Slc27a1 | ENSMUSG00000031808 | NCBI 26457

Details for: Slc27a1

Gene ID: 26457

Symbol: Slc27a1

Ensembl ID: ENSMUSG00000031808

Description: solute carrier family 27 (fatty acid transporter), member 1

Associated with

Slc-mediated transmembrane transport
(R-MMU-425407)
Transport of fatty acids
(R-MMU-804914)
Transport of small molecules
(R-MMU-382551)
Transport of vitamins, nucleosides, and related molecules
(R-MMU-425397)
Adiponectin-activated signaling pathway
(GO:0033211)
Arachidonate-coa ligase activity
(GO:0047676)
Basal plasma membrane
(GO:0009925)
Biotin import across plasma membrane
(GO:1905135)
Biotin transmembrane transporter activity
(GO:0015225)
Biotin transport
(GO:0015878)
Cardiolipin biosynthetic process
(GO:0032049)
Caveola
(GO:0005901)
Cytoplasmic vesicle
(GO:0031410)
Efflux transmembrane transporter activity
(GO:0015562)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Export across plasma membrane
(GO:0140115)
Fatty acid transmembrane transporter activity
(GO:0015245)
Fatty acid transport
(GO:0015908)
Glucose import in response to insulin stimulus
(GO:0044381)
Identical protein binding
(GO:0042802)
Lipid transport across blood-brain barrier
(GO:1990379)
Long-chain fatty acid-coa ligase activity
(GO:0004467)
Long-chain fatty acid import across plasma membrane
(GO:0015911)
Long-chain fatty acid import into cell
(GO:0044539)
Long-chain fatty acid metabolic process
(GO:0001676)
Long-chain fatty acid transmembrane transporter activity
(GO:0005324)
Long-chain fatty acid transport
(GO:0015909)
Medium-chain fatty acid transport
(GO:0001579)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial outer membrane
(GO:0005741)
Negative regulation of phospholipid biosynthetic process
(GO:0071072)
Nucleotide binding
(GO:0000166)
Oleate transmembrane transporter activity
(GO:1901480)
Oleoyl-coa ligase activity
(GO:0090434)
Phosphatidic acid biosynthetic process
(GO:0006654)
Phosphatidylcholine biosynthetic process
(GO:0006656)
Phosphatidylethanolamine biosynthetic process
(GO:0006646)
Phosphatidylglycerol biosynthetic process
(GO:0006655)
Phosphatidylinositol biosynthetic process
(GO:0006661)
Phosphatidylserine biosynthetic process
(GO:0006659)
Plasma membrane
(GO:0005886)
Positive regulation of heat generation
(GO:0031652)
Positive regulation of triglyceride biosynthetic process
(GO:0010867)
Protein binding
(GO:0005515)
Protein serine/threonine kinase activator activity
(GO:0043539)
Response to cold
(GO:0009409)
Response to insulin
(GO:0032868)
Very long-chain fatty acid-coa ligase activity
(GO:0031957)

Other Information

Proteins

Arachidonate--CoA ligase

Genular Protein ID: 3230146685

Symbol: S27A1_MOUSE

Name: Arachidonate--CoA ligase

UniProtKB Accession Codes:

Q60714

Database IDs:

Citations:

PubMed ID: 7954810

Title: Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein.

PubMed ID: 7954810

DOI: 10.1016/0092-8674(94)90252-6

PubMed ID: 9765271

Title: Characterization of the murine fatty acid transport protein gene and its insulin response sequence.

PubMed ID: 9765271

DOI: 10.1074/jbc.273.42.27420

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9786857

Title: Substitution of alanine for serine 250 in the murine fatty acid transport protein inhibits long chain fatty acid transport.

PubMed ID: 9786857

DOI: 10.1074/jbc.273.44.28642

PubMed ID: 9671728

Title: A family of fatty acid transporters conserved from mycobacterium to man.

PubMed ID: 9671728

DOI: 10.1073/pnas.95.15.8625

PubMed ID: 10593920

Title: The fatty acid transport protein (FATP1) is a very long chain acyl-CoA synthetase.

PubMed ID: 10593920

DOI: 10.1074/jbc.274.51.36300

PubMed ID: 10471110

Title: Molecular aspects of fatty acid transport: mutations in the IYTSGTTGXPK motif impair fatty acid transport protein function.

PubMed ID: 10471110

DOI: 10.1016/s0952-3278(99)80001-5

PubMed ID: 11470793

Title: Membrane topology of the murine fatty acid transport protein 1.

PubMed ID: 11470793

DOI: 10.1074/jbc.m105556200

PubMed ID: 12235169

Title: FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells.

PubMed ID: 12235169

DOI: 10.1194/jlr.m200130-jlr200

PubMed ID: 12533547

Title: Oligomerization of the murine fatty acid transport protein 1.

PubMed ID: 12533547

DOI: 10.1074/jbc.m212469200

PubMed ID: 11970897

Title: Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes.

