSG00000004846 | NCBI 26433

Details for: Plod3

Gene ID: 26433

Symbol: Plod3

Ensembl ID: ENSMUSG00000004846

Description: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3

Associated with

Collagen biosynthesis and modifying enzymes
(R-MMU-1650814)
Collagen formation
(R-MMU-1474290)
Extracellular matrix organization
(R-MMU-1474244)
Basement membrane assembly
(GO:0070831)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen fibril organization
(GO:0030199)
Collagen metabolic process
(GO:0032963)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum lumen
(GO:0005788)
Endoplasmic reticulum membrane
(GO:0005789)
Endothelial cell morphogenesis
(GO:0001886)
Epidermis morphogenesis
(GO:0048730)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Hydroxylysine biosynthetic process
(GO:0046947)
In utero embryonic development
(GO:0001701)
Iron ion binding
(GO:0005506)
L-ascorbic acid binding
(GO:0031418)
Lung morphogenesis
(GO:0060425)
Metal ion binding
(GO:0046872)
Neural tube development
(GO:0021915)
Peptidyl-lysine hydroxylation
(GO:0017185)
Procollagen-lysine 5-dioxygenase activity
(GO:0008475)
Procollagen galactosyltransferase activity
(GO:0050211)
Procollagen glucosyltransferase activity
(GO:0033823)
Protein localization
(GO:0008104)
Protein o-linked glycosylation
(GO:0006493)
Rough endoplasmic reticulum
(GO:0005791)
Small molecule binding
(GO:0036094)
Trans-golgi network
(GO:0005802)
Vasodilation
(GO:0042311)

Other Information

Proteins

Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3

Genular Protein ID: 2425622734

Symbol: PLOD3_MOUSE

Name: Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3

UniProtKB Accession Codes:

Q9R0E1 Q542E0 Q9CYY9

Database IDs:

Citations:

PubMed ID: 10429951

Title: Characterization of cDNAs for mouse lysyl hydroxylase 1, 2 and 3, their phylogenetic analysis and tissue-specific expression in the mouse.

PubMed ID: 10429951

DOI: 10.1016/s0945-053x(99)00016-5

PubMed ID: 11334715

Title: Complete genomic structure of mouse lysyl hydroxylase 2 and lysyl hydroxylase 3/collagen glucosyltransferase.

PubMed ID: 11334715

DOI: 10.1016/s0945-053x(01)00130-5

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15377789

Title: Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice.

PubMed ID: 15377789

DOI: 10.1073/pnas.0404966101

PubMed ID: 16447251

Title: Lysyl hydroxylase 3 (LH3) modifies proteins in the extracellular space, a novel mechanism for matrix remodeling.

PubMed ID: 16447251

DOI: 10.1002/jcp.20596

PubMed ID: 16467571

Title: Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes.

PubMed ID: 16467571

DOI: 10.1242/jcs.02780

PubMed ID: 17873278

Title: Secretion and assembly of type IV and VI collagens depend on glycosylation of hydroxylysines.

PubMed ID: 17873278

DOI: 10.1074/jbc.m704198200

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21220425

Title: Lysyl hydroxylase 3 glucosylates galactosylhydroxylysine residues in type I collagen in osteoblast culture.

PubMed ID: 21220425

DOI: 10.1074/jbc.m110.178509

PubMed ID: 21465473

Title: Lysyl hydroxylase 3 is secreted from cells by two pathways.

PubMed ID: 21465473

DOI: 10.1002/jcp.22774

PubMed ID: 23209641

Title: The activities of lysyl hydroxylase 3 (LH3) regulate the amount and oligomerization status of adiponectin.

PubMed ID: 23209641

DOI: 10.1371/journal.pone.0050045

PubMed ID: 25419660

Title: Lysyl hydroxylase 3 modifies lysine residues to facilitate oligomerization of mannan-binding lectin.

PubMed ID: 25419660

DOI: 10.1371/journal.pone.0113498

Sequence Information:

Length: 741
Mass: 84922
Checksum: D1B79B386339D9F4
Sequence:

MAAAGPEPRL LLLLLLLLPP LPPVTSASDR PRGANAVNPD KLLVITVATA ETEGYRRFLQ 
SAEFFNYTVR TLGLGQEWRG GDVARTVGGG QKVRWLKKEM EKYADQKDMI IMFVDSYDVI 
LASSPTELLK KFVQSGSHLL FSAESFCWPE WGLAEQYPEV GMGKRFLNSG GFIGFAPTIH 
QIVRQWNYKD DDDDQLFYTQ LYLDPGLREK LKLSLDHKSR IFQNLNGALD EVILKFDQNR 
VRIRNVAYDT LPVVVHGNGP TKLQLNYLGN YVPNGWTPQG GCGFCNQTLR TLPGGQPPPR 
VLLAVFVEQP TPFLPRFLQR LLLLDYPPDR ISLFLHNSEV YHEPHIADAW PQLQDHFSAV 
KLVGPEEALS AGEARDMAMD SCRQNPECEF YFSLDADAVL TNPETLRVLI EQNRKVIAPM 
LSRHGKLWSN FWGALSPNEY YARSEDYVEL VQRKRVGVWN VPYISQAYVI RGETLRTELP 
QKEVFSSSDT DPDMAFCKSV RDKGIFLHLS NQHEFGRLLA TSRYDTDHLH PDLWQIFDNP 
VDWREQYIHE NYSRALDGEG LVEQPCPDVY WFPLLTEQMC DELVEEMEHY GQWSGGRHED 
SRLAGGYENV PTVDIHMKQV GYEDQWLQLL RTYVGPMTEY LFPGYHTKTR AVMNFVVRYR 
PDEQPSLRPH HDSSTFTLNV ALNHKGVDYE GGGCRFLRYD CRISSPRKGW ALLHPGRLTH 
YHEGLPTTRG TRYIMVSFVD P

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Plod3

Associated with

Other Information

Characterization of cDNAs for mouse lysyl hydroxylase 1, 2 and 3, their phylogenetic analysis and tissue-specific expression in the mouse. PubMed ID: 10429951

Complete genomic structure of mouse lysyl hydroxylase 2 and lysyl hydroxylase 3/collagen glucosyltransferase. PubMed ID: 11334715

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice. PubMed ID: 15377789

Lysyl hydroxylase 3 (LH3) modifies proteins in the extracellular space, a novel mechanism for matrix remodeling. PubMed ID: 16447251

Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes. PubMed ID: 16467571

Secretion and assembly of type IV and VI collagens depend on glycosylation of hydroxylysines. PubMed ID: 17873278

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Lysyl hydroxylase 3 glucosylates galactosylhydroxylysine residues in type I collagen in osteoblast culture. PubMed ID: 21220425

Lysyl hydroxylase 3 is secreted from cells by two pathways. PubMed ID: 21465473

The activities of lysyl hydroxylase 3 (LH3) regulate the amount and oligomerization status of adiponectin. PubMed ID: 23209641

Lysyl hydroxylase 3 modifies lysine residues to facilitate oligomerization of mannan-binding lectin. PubMed ID: 25419660