Details for: Prnd

Gene ID: 26434

Symbol: Prnd

Ensembl ID: ENSMUSG00000027338

Description: prion like protein doppel

Associated with

Other Information

Genular Protein ID: 3215579253

Symbol: PRND_MOUSE

Name: Prion-like protein doppel

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10525406

Title: Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.

PubMed ID: 10525406

DOI: 10.1006/jmbi.1999.3108

PubMed ID: 10930132

Title: Identification of a novel gene encoding a PrP-like protein expressed as chimeric transcripts fused to PrP exon1/2 in ataxic mouse line with a disrupted PrP gene.

PubMed ID: 10930132

DOI: 10.1023/a:1007059827541

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10842180

Title: Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein: expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss.

PubMed ID: 10842180

DOI: 10.1074/jbc.m003888200

PubMed ID: 12110578

Title: Absence of the prion protein homologue Doppel causes male sterility.

PubMed ID: 12110578

DOI: 10.1093/emboj/cdf386

PubMed ID: 15161660

Title: Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knockout mice.

PubMed ID: 15161660

DOI: 10.1016/s0002-9440(10)63784-4

PubMed ID: 15007175

Title: Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions.

PubMed ID: 15007175

DOI: 10.1073/pnas.0400131101

PubMed ID: 11226243

Title: Two different neurodegenerative diseases caused by proteins with similar structures.

PubMed ID: 11226243

DOI: 10.1073/pnas.051627998

PubMed ID: 16388591

Title: NMR solution structure of the peptide fragment 1-30, derived from unprocessed mouse Doppel protein, in DHPC micelles.

PubMed ID: 16388591

DOI: 10.1021/bi051313f

Sequence Information:

  • Length: 179
  • Mass: 20442
  • Checksum: FC8B788259EE40F2
  • Sequence:
  • MKNRLGTWWV AILCMLLASH LSTVKARGIK HRFKWNRKVL PSSGGQITEA RVAENRPGAF 
    IKQGRKLDID FGAEGNRYYA ANYWQFPDGI YYEGCSEANV TKEMLVTSCV NATQAANQAE 
    FSREKQDSKL HQRVLWRLIK EICSAKHCDF WLERGAALRV AVDQPAMVCL LGFVWFIVK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.