PubMed ID: 11970897

DOI: 10.1016/s1534-5807(02)00143-0

PubMed ID: 12556534

Title: Characterization of a heart-specific fatty acid transport protein.

PubMed ID: 12556534

DOI: 10.1074/jbc.m211412200

PubMed ID: 12937175

Title: Characterization of the acyl-CoA synthetase activity of purified murine fatty acid transport protein 1.

PubMed ID: 12937175

DOI: 10.1074/jbc.m306575200

PubMed ID: 14991074

Title: Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle.

PubMed ID: 14991074

DOI: 10.1172/jci18917

PubMed ID: 15897321

Title: Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells.

PubMed ID: 15897321

DOI: 10.1152/ajpcell.00271.2004

PubMed ID: 15699031

Title: Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast.

PubMed ID: 15699031

DOI: 10.1074/jbc.m409598200

PubMed ID: 19527715

Title: Additive effects of insulin and muscle contraction on fatty acid transport and fatty acid transporters, FAT/CD36, FABPpm, FATP1, 4 and 6.

PubMed ID: 19527715

DOI: 10.1016/j.febslet.2009.06.020

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24858472

Title: Fatty acid transport protein 1 (FATP1) localizes in mitochondria in mouse skeletal muscle and regulates lipid and ketone body disposal.

PubMed ID: 24858472

DOI: 10.1371/journal.pone.0098109

PubMed ID: 28178239

Title: EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice.

PubMed ID: 28178239

DOI: 10.1038/nature21380

Sequence Information:

Length: 646
Mass: 71276
Checksum: 910B92BA8D985B4C
Sequence:

MRAPGAGTAS VASLALLWFL GLPWTWSAAA AFCVYVGGGG WRFLRIVCKT ARRDLFGLSV 
LIRVRLELRR HRRAGDTIPC IFQAVARRQP ERLALVDASS GICWTFAQLD TYSNAVANLF 
RQLGFAPGDV VAVFLEGRPE FVGLWLGLAK AGVVAALLNV NLRREPLAFC LGTSAAKALI 
YGGEMAAAVA EVSEQLGKSL LKFCSGDLGP ESILPDTQLL DPMLAEAPTT PLAQAPGKGM 
DDRLFYIYTS GTTGLPKAAI VVHSRYYRIA AFGHHSYSMR AADVLYDCLP LYHSAGNIMG 
VGQCVIYGLT VVLRKKFSAS RFWDDCVKYN CTVVQYIGEI CRYLLRQPVR DVEQRHRVRL 
AVGNGLRPAI WEEFTQRFGV PQIGEFYGAT ECNCSIANMD GKVGSCGFNS RILTHVYPIR 
LVKVNEDTME PLRDSEGLCI PCQPGEPGLL VGQINQQDPL RRFDGYVSDS ATNKKIAHSV 
FRKGDSAYLS GDVLVMDELG YMYFRDRSGD TFRWRGENVS TTEVEAVLSR LLGQTDVAVY 
GVAVPGVEGK AGMAAIADPH SQLDPNSMYQ ELQKVLASYA RPIFLRLLPQ VDTTGTFKIQ 
KTRLQREGFD PRQTSDRLFF LDLKQGRYVP LDERVHARIC AGDFSL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc27a1

Associated with

Other Information

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. PubMed ID: 7954810

Characterization of the murine fatty acid transport protein gene and its insulin response sequence. PubMed ID: 9765271

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Substitution of alanine for serine 250 in the murine fatty acid transport protein inhibits long chain fatty acid transport. PubMed ID: 9786857

A family of fatty acid transporters conserved from mycobacterium to man. PubMed ID: 9671728

The fatty acid transport protein (FATP1) is a very long chain acyl-CoA synthetase. PubMed ID: 10593920

Molecular aspects of fatty acid transport: mutations in the IYTSGTTGXPK motif impair fatty acid transport protein function. PubMed ID: 10471110

Membrane topology of the murine fatty acid transport protein 1. PubMed ID: 11470793

FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells. PubMed ID: 12235169

Oligomerization of the murine fatty acid transport protein 1. PubMed ID: 12533547

Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes. PubMed ID: 11970897

Characterization of a heart-specific fatty acid transport protein. PubMed ID: 12556534

Characterization of the acyl-CoA synthetase activity of purified murine fatty acid transport protein 1. PubMed ID: 12937175

Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle. PubMed ID: 14991074

Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells. PubMed ID: 15897321

Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast. PubMed ID: 15699031

Additive effects of insulin and muscle contraction on fatty acid transport and fatty acid transporters, FAT/CD36, FABPpm, FATP1, 4 and 6. PubMed ID: 19527715

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Fatty acid transport protein 1 (FATP1) localizes in mitochondria in mouse skeletal muscle and regulates lipid and ketone body disposal. PubMed ID: 24858472

EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice. PubMed ID: 28178